1,3,2-Benzodioxaphosphole, 2-chloro-

HCID 74232
NotesReactions
Substructure searchFind similar structures

Basic information

CAS
1641-40-3
Standard SMILES
ClP1Oc2ccccc2O1
InChIKey
YUJYEGDMJZHLMY-UHFFFAOYSA-N
Molecular formula
C6H4ClO2P
Average molar mass
174.52 g/mol
Monoisotopic mass
173.96374368

Names & identifiers

Preferred name
1,3,2-Benzodioxaphosphole, 2-chloro-
IUPAC
2-chloro-1,3,2-benzodioxaphosphole
English name
1,2-Phenylene phosphorochloridite
Molecular formula
C6H4ClO2P
Molecular weight
174.52

Names & synonyms

1641-40-3o-Phenylene phosphorochloridite2-Chloro-1,3,2-benzodioxaphosphole1,3,2-Benzodioxaphosphole, 2-chloro-EINECS 216-690-3DTXSID3061843RefChem:412275DTXCID8035269216-690-3InChI=1/C6H4ClO2P/c7-10-8-5-3-1-2-4-6(5)9-10/h1-41,2-Phenylene phosphorochloriditeo-Phenylene chlorophosphite
Show more names
2-chlorobenzo[d][1,3,2]dioxaphospholeCATECHYL PHOSPHORUS CHLORIDE2-benzodioxaphosphole,2-chloro-3Pyrocatechol phosphoryl chlorideChloro(1,2-phenylenedioxy)phosphineo-Phenylene phosphorochloridite,97%
1,2-phenylenephosphorochloridite2-chloro-2H-1,3,2-benzodioxaphosphole1,2-Phenylene Phosphorochloridite (Technical Grade)C6H4ClO2P2-Chloro-4,5-benzo-1,3,2-dioxaphospholaneSCHEMBL6975SCHEMBL30759806MFCD00005853

Database identifiers

CAS
1641-40-3
PubChem CID
74232
DTXSID
DTXSID3061843
EC Number
216-690-3
Nikkaji
J5.192F

Properties

Computed structural properties

XLogP
2.5
Topological polar surface area
18.5 Ų
Hydrogen bond donors
0
Hydrogen bond acceptors
2
Rotatable bonds
0
Heavy atoms
10

Experimental & physicochemical properties

SpringerMaterials PropertiesSchoenflies notation

Physicochemical properties

Melting point
30 · 30-35 °C(lit.)
Boiling point
80 °C20 · 80 °C20 mm Hg(lit.)
Density
1.466 g/mL · 1.466 g/mL at 25 °C(lit.)
refractive index
20 · n20/D 1.571(lit.)
Flash point
230 °F · >230 °F
storage temp.
0 · 0-6°C

Safety & regulation

GHS classification

GHS Classification · 4 items

Danger

H314 (100%): Causes severe skin burns and eye damage [Danger Skin corrosion/irritation]

P260, P264, P280, P301+P330+P331, P302+P361+P354, P304+P340, P305+P354+P338, P316, P321, P363, P405, and P501 (click each P-code to see the statement)

Aggregated GHS information provided per 43 reports by companies from 2 notifications to the ECHA C&L Inventory.

Hazard information

Regulatory InformationChemical: 1,3,2-Benzodioxaphosphole, 2-chloro-
Other Safety InformationEvaluation - Chemicals not considered for in depth evaluation - Not commercially active in Australia
Hazard Classes and CategoriesSkin Corr. 1B (100%)

Safety data

F
10-21
PPE
Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges
wgk
3
tsca
TSCA listed
ridadr
UN 3261 8/PG 2
risk_code
34

Chemistry & industry

Uses & manufacturing

General Manufacturing Information1,3,2-Benzodioxaphosphole, 2-chloro-: INACTIVE
Applications · 2 items

UsesHighly reactive cyclic phosphitylating reagent which provides fast coupling rates, and hydrolytic cleavage occurs more readily than with acyclic analogs

UsesCatalyst in synthesis of bakkane sesquiterpenesReactant in reversible halogen-halogen ligand substitution at room temperature, and in irreversible halogen-O substitution at higher temperaturesReactant in preparation of gold(I) trimethoxybenzonitrile phosphine isolated precatalystsReactant for preparation of pyrroles by TMSOTf-catalyzed Arbuzov reactionPhosphorylation agentReactant for reparation of vinyl-substituted spirophosphoranes and vinylphosphonates via Markovnikov addition

Suppliers25 total

Career Henan Chemica Co+86-0371-86658258 +86-13203830695 · [email protected]
Syntechem Co.,Ltd[email protected]
上海迈瑞尔生化科技有限公司4006356688 18621169109 · [email protected]
武汉易泰科技有限公司上海分公司18930552037 · [email protected]
阿法埃莎（中国）化学有限公司400-6106006 · [email protected]

Related reactions

1 records
New reaction record

Compound notes

Loading…