2-Methoxypyridine
Basic information
- CAS
1628-89-3- Standard SMILES
COc1ccccn1- InChIKey
IWTFOFMTUOBLHG-UHFFFAOYSA-N- Molecular formula
- C6H7NO
- Average molar mass
- 109.13 g/mol
- Monoisotopic mass
- 109.05276384
Names & identifiers
- Preferred name
- 2-Methoxypyridine
- IUPAC
- 2-methoxypyridine
- English name
- 2-Methoxypyridine
- Molecular formula
- C6H7NO
- Molecular weight
- 109.13
Names & synonyms
2-METHOXYPYRIDINE1628-89-3Pyridine, 2-methoxy-GEB38J8108EINECS 216-623-8AI3-62040FEMA NO. 4639DTXSID60862722Pyridine, 2methoxyRefChem:474684DTXCID10811447216-623-8
Show more names
2-Methoxyl pyridine2-Methoxypyridine>2-Methoxypyridine98%2-Methoxypyridine 99%2-Pyridol methyl etherMETHYL 2-PYRIDYL ETHERMethyl pyridin-2-yl ether2-METHOXY PYRIDINE FEMA NO.--------2-Methoxypyridine ISO 9001：2015 REACH
InChI=1/C6H7NO/c1-8-6-4-2-3-5-7-6/h2-5H,1HPyridine, methoxy-2-methoxy-pyridineMFCD0000626293337-21-4methoxypyridineUNII-GEB38J81086-methoxypyridine
Database identifiers
- CAS
1628-89-3、93337-21-4- PubChem CID
- 74201
- DTXSID
DTXSID60862722- ChEMBL
CHEMBL3274300- UNII
- GEB38J8108
- EC Number
- 216-623-8
- Nikkaji
- J7.535C
Properties
Computed structural properties
- XLogP
- 1.4
- Topological polar surface area
- 22.1 Ų
- Hydrogen bond donors
- 0
- Hydrogen bond acceptors
- 2
- Rotatable bonds
- 1
- Heavy atoms
- 8
- Formal charge
- 0
- Complexity
- 65.5
Experimental & physicochemical properties
Chemical ClassesNitrogen Compounds -> Pyridines
SpringerMaterials Properties15N nuclear magnetic resonance spectrum
LogP1.23
Food AdditivesFLAVORING AGENT OR ADJUVANT -> FDA Substance added to food
Density1.044-1.050 (20º)
Solubility
Practically insoluble to insoluble in water
Soluble (in ethanol)
Boiling Point142-144º
Vapor Pressure2.58 [mmHg]
Refractive Index1.501-1.507
Physical Description
Colorless liquid; [Alfa Aesar MSDS]
Colourless to pale yellow liquid; green fermented tea-like aroma
Safety & regulation
Safety information is for reference only and does not replace the supplier’s Safety Data Sheet (SDS), applicable regulations, or professional assessment.
GHS classification
GHS Classification
Warning
H226 (100%): Flammable liquid and vapor [Warning Flammable liquids]
P210, P233, P240, P241, P242, P243, P261, P264, P264+P265, P271, P280, P302+P352, P303+P361+P353, P304+P340, P305+P351+P338, P319, P321, P332+P317, P337+P317, P362+P364, P370+P378, P403+P233, P403+P235, P405, and P501 (click each P-code to see the statement)
Aggregated GHS information provided per 46 reports by companies from 5 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.
Hazard information
Hazards SummaryA skin and strong eye irritant; [Alfa Aesar MSDS] See Pyridine.
Hazard Classes and CategoriesFlam. Liq. 3 (100%)
Safety data
- PPE
- Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter
- wgk
- 3
- ridadr
- UN 1993 3/PG 3
- hs_code
- 29339900
- risk_code
- 10-36/37/38
- Signal word
- Warning
- Symbol(GHS)
- GHS02,GHS07
- hazard_code
- Xi,F
- safety_code
- 26-36-16
- hazard_class
- 3
- Storage Class
- 3 - Flammable liquids
- packing_group
- III
- target organs
Chemistry & industry
Uses & manufacturing
Use Classification
Flavouring Agent -> FLAVOURING_AGENT -> JECFA Functional Classes
Flavoring Agents -> JECFA Flavorings Index
Applications
Uses2-Methoxypyridine can be used as an intermediate to synthesize 2-methoxy-3-pyridinesulfonyl chloride which is patented as a reactant used to prepare erythromycin macrolide antibiotics as antibacterial and antiprotozoal agents. It can also be used to prepare bicyclic iminopyrimidinones as Beta Amyloid Cleaving Enzyme-1 (BACE1) inhibitors.
Upstream & downstream products
Upstream raw materials
Downstream products
Related reactions
80 records
Compound notes
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