Nicosulfuron

In the event of fire, wear self-contained breathing apparatus. Use personal protective equipment. Evacuate personnel and keep upwind of fire. If area is heavily exposed to fire and if conditions permit, let fire burn itself out since water may increase the area contaminated. Burning chemicals may produce by-products more toxic than the original material. Use water spray. Runoff from fire control may be a pollution hazard. Do not allow run-off from fire fighting to enter drains or water courses. Cool containers / tanks with water spray. Control Runoff. /DuPont Accent Q Herbicide/

Extinguishing Media: Water spray, Foam, Dry chemical, Carbon dioxide (CO2). /DuPont Accent Q Herbicide/

Do not contaminate water, other pesticides, fertilizer, food or feed in storage. Store in original container. Store in a cool, dry place. /DuPont Accent Q Herbicide/

Store product in original container only. Do not contaminate water, other pesticides, fertilizer, food or feed in storage. Store in a cool, dry place. /DuPont Accent Q Herbicide/

Do not contaminate water when disposing of equipment rinsewater. /DuPont Accent Q Herbicide/

Safeguards (Personnel): Evacuate personnel, thoroughly ventilate area, use self-contained breathing apparatus. /DuPont Accent Q Herbicide/

Accidental Release Measures: Prevent material from entering sewers, waterways, or low areas. Follow applicable Federal, State/Provincial and Local laws/regulations. /DuPont Accent Q Herbicide/

Spill Cleanup: Sweep up and shovel into suitable containers for disposal. /DuPont Accent Q Herbicide/

SRP: The most favorable course of action is to use an alternative chemical product with less inherent propensity for occupational harm/injury/toxicity or environmental contamination. Recycle any unused portion of the material for its approved use or return it to the manufacturer or supplier. Ultimate disposal of the chemical must consider: the material's impact on air quality; potential migration in soil or water; effects on animal and plant life; and conformance with environmental and public health regulations.

Do not contaminate water, food, or feed by disposal. Waste resulting from the use of this product may be disposed of on site or at an approved waste disposal facility. /DuPont Accent Q Herbicide/

SRP: Wastewater from contaminant suppression, cleaning of protective clothing/equipment, or contaminated sites should be contained and evaluated for subject chemical or decomposition product concentrations. Concentrations shall be lower than applicable environmental discharge or disposal criteria. Alternatively, pretreatment and/or discharge to a permitted wastewater treatment facility is acceptable only after review by the governing authority and assurance that "pass through" violations will not occur. Due consideration shall be given to remediation worker exposure (inhalation, dermal and ingestion) as well as fate during treatment, transfer and disposal. If it is not practicable to manage the chemical in this fashion, it must be evaluated in accordance with EPA 40 CFR Part 261, specifically Subpart B, in order to determine the appropriate local, state and federal requirements for disposal.

Use this product only in accordance with its labeling and with the Worker Protection Standard, 40 CFR part 170. /DuPont Accent Q Herbicide/

Do not apply directly to water, to areas where surface water is present or to intertidal areas below the mean high water mark. ... Do not apply where/when conditions could favor runoff. /DuPont Accent Q Herbicide/

Users should: Wash hands before eating, drinking, chewing gum, using tobacco or using the toilet. Remove clothing immediately if pesticide gets inside. Then wash thoroughly and put on clean clothing. /DuPont Accent Q Herbicide/

Follow manufacturer's instructions for cleaning/maintaining personal protective equipment (PPE). If no such instructions for washables, use detergent and hot water. Keep and wash PPE separately from other laundry. /DuPont Accent Q Herbicide/

For more Preventive Measures (Complete) data for Nicosulfuron (9 total), please visit the HSDB record page.

Tolerances are established for residues of the herbicide nicosulfuron, including its metabolites and degradates, in or on the commodities in the following table [below]. Compliance with the tolerance levels specified in the following table [below] is to be determined by measuring only nicosulfuron, 3-Pyridinecarboxamide, 2-[[[[(4,6-dimethoxy-2-pyrimidinyl)amino] carbonyl]amino]sulfonyl]-N,N-dimethyl-. [Table#7851]

Time-limited tolerances specified in the following table [below] are established for residues of the herbicide nicosulfuron, 3-Pyridinecarboxamide, 2-[[[[(4,6-dimethoxy-2-pyrimidinyl)amino] carbonyl]amino]sulfonyl]-N,N-dimethyl-, in or on the specified agricultural commodities, resulting from use of the pesticide pursuant to FFIFRA section 18 emergency exemptions. The tolerances expire and are revoked on the date specified in the table. [Table#7852]

Applicators and other handlers must wear: Long-sleeved shirt and long pants. Chemical resistant gloves Category A (such as butyl rubber, natural rubber, neoprene rubber, or nitrile rubber), all > 14 mils. Shoes plus socks. /DuPont Accent Q Herbicide/

Chemical-resistant gloves ... protective eyewear.

