Basic information
- CAS
66300-61-6- Standard SMILES
FC(F)(F)COc1ccc(OCC(F)(F)F)cc1- InChIKey
ZHUBFESHPMGIDZ-UHFFFAOYSA-N- Molecular formula
- C10H8F6O2
- Average molar mass
- 274.16 g/mol
- Monoisotopic mass
- 274.04284882
Names & identifiers
- Preferred name
- 1,4-Bis(2,2,2-trifluoroethoxy)benzene
- IUPAC
- 1,4-bis(2,2,2-trifluoroethoxy)benzene
- English name
- 1,4-Di(2,2,2-trifluoroethoxy)benzene
- Molecular formula
- C10H8F6O2
- Molecular weight
- 274.16
Names & synonyms
1,4-Bis(2,2,2-trifluoroethoxy)benzene66300-61-6EINECS 266-304-2DTXSID90216517RefChem:73115DTXCID20139008266-304-2MFCD000422721,4-di(2,2,2-trifluoroethoxy)benzeneFlecainide Impurity 17SCHEMBL289505SCHEMBL498377
Show more names
Flecainide Impurity 3Benzene, 1,4-bis(2,2,2-trifluoroethoxy)-1,4-Bis(2,2,2-trifluoroethoxy)benzene97%1,4-Bis(2,2,2-trifluoroethoxy)benzene 97%1,4-DI(2,2,2-TRIFLUOROETHOXY)BENZENE 66300-61-61,4-Bis(2,2,2-Trifluoroethoxy)-Benzene （For Flecaintde）
CCG-4694CS-M0607AKOS0160014091,4-Di-(2,2,2-trifluoroethoxy)benzenePS-11082SY3166211,4-bis(2,2,2-trifluoroethoxy) benzene1,4-Bis-(2,2,2-trifluoroethoxy)benzene
Database identifiers
- CAS
66300-61-6- PubChem CID
- 737156
- DTXSID
DTXSID90216517- EC Number
- 266-304-2
- Nikkaji
- J286.759A
Properties
Computed structural properties
- XLogP
- 4.1
- Topological polar surface area
- 18.5 Ų
- Hydrogen bond donors
- 0
- Hydrogen bond acceptors
- 8
- Rotatable bonds
- 4
- Heavy atoms
- 18
- Formal charge
- 0
- Complexity
- 216
Experimental & physicochemical properties
PFASPFAS -> PFAS identified in REACH Regulation EC No. 1272/2008
Physicochemical properties
- Melting point
- 71 · 71-73°C
- Boiling point
- 111 · 111-112°C/10mm
- Density
- 1.348 · 1.348±0.06 g/cm3(Predicted)
- storage temp.
- Sealed in dry,Room Temperature
- Appearance
- White to off-white Solid
- BRN
- 4464913 · 4464913
- CAS DataBase Reference
- 66300 · 66300-61-6(CAS DataBase Reference)
- Symbol(GHS)
- 7 · GHS07
- Signal word
- Warning
- Hazard statements
- 302 · H302-H315-H319-H335
- Precautionary statements
- 261 · P261-P280-P301+P312-P302+P352-P305+P351+P338
- Hazard Codes
- Xn
Safety & regulation
Safety information is for reference only and does not replace the supplier’s Safety Data Sheet (SDS), applicable regulations, or professional assessment.
GHS classification
GHS Classification
Warning
H302 (100%): Harmful if swallowed [Warning Acute toxicity, oral]
P261, P264, P264+P265, P270, P271, P280, P301+P317, P302+P352, P304+P340, P305+P351+P338, P319, P321, P330, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501 (click each P-code to see the statement)
Aggregated GHS information provided per 5 reports by companies from 2 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.
Hazard information
Regulatory InformationStatus: Active Update: 25-01-2019 https://echa.europa.eu/registration-dossier/-/registered-dossier/26181
Hazard Classes and CategoriesAcute Tox. 4 (100%)
Safety data
- hs_code
- 2906290090
- risk_code
- 22-36/37/38
- Signal word
- Warning
- Symbol(GHS)
- GHS07
- hazard_code
- Xn
- hazard_note
- Harmful
- safety_code
- 22-26-36/37/39
- Hazard statements
- H302-H315-H319-H335
- REACH Registrations
- Active
- Precautionary statements
- P261-P280-P301+P312-P302+P352-P305+P351+P338
Chemistry & industry
Applications
Uses1,4-Bis(2,2,2-trifluoroethoxy)benzene is useful in ligand design for Cu-Catalyzed Coupling Reactions.
Suppliers65 total
Hebei Chuanghai Biotechnology Co., Ltd+86-17732866630 · [email protected]
毕佳索（上海毕得医药科技股份有限公司）400-6005915 · [email protected]
成都翔才医药科技有限公司13683497877
T&W GROUP021-61551611 13296011611 · [email protected]
Dayang Chem (Hangzhou) Co.,Ltd.+86-0571-88938639 17705817739 · [email protected]
安耐吉化学&3A（安徽泽升科技股份有限公司）400-0056266 · [email protected]
武汉凯威斯科技有限公司86-027-67849912 · [email protected]
广东元丰化学试剂有限公司0751-2829979 13318593351 · [email protected]
上海泰坦科技股份有限公司400-6009262 15618770481 · [email protected]
常州新星联生物科技有限公司0519-85556579 13376258932 · [email protected]
武汉丰泰威远科技有限公司+86-27-8746-5837 +86-18627785180 · [email protected]
武汉丰泰威远科技有限公司027-87465837 19945049750 · [email protected]
Related reactions
30 records
Compound notes
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