CAS 1483-72-3 Diphenyliodonium chloride (HCID 73870)

Names & identifiers

Preferred name: Diphenyliodonium chloride
IUPAC: diphenyliodanium chloride
English name: Diphenyliodonium chloride
Molecular formula: C12H10I.Cl
Molecular weight: 316.57

Names & synonyms

Diphenyliodonium chloride1483-72-3Iodonium, diphenyl-, chloride (1:1)Iodonium, diphenyl-, chloride72R2L86CXADTXSID60883679NSC-134275RefChem:134686DTXCID001023184216-049-8diphenyliodanium chloridediphenyliodanium;chloride

Show more names

DiphenyliodoniumDiphenyliodiniumchlorodiphenyliodoniumdiphenyl-iodoniuchlorideDiphenyliodinium chlorideIodonium,diphenyl-chlorideIodonium,diphenyl-,chlorideDiphenyliodoniumChloride>

MFCD00011909CHEMBL481680NSC 134275DiphenyliodoniumchlorideDiphenyl iodonium chlorideEINECS 216-049-8C12H10ClIAI3-17092

Database identifiers

CAS: 1483-72-3
PubChem CID: 73870
DTXSID: DTXSID60883679
ChEMBL: CHEMBL481680
UNII: 72R2L86CXA
EC Number: 216-049-8

Properties

Computed structural properties

Topological polar surface area: 0 Å²
Hydrogen bond donors: 0
Hydrogen bond acceptors: 1
Rotatable bonds: 2
Heavy atoms: 14
Formal charge: 0
Complexity: 116

Physicochemical properties

Melting point: 233 · 233-235 °C (subl.) (lit.)
Density: 1.6151 · 1.6151 (estimate)
storage temp.: Keep in dark place,Sealed in dry,Room Temperature
solubility: soluble in Methanol
form: Powder
color: White to light cream-yellow
Water Solubility: Soluble in water and methanol.
Sensitive: Light Sensitive
Merck: 14 · 14,7464
BRN: 3574977 · 3574977
InChI: InChI=1S/C12H10I.ClH/c1-3-7-11(8-4-1)13-12-9-5-2-6-10-12;/h1-10H;1H/q+1;/p-1
InChIKey: RSJLWBUYLGJOBD-UHFFFAOYSA-M
SMILES: [I+](C1C=CC=CC=1)C1C=CC=CC=1.[Cl-]
CAS DataBase Reference: 1483 · 1483-72-3(CAS DataBase Reference)
EPA Substance Registry System: Iodonium, diphenyl-, chloride (1483-72-3)
UNSPSC Code: 12352002 · 12352002
NACRES: 22 · NA.22
Symbol(GHS): 6 · GHS06
Signal word: Danger
Hazard statements: 301 · H301-H315-H319-H335
Precautionary statements: 301 · P301+P310+P330-P302+P352-P305+P351+P338
target organs: Respiratory system
PPE: 2 · Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges
Hazard Codes: T,Xi
Risk Statements: 25 · 25-36/37/38
Safety Statements: 26 · 26-36
RIDADR: 2811 · UN 2811 6.1/PG 3
WGK Germany: 3 · 3
RTECS: 6651666 · NN6651666
F: 8 · 8
TSCA: TSCA listed
HazardClass: 6.1 · 6.1
PackingGroup: III
HS Code: 29319090 · 29319090
Storage Class: 6.1 C · 6.1C - Combustible acute toxic Cat.3toxic compounds or compounds which causing chronic effects
Hazard Classifications: 3 OralEye · Acute Tox. 3 OralEye Irrit. 2Skin Irrit. 2STOT SE 3

Safety & regulation

GHS classification

GHS Classification · 4 items

Danger

H301 (100%): Toxic if swallowed [Danger Acute toxicity, oral]

P261, P264, P264+P265, P270, P271, P280, P301+P316, P302+P352, P304+P340, P305+P351+P338, P319, P321, P330, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501 (click each P-code to see the statement)

Aggregated GHS information provided per 47 reports by companies from 7 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

Hazard information

Regulatory InformationIodonium, diphenyl-, chloride: Does not have an individual approval but may be used under an appropriate group standard

Hazard Classes and CategoriesAcute Tox. 3 (100%)

Safety data

F: 8
PPE: Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges
wgk: 3
tsca: TSCA listed
rtecs: NN6651666
ridadr: UN 2811 6.1/PG 3
hs_code: 29319090
risk_code: 25-36/37/38
Signal word: Danger
Symbol(GHS): GHS06
hazard_code: T,Xi
safety_code: 26-36
hazard_class: 6.1
Storage Class: 6.1C - Combustible acute toxic Cat.3toxic compounds or compounds which causing chronic effects
packing_group: III
target organs: Respiratory system
Hazard statements: H301-H315-H319-H335
Hazard Classifications: Acute Tox. 3 OralEye Irrit. 2Skin Irrit. 2STOT SE 3
Precautionary statements: P301+P310+P330-P302+P352-P305+P351+P338

Chemistry & industry

Pharmacology

MeSH Pharmacological ClassificationSubstances that prevent infectious agents or organisms from spreading or kill infectious agents in order to prevent the spread of infection.

Uses & manufacturing

General Manufacturing InformationIodonium, diphenyl-, chloride (1:1): ACTIVE

Applications · 2 items

UsesDiphenyliodonium chloride is used as a reagent for electrophilic phenylation . It is used as a reactant for copper-catalyzed cross coupling reactions of purinesband arylation of anilines. It is involved in the preparation of acetylenic arylselenide and (arylmethylene)oxindoles. Further, it is employed in the preparation of aryl alkynes through Sonogashira coupling reactions.

UsesReactant for:Copper-catalyzed cross coupling reactions of purines and diaryliodonium saltsSynthesis of acetylenic arylselenidesSonogashira coupling reactions for the preparation of aryl alkynesC-H functionalization for synthesis of (arylmethylene)oxindolesArylation of anilinesStudies on the visible-light photosensitive system-dlourescein yellow-bis(di-Ph iodonium)Investigating the properties of direct and sensitized photolysis of dispersed photoacid generators