... Restricted-entry interval (REI) of 4 hours. Personal protective equipment (PPE) required for early entry to treated areas that is permitted under the Worker Protection Standard and that involves contact with anything that has been treated, such as plants, soil, or water is: Coveralls, chemical resistant gloves Category A (such as butyl rubber, natural rubber, neoprene rubber, or nitrile rubber), all > or = 14 mils. Shoes plus socks. /DuPont Accent Q Herbicide/

LC50; Species: Anas platyrhynchos (Mallard Duck, age 8 days) diet >5000 ppm for 8 days

LC50; Species: Colinus virginianus (Northern Bobwhite Quail, juvenile) diet >5000 ppm for 8 days

LD50; Species: Colinus virginianus (Northern Bobwhite Quail, age 38 weeks) oral via capsule >2000 mg/kg

LD50; Species: Apis mellifera (Honey Bee, adult) topical >20 ug/bee for 48 hr

For more Ecotoxicity Values (Complete) data for Nicosulfuron (13 total), please visit the HSDB record page.

TERRESTRIAL FATE: Based on a classification scheme(1), a Koc range of 63.0 to 567.1(2) indicates that nicosulfuron is expected to have very high to moderate mobility in soil(SRC). Sulfonylurea herbicides, such as nicosulfuron, are more mobile in alkaline soils and in soils with lower organic matter content(3). The pKa of nicosulfuron is 4.60(4), indicating that this compound will partially exist in the anion form in the environment and anions generally do not adsorb more strongly to soils containing organic carbon and clay than their neutral counterparts(5). Volatilization of nicosulfuron from moist soil surfaces is not expected to be an important fate process(SRC) given an estimated Henry's Law constant of 4.1X10-18 atm-cu m/mole(6). Nicosulfuron is not expected to volatilize from dry soil surfaces(SRC) based upon a vapor pressure of <6X10-12 mm Hg at 25 °C(4). Nicosulfuron was less than 1.3% mineralized following 41 days of incubation using 5 soils(7) indicating that biodegradation is not an important environmental fate process in soil(SRC).

TERRESTRIAL FATE: Average field half-life is approximately 21 days at pH 6.5. Half-lives were as follows: 0.75 mo for a soil with 1.3% organic matter and pH 5.5 at Stonevill MS; 0.25 mo for a soil with 1.4% organic matter and pH 6.0 at Newark, DE; 0.5 mo for a soil with 2.4% organic matter and pH 6.0 at Bradenton, FL; 1 mo for a soil with 4.4% organic matter and pH 6.9 at Stettler, Alberta /Canada/

TERRESTRIAL FATE: A field study was undertaken in Tennessee in a surface soil to track the dissipation of nicosulfuron. Field plots were set up in 1997 and 1998 on Sequatchie silt loam (pH 5.7, cation exchange capacity 7.0 cmol/g, 1.3% organic matter, and sand/silt/clay was 27/59/14, respectively). Nicosulfuron was applied at 46 g/ha and in combination with rimsulfuron at 46 g/ha. First order rate constants and associated half-lives observed in 1997 were: 0.13/day, half-life 5.3 days (alone); 0.17/day, half-life 4.2 days (mixture). For 1998: 0.54/day, half-life 1.3 days (alone); 0.32/day, half-life 2.2 days (mixture). Under laboratory conditions, moist Sequatchie silt loam soil at 50% field capacity was employed. Nicosulfuron was added at a concentration of 50.0 ng/g soil, both alone and in combination with rimsulfuron and samples were incubated at 30 °C. First order rate constants and associated half-lives observed were: 0.34/day, half-life 2.0 days (alone); 0.30/day, half-life 2.3 days (mixture)(1).

