2,6-Difluoropyridine

HCID 73934CAS 1513-65-1
Substructure searchFind similar structures

Basic information

Standard SMILES
Fc1cccc(F)n1
InChIKey
MBTGBRYMJKYYOE-UHFFFAOYSA-N
Molecular formula
C5H3F2N
Average molar mass
115.08 g/mol
Monoisotopic mass
115.02335554

Overview

structure in first source

Names & identifiers

Preferred name
2,6-Difluoropyridine
IUPAC
2,6-difluoropyridine
English name
2,6-Difluoropyridine
Molecular formula
C5H3F2N
Molecular weight
115.08

Names & synonyms

2,6-DIFLUOROPYRIDINE1513-65-1Pyridine, 2,6-difluoro-NSC-331814Y58NXZ62TVDTXSID80164755RefChem:83240DTXCID4087246216-152-8MFCD000062272,6-difluorpyridinCCRIS 1720
Show more names
2,6-DifL2,6-difluoropyridi2,6-Difuloropyridine2,6-Difluoropyridine99%2,6-Difluoropyridine 99%2, 6-2 fluoride pyridine2,6-Difluoropyridine >
2,6-Difluoro-pyridineNSC 331814NSC3318142,6-difluoropyridin2,6 Difluoropyridine2, 6-difluoropyridine2,6 difluoro pyridine2,6-di-fluoropyridine

Database identifiers

CAS
1513-65-1
PubChem CID
73934
DTXSID
DTXSID80164755
ChEMBL
CHEMBL449478
UNII
Y58NXZ62TV
EC Number
216-152-8
Nikkaji
J149.539I

Properties

Computed structural properties

XLogP
1.2
Topological polar surface area
12.9 Ų
Hydrogen bond donors
0
Hydrogen bond acceptors
3
Rotatable bonds
0
Heavy atoms
8

Experimental & physicochemical properties

SpringerMaterials PropertiesCoriolis coupling

Physicochemical properties

Boiling point
124.5 °C/743 · 124.5 °C/743 mmHg (lit.)
Density
1.268 g/mL · 1.268 g/mL at 25 °C (lit.)
refractive index
20 · n20/D 1.437(lit.)
Flash point
93 °F · 93 °F
storage temp.
2 · Inert atmosphere,2-8°C
solubility
Not miscible or difficult to mix.

Safety & regulation

GHS classification

GHS Classification · 4 items

Warning

H226 (100%): Flammable liquid and vapor [Warning Flammable liquids]

P210, P233, P240, P241, P242, P243, P261, P264, P264+P265, P271, P280, P302+P352, P303+P361+P353, P304+P340, P305+P351+P338, P319, P321, P332+P317, P337+P317, P362+P364, P370+P378, P403+P233, P403+P235, P405, and P501 (click each P-code to see the statement)

Aggregated GHS information provided per 50 reports by companies from 10 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

Hazard information

Regulatory Information2,6-Difluoropyridine: Does not have an individual approval but may be used under an appropriate group standard
Hazard Classes and CategoriesFlam. Liq. 3 (100%)

Safety data

F
10
PPE
Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter
wgk
3
ridadr
UN 1993 3/PG 3
hs_code
29333999
risk_code
10-36/37/38

Chemistry & industry

Applications · 2 items

Uses2,6-Difluoropyridine has been used in the preparation of poly(pyridine ether)s via polycondensation with silylated 1,1,1-tris(4-hydroxyphenyl)ethane.

General DescriptionLithium diisopropylamide (LDA)-mediated ortholithiations of 2,6-difluoropyridine in tetrahydrofuran at -78°C has been studied using a combination of IR and NMR spectroscopic and computational methods. Polycondensation of bistrimethylsilyl derivatives of various diphenols with 2,6-difluoropyridine in N-methylpyrrolidone in the presence of K2CO3 has been investigated.

Upstream & downstream products

Suppliers50 total

国药集团化学试剂有限公司86-21-63210123 · [email protected]
梯希爱(上海)化成工业发展有限公司021-67121386 · [email protected]
衢州润东化工有限公司0570-8789886 18892685668 · [email protected]
上海阿拉丁生化科技股份有限公司400-6206333 13167063860 · [email protected]
T&W GROUP021-61551611 13296011611 · [email protected]

Related reactions

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Linked notes

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