Basic information
- CAS
61424-76-8- Standard SMILES
Nc1oc2ccccc2c(=O)c1C=O- InChIKey
TVGIYZVZBKAJRR-UHFFFAOYSA-N- Molecular formula
- C10H7NO3
- Average molar mass
- 189.17 g/mol
- Monoisotopic mass
- 189.04259308
Overview
structure in first source
Names & identifiers
- Preferred name
- 2-Aminochromone-3-carboxaldehyde
- IUPAC
- 2-amino-4-oxochromene-3-carbaldehyde
- English name
- 2-Amino-3-formylchromone
- Molecular formula
- C10H7NO3
- Molecular weight
- 189.17
Names & synonyms
Show more names
Database identifiers
- CAS
61424-76-8- PubChem CID
- 735928
- DTXSID
DTXSID50352884- ChEMBL
CHEMBL87426- EC Number
- 624-966-3
- Nikkaji
- J1.869.084E
Properties
Computed structural properties
- XLogP
- 1.3
- Topological polar surface area
- 69.4 Ų
- Hydrogen bond donors
- 1
- Hydrogen bond acceptors
- 4
- Rotatable bonds
- 1
- Heavy atoms
- 14
- Formal charge
- 0
- Complexity
- 308
Physicochemical properties
- Melting point
- 249 °C · 249 °C (dec.) (lit.)
- Boiling point
- 401.2 · 401.2±45.0 °C(Predicted)
- Density
- 1.486 · 1.486±0.06 g/cm3(Predicted)
- pka
- 1.31 · 1.31±0.20(Predicted)
- form
- powder to crystal
- color
- White to Orange to Green
- InChI
- 1S/C10H7NO3/c11-10-7(5-12)9(13)6-3-1-2-4-8(6)14-10/h1-5H,11H2
- InChIKey
- TVGIYZVZBKAJRR-UHFFFAOYSA-N
- SMILES
- [H]C(=O)C1=C(N)Oc2ccccc2C1=O
- CAS DataBase Reference
- 61424 · 61424-76-8(CAS DataBase Reference)
- UNSPSC Code
- 12352100 · 12352100
- NACRES
- 22 · NA.22
- Symbol(GHS)
- 7 · GHS07
- Signal word
- Warning
- Hazard statements
- 315 · H315-H319-H335
- Precautionary statements
- 261 · P261-P264-P271-P280-P302+P352-P305+P351+P338
- target organs
- Respiratory system
- PPE
- 95 · dust mask type N95 (US), Eyeshields, Gloves
- Hazard Codes
- Xi
- Risk Statements
- 36 · 36/37/38
- Safety Statements
- 26 · 26-36
- WGK Germany
- 3 · 3
- HS Code
- 2932.99 · 2932.99.9090
- HazardClass
- IRRITANT
- Storage Class
- 11 · 11 - Combustible Solids
- Hazard Classifications
- 2 Skin · Eye Irrit. 2Skin Irrit. 2STOT SE 3
Safety & regulation
GHS classification
GHS Classification
Warning
H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]
P261, P264, P264+P265, P271, P280, P302+P352, P304+P340, P305+P351+P338, P319, P321, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501 (click each P-code to see the statement)
Aggregated GHS information provided per 41 reports by companies from 4 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.
Hazard information
Safety data
- PPE
- dust mask type N95 (US), Eyeshields, Gloves
- wgk
- 3
- hs_code
- 2932.99.9090
- risk_code
- 36/37/38
- Signal word
- Warning
- Symbol(GHS)
- GHS07
- hazard_code
- Xi
- safety_code
- 26-36
- hazard_class
- IRRITANT
- Storage Class
- 11 - Combustible Solids
- target organs
- Respiratory system
- Hazard statements
- H315-H319-H335
- Hazard Classifications
- Eye Irrit. 2Skin Irrit. 2STOT SE 3
- Precautionary statements
- P261-P264-P271-P280-P302+P352-P305+P351+P338
Chemistry & industry
Applications
Uses2-Amino-3-formylchromone may be used in the preparation of the following:chiral Schiff base ligands (R)/(S)-2-amino-3-(((1-hydroxypropan-2-yl)imino)methyl)-4H-chromen-4-onehydrazone derivatives, required for the synthesis of heterocyclic Schiff′s bases having antimicrobial activityN-{4-[(6-chloro-4-oxo-4H-chromen-3-ylmethylene)amino]phenyl}-3,5-dimethyl-benzofuran-2-carboxamideN-{4-[(6-chloro-4-oxo-4H-chromen-3-ylmethylene)amino]phenyl}-1,4-dihydro-chromono [2,3-b]pyrrole-2-carboxamide6-chloro-3-{[4-(2-thioxo-3,6-dihydro-2H-1,3,4-thiadiazin-5-ylamino)phenylimino] methyl}- 4-oxo-4H -chromene3--(2-amino--4--oxo--4H--chromen--3--yl)methylidene)--6-- ethyl--2H--pyrano[3,2--c]quinolone--2,4,5(3H,6H)-trione
General Description2-Amino-3-formylchromone (2-Amino-4-oxo-4H-1-benzopyran-3-carboxaldehyde) is a benzopyran derivative. It is a bicyclic heterocyclic molecule made up of a benzene ring fused to a heterocyclic pyran ring. It undergoes condensation with (R)-2-amino-2-phenylethanol to afford Schiff base ligand, which forms complexes with Cu(NO3)2 and Zn(NO3)2.
Upstream & downstream products
Downstream products
Suppliers57 total
Related reactions
Compound notes
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