AQUATIC FATE: Based on a classification scheme(1), Koc values ranging from 63.0 to 567.1 in soils of varying clay mineralogy(2), indicates that nicosulfuron is not expected to adsorb to suspended solids and sediment(SRC). Volatilization of nicosulfuron from moist soil surfaces is not expected to be an important fate process(SRC) given an estimated Henry's Law constant of 4.1X10-18 atm-cu m/mole(4). According to a classification scheme(5), an estimated BCF of three(SRC), from its log Kow of -1.8(3) and a regression-derived equation(6), suggests the potential for bioconcentration in aquatic organisms is low(SRC). The main degradation pathway for nicosulfuron is hydrolysis of the sulfonylurea bridge(7). Nicosulfuron was less than 1.3% mineralized following 41 days of incubation using 5 soils(8) indicating that biodegradation is not an important environmental fate process in water(SRC).

ATMOSPHERIC FATE: According to a model of gas/particle partitioning of semivolatile organic compounds in the atmosphere(1), nicosulfuron, which has a vapor pressure of <6X10-12 mm Hg at 25 °C(2), is expected to exist solely in the particulate phase in the ambient atmosphere. Particulate-phase nicosulfuron may be removed from the air by wet or dry deposition(SRC). Photolysis half-lives in soil were 60-67 days and in water, 200-250 days at pH 7(2) suggesting that nicosulfuron may be susceptible to direct photolysis by sunlight(SRC).

EXPERIMENTAL: Two female goats weighing 43 kg (#1) and 34 kg (#2) (1.4 and 1.8 mg/kg body weight respectively), were dosed daily for 3 consecutive days in feed rations treated with (pyrimidine2-(14)C)nicosulfuron, sp. act., 62.2 uCi/mg, radiochemical purity, >95%, isotopic purity, 97%, and (pyridine-2-(14)C)nicosulfuron, sp. act., 62.9 uCi/mg, radiochemical purity, >95%, isotopic purity, >99%, respectively. Dosing capsules were prepared with the (14)C-labeled materials, 13C-enriched isomers (C2 position of each respective ring), and nonradioactive nicosulfuron. The capsules were analyzed prior to dosing by LSC for total (14)C-activity and by HPLC for chemical analysis. These capsules were imbedded in a larger gelatin capsule containing 6 g of goat chow. Goat #1 was housed for a 9-day acclimation period, while goat #2 was kept for 11 days. Both goats showed good health and milk production before and during dosing. The dosage represents a daily feeding level of approximately 60 ppm based on the average feed and hay consumption of 1 kg/day. Samples of milk, bile, urine, and feces were collected daily and analyzed by combustion/liquid scintillation counting. A control goat was not used in the study. Milk, bile, urine, and feces were collected at least one day prior to dosing for use as control samples. ... The total (14)C activity measured in milk (pyrimidinyl labeled) by combustion/ LSC was a maximum of 0.03 ppm (0.03% TRR). ...

/AQUATIC SPECIES/ The behavioral effects of short periods (2, 4, 6, 8 hr) of static exposure to prochloraz (imidazole fungicide) and nicosulfuron (sulfonylurea herbicide) were recorded in goldfish (Carassius auratus). Observations were also made in an olfactometer to assess the effects of 8-hr exposures to these two pesticides and to carbofuran (carbamate insecticide) on the behavioral responses to the flow of a solution of four L-amino acids (glycine, alanine, valine, taurine), mixed in the same relative proportions as in the urine of conspecifics. Each pesticide was tested at three sublethal concentrations (25, 50, 100 ug/L), and the behaviors recorded were related to swimming pattern, social interactions, and comfort movements. Static exposures to prochloraz affected horizontal displacements, burst swimming, grouping, and buccal movements. Static exposures to nicosulfuron affected burst swimming and grouping. In pesticide-unexposed fish (control), the flow of the amino acid solution induced attraction, decreased sheltering, and increased horizontal displacements, burst swimming, buccal movements, and antagonistic interactions. Compared to the controls, some of the behavioral responses to the solution of amino acids were significantly different after 8 hr of subacute exposure to prochloraz and carbofuran. Both pesticides decreased attraction and increased sheltering. In addition, carbofuran decreased buccal movements and antagonistic interactions. Contrastingly, exposure to nicosulfuron showed no significant effect. This study further confirms the great vulnerability of fish behavior and chemocommunication processes to exposure to waterborne pesticides.

