Basic information
- CAS
1772-03-8- Standard SMILES
Cl.N[C@@H](C=O)[C@@H](O)[C@@H](O)[C@H](O)CO- InChIKey
CBOJBBMQJBVCMW-NQZVPSPJSA-N- Molecular formula
- C6H14ClNO5
- Average molar mass
- 215.63 g/mol
- Monoisotopic mass
- 215.0560502
Overview
See also: D-Galactosamine (annotation moved to); aldehydo-D-galactosamine (annotation moved to).
Names & identifiers
- Preferred name
- Galactosamine hydrochloride
- IUPAC
- (2R,3R,4R,5R)-2-amino-3,4,5,6-tetrahydroxyhexanal;hydrochloride
- English name
- D(+)-Galactosamine hydrochloride
- Molecular formula
- C6H14ClNO5
- Molecular weight
- 215.63
Names & synonyms
1772-03-8D-Galactosamine hydrochlorideChondrosamine hydrochlorideD-Galactose, 2-amino-2-deoxy-, hydrochloride (1:1)2-Amino-2-deoxy-D-galactose hydrochlorideEINECS 217-198-1Galactose, 2-amino-2-deoxy-, hydrochloride, D-U51H7Z9859AI3-51895UNII-U51H7Z9859D-GALACTOSAMINE HYDROCHLORIDE [MI]GALACTOSAMINE HYDROCHLORIDE (USP-RS)
Show more names
GalactosamineGALACTOSAMINE HCLD-GalND-GALACTOSAMINE HCL2-Amino-2-Deoxy-D-Galactopyranose(3R,4R,5R,6R)-3-aMino-6-(hydroxyMethyl)tetrahydro-2H-pyran-2,4,5-triol hydrochlorideD-GALN HCL
GALACTOSAMINE HYDROCHLORIDE [USP-RS]2-AMINO-2-DEOXY-D-GALACTOSE, HYDROCHLORIDERefChem:142133217-198-1DTXCID2011356DTXSID4031356GALACTOSAMINE HYDROCHLORIDE(2R,3R,4R,5R)-2-amino-3,4,5,6-tetrahydroxyhexanal hydrochloride
Database identifiers
- CAS
Properties
Computed structural properties
- Topological polar surface area
- 124 Ų
- Hydrogen bond donors
- 6
- Hydrogen bond acceptors
- 6
- Rotatable bonds
- 5
- Heavy atoms
- 13
- Formal charge
- 0
- Complexity
- 142
Physicochemical properties
- Melting point
- 182 · 182-185 °C (dec.)(lit.)
- alpha
- 96 · 96 º (589nm c=1,H2O,24 hrs)
- Density
- 1.3965 · 1.3965 (rough estimate)
- refractive index
- 96 ° · 96 ° (C=1, H2O)
- storage temp.
- room temp
- solubility
- 2 O: · H2O: 50 mg/mL, clear, colorless
- form
- White solid
- color
- White to Off-White
- biological source
- fish cartilage (shark)
- Water Solubility
- SOLUBLE
- Sensitive
- Hygroscopic
- Merck
- 14 · 14,4334
- BRN
- 3697825 · 3697825
- Stability
- Moisture Sensitive
- InChI
- 1S/C6H13NO5.ClH/c7-3(1-8)5(11)6(12)4(10)2-9;/h1,3-6,9-12H,2,7H2;1H/t3-,4+,5+,6-;/m0./s1
- InChIKey
- CBOJBBMQJBVCMW-NQZVPSPJSA-N
- SMILES
Safety & regulation
Safety information is for reference only and does not replace the supplier’s Safety Data Sheet (SDS), applicable regulations, or professional assessment.
GHS classification
GHS Classification
This chemical does not meet GHS hazard criteria for 88.9% (8 of 9) of all reports.
Warning
H319 (11.1%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]
P264+P265, P280, P305+P351+P338, and P337+P317 (click each P-code to see the statement)
Aggregated GHS information provided per 9 reports by companies from 2 notifications to the ECHA C&L Inventory.
Hazard information
Regulatory InformationD-Galactose, 2-amino-2-deoxy-, hydrochloride: Does not have an individual approval but may be used under an appropriate group standard
Hazard Classes and CategoriesEye Irrit. 2A (11.1%)
Safety data
- F
- 3-10
- PPE
- Eyeshields, Gloves, type N95 (US)
- wgk
- 3
- tsca
- TSCA listed
- rtecs
- LW5500000
- hs_code
- 29329970
- risk_code
- 36/37/38
- Signal word
- Warning
- Symbol(GHS)
- GHS07
- hazard_code
- Xi
- safety_code
- 24/25-36/37/39-27-26
- Storage Class
- 11 - Combustible Solids
- Hazard statements
- H302
Chemistry & industry
Uses & manufacturing
General Manufacturing InformationD-Galactose, 2-amino-2-deoxy-, hydrochloride (1:1): ACTIVE
Applications
UsesD-(+)-Galactosamine (D-chondrosamine) is used with lipopolysaccharides (LPS) to induce models of acute hepatic failure (LPS/D-GalN-induced liver injury, hepatitis) for therapeutic research to find new drugs.
UsesD-(+)-Galactosamine hydrochloride has been used to:induce livery injury inflammatory liver injury acute liver failure (ALF) in mice
UsesSpecifically inhibits COX-2 by preventing COX-2 N-glycosylation and by increasing COX-2 protein turnover in a proteasome-dependent manner.
General DescriptionPharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards
Suppliers100 total
山东玖玥生