/AQUATIC SPECIES/ Juvenile goldfish (Carassius auratus) were exposed to three widely used pesticides; carbofuran, diuron, and nicosulfuron. Acetylcholinesterase (AChE) activity and molecular forms of AChE were first characterized in brain and skeletal muscle of unexposed fish. Skeletal muscle had higher AChE activity than brain (306 and 215 nmol/min/mg protein, respectively). In brain, four molecular forms of AChE were found: A12, G4, G2, and G1. In the muscle, three molecular forms were found A12, A8, and G2. AChE activity was then evaluated in both tissues of fish exposed to different concentration of pesticides (5, 50, and 500 ug/L) for 6, 12, 24, and 48 hr. In brain, AChE activity was significantly inhibited during all the periods of exposure in response to 50 ug/L (19-28%) and 500 ug/L (85-87%) carbofuran. Such effect was observed in the muscle only at 500 ug/L (86-92%). Carbofuran had no effect on the distribution of molecular forms. Significant inhibitions (9-12%) of brain AChE activity were also observed in response to diuron and nicosulfuron at 500 ug/L during all periods of exposure and for 50 ug/L nicosulfuron after 24 and 48 hr. This study pointed out short-term effects of exposure to sublethal concentrations of the three pesticides, ranging among different chemical families, on brain and muscle AChE in goldfish.

Sulfonylurea herbicides, such as nicosulfuron, are more mobile in alkaline soils and in soils with lower organic matter content(1). Nicosulfuron was not highly mobile in soils with 2:1 clay minerology, possibly due to chemisorption on the clay minerals. The Koc of nicosulfuron using 10 Iowa soils ranged from 63.0 (Fruitfield Entic Hapludoll, pH 7.8, 0.33% organic matter, 2.1% clay) to 567.1 (Webster Typic Haplaquoll, pH 8.2, 0.61% organic matter, 34.1% clay). Using four Brazilian soils not characterized by a 2:1 clay minerology, the range was 86.6 (Typic Acrustox, pH 4.6, 2.16% organic matter, 60.0% clay) to 112.3 (Typic Acrustox, pH 4.8, 0.94% organic matter, 64.3% clay)(2). Koc values of 14.7, 63.7. 62.0. 82.7. and 31.5 were reported using 5 soils - three Mollisols from the North Central US (a sand, a silt loam, and a silt clay loam) and two Oxisols (a sandy clay loam from Brazil and a clay from Hawaii), respectively. Sorption increased with aging of soils(3). According to a classification scheme(4), this Koc range suggests that nicosulfuron is expected to have very high to moderate mobility in soil. Kd values in four sandy loams at 25 °C were: 0.16 (pH 6.6, 1.1% organic matter) to 1.73 (pH 5.4, 4.3% organic matter), and 0.05-0.7, soil specifications not listed(5). The pKa of nicosulfuron is 4.60(5), indicating that this compound will partially exist in the anion form in the environment and anions generally do not adsorb more strongly to soils containing organic carbon and clay than their neutral counterparts(6).

Average Koc is 39 mL/g at pH 6.5 ... Koc 38.4 and Kd for a soil with 1.1% organic matter and pH 6.6; Koc 28.8 and Kd 0.26 for a soil with 2.1% organic matter and pH 6.5; Koc 78,8 and Kd 1.73 for a soil with 4.3% organic matter an dpH 5.4

/GENOTOXICITY/ ... /Nicosulfuron/ (IN V9360-27) (90.6% a.i.) induced no significant damage to chromosomal structure of cultured human lymphocytes in the presence and absence of metabolic activation at 40, 200, 400 or 470 micrograms/mL concentrations. Cells were examined for chromosomal abnormalities. Nicosulfuron was not clastogenic under the conditions of this test. The maximum concentration tested 470 micrograms was the limit of the test compound solubility in the test system satisfies the guideline requirement even in the absence of cytotoxicity.

AEROBIC: Nicosulfuron at a concentration of 40.4 ug/mL and 4.88 kBq/mL was less than 1.3% mineralized following 41 days of incubation using 5 soils - three Mollisols from the North Central US (a sand, a silt loam, and a silt clay loam) and two Oxisols (a sandy clay loam from Brazil and a clay from Hawaii)(1). The half-life in an unclassified soil (pH 6.1, 5.1% organic matter, 25 °C) was 26 days(2).

ANAEROBIC: Nicosulfuron, present at 10 ug/mL sediment, exhibited degradation rate constants of 1.84X10-2/day and 0.37X10-2/day using a sediment from a stagnant, slow-moving stream near Athens, GA (Beaver Dam) and from a eutrophic pond (Cherokee Park), respectively, incubated at 25 °C(1). The corresponding half-lives are 38 and 182 days, respectively(SRC). Half-lives in the respective sterile controls were 55 days (1.25X10-2/day) and 65 days (1.06X10-2/day)(1).

An estimated BCF of three was calculated in fish for nicosulfuron(SRC), using a log Kow of -1.8(1) and a regression-derived equation(2). According to a classification scheme(3), this BCF suggests the potential for bioconcentration in aquatic organisms is low(SRC).

The Henry's Law constant for nicosulfuron is estimated as 4.1X10-18 atm-cu m/mole(1). This Henry's Law constant indicates that nicosulfuron is expected to be essentially nonvolatile from water and moist soil surfaces(2). Nicosulfuron is not expected to volatilize from dry soil surfaces(SRC) based upon a vapor pressure of 6.0X10-12 mm Hg(3).

/LABORATORY ANIMALS: Subchronic or Prechronic Exposure/ ... /Nicosulfuron/ (IN V9360-7) (90.4% a.i.) was administered to beagle dogs (4/sex/dose) by feeding at dose levels of 0, 250, 5000, or 20000 ppm (mean measured concentrations of 0, 9.23, 172.0, 710.0 mg/kg/day for males and 0, 9.14, 171.0, 683.0 mg/kg/day for females) for 90 days. Blood and urine samples were taken at 45 and 90 days for analysis. A slight decrease in neutrophils was seen at 90 days in the top dose females. No other effects (clinical, body weight changes, ophthalmology, gross and microscopic pathology) were noted with the compound. ...

/LABORATORY ANIMALS: Subchronic or Prechronic Exposure/ ... Nicosulfuron (IN V9360-7) (90.4% a.i.) was administered to CRL:CD-1(ICR)BR mice (15/sex/dose) by feeding at dose levels of 0, 300, 1500, 7500 or 10000 ppm (mean measured concentrations of 0, 43.9, 234.0, 1164.0, 1509.0 mg/kg/day for males and 0, 62.0, 323.0, 1537.0, 2016.0 mg/kg/day for females) for 90 days. No treatment-related signs of toxicity or mortality were attributed to the test material. Body weight and body weight gains were not affected by the treatment. Food consumption and food efficiency were unaffected by the compound intake. No ophthalmological changes related to the compound intake were reported. The primary effects of the compound administration on mice were on the hematologic parameters in both sexes. White blood cells and specifically neutrophils, lymphocytes, monocytes, and eosinophils were decreased with treatment. The most significant effects occurred in neutrophils in females at 90 days where decreases were seen at 1500 ppm and all doses above. Absolute spleen weights were decreased in females at the top dose of 10000 ppm, relative spleen weights were decreased as well, but not statistically significantly. No histopathological effects attributed to treatment were reported. ... The LOAEL derived from this study is 1500 ppm (234.0 / 323.0 mg/kg/day for males/ females) based on decreased hematological parameters, particularly the neutrophils, and the NOAEL is 300 ppm (43.9/ 62.0 mg/kg/day for males/ females). ...

/LABORATORY ANIMALS: Subchronic or Prechronic Exposure/ ... /Nicosulfuron/ (IN V9360-7) (90.4% a.i.) was administered to CRL:CD BR rats (10/sex/dose) by feeding at dose levels of 0, 300, 1500, 7500 or 20,000 ppm (mean measured concentrations of 0, 22.2, 107.0, 555.0, 1495.0 mg/kg/day for males and 0, 26.0, 133.0, 685.0, 1830.0 mg/kg/day for females) for 90 days. No treatment-related signs of toxicity or mortality were attributed to the test material. Body weight and body weight gains were not affected by the treatment. Food consumption and food efficiency were unaffected by the compound intake. No ophthalmological changes related to the compound intake were reported. The primary effects of the compound intake toxicity were reduction of platelets. There was a statistically significant decrease (p<0.05) but not in a dose dependent fashion in platelets in females at all doses tested both at the 45 and 90 day sacrifices. No other hematological parameters were significantly affected. Blood calcium and bilirubin were significantly depressed (p<0.05) at dose levels of 1500 ppm and above in males and females, but not in a dose-dependent fashion. Ketones were present in the urine of all treated males in a dose-related manner, but not in females. The hematological and urinary findings were not seen in the 24 month study in rats, ... No compound effects on organ weights, gross and microscopic pathology were seen. A LOAEL for subchronic toxicity of this test material is >20,000 ppm (1495/1830 mg/kg/day for males/females) and a NOAEL is 20,000 ppm (1495/1830 mg/kg/day for males/females). This is different from the conclusion of the original review of this study where no NOAEL was derived because of the assumed effects on blood platelets and urinary ketones.

The main degradation pathway for nicosulfuron is hydrolysis of the sulfonylurea bridge(1). Nicosulfuron at a concentration of 10 ug/mL exhibited hydrolysis rate constants of 12.40X10-2/day (pH 4, 22 °C), 128.16X10-2/day (pH 4, 40 °C), 2.13X10-2/day (pH 7, 40 °C), and 1.34X10-2/day (pH 10, 40 °C)(2); the corresponding half-lives were 5.6, 0.54, 33, and 53 days, respectively(SRC). A hydrolysis half-life of 15 days at pH 5 has been reported; however, nicosulfuron has also been reported as stable to hydrolysis at pH 7 and pH 9(3). Photolysis half-lives in soil were 60-67 days and in water, 14-19 days at pH 5, 200-250 days at pH 7, and 180-200 days at pH 9. Other values reported in soil were 24-43 days at 20 °C, 80-143 days at 20 °C, and in water 15 days at pH 5 and 20 °C(3). Therefore nicosulfuron may be susceptible to direct photolysis by sunlight(SRC).

Tolerances are established for residues of the herbicide nicosulfuron, including its metabolites and degradates, in or on the commodities in the following table [below]. Compliance with the tolerance levels specified in the following table [below] is to be determined by measuring only nicosulfuron, 3-Pyridinecarboxamide, 2-[[[[(4,6-dimethoxy-2-pyrimidinyl)amino] carbonyl]amino]sulfonyl]-N,N-dimethyl-. [Table#7853]

Reregistration Eligibility Decision (RED) Scheduled for 2012

Time-limited tolerances specified in the following table [below] are established for residues of the herbicide nicosulfuron, 3-Pyridinecarboxamide, 2-[[[[(4,6-dimethoxy-2-pyrimidinyl)amino] carbonyl]amino]sulfonyl]-N,N-dimethyl-, in or on the specified agricultural commodities, resulting from use of the pesticide pursuant to FFIFRA section 18 emergency exemptions. The tolerances expire and are revoked on the date specified in the table. [Table#7854]

The Agency has evaluated all current registered uses of nicosulfuron and has determined that there is a reasonable certainty that no harm to any population subgroup will result from exposure to nicosulfuron when considering dietary exposure and all other non-occupational sources of pesticide exposure for which there is reliable information. Therefore, no mitigation measures are needed and current tolerances at 40 CFR 180.454 for nicosulfuron are now considered reassessed under section 408(q) of the FFDCA.

New Active Ingredients ... includes chemicals not previously registered as pesticides, as well as pesticide active ingredients initially registered after November 1, 1984 and that currently have active product registrations. By law, these pesticides must meet new safety standards, such as those described in the Food Quality Protection Act of 1996 and, if new safety standards are met, will be reviewed again on a 15-year cycle. Nicosulfuron (Accent) is designated by EPA as a New Pesticide Active Ingredient. Active Ingredient Number: 129008; Type of Pesticide: conventional - herbicide; Use Site: food use/corn; Year: 1990.

For nicosulfuron (USEPA/OPP Pesticide Code: 129008) ACTIVE products with label matches. /SRP: Registered for use in the U.S. but approved pesticide uses may change periodically and so federal, state and local authorities must be consulted for currently approved uses./

Sulfonyl herbicide registered for early-postemergent and postemergent use on corn

Herbicide

Water dispersible granule, suspension concentrate.

Premix Partners: Atrazine; Clopyralid; Dicamba; Diflufenzopyr; Flumetsulam; Metsulfuron-methyl; Rimsulfuron.

Oil dispersion; suspension concentrate; water dispersible granule.

Eti 114 01 H (Nufam Americas Inc.) Nicosulfuron 75%

For more Formulations/Preparations (Complete) data for Nicosulfuron (42 total), please visit the HSDB record page.

Environmental transformation -> Pesticides (parent, predecessor)

Herbicides

The WHO Recommended Classification of Pesticides by Hazard identifies nicosulfuron as unlikely to present an acute hazard in normal use; Main Use: herbicide.

Following first commercial use in 1990, its use has grown to 12% of surveyed corn acres, with a total of 111 thousand kg applied in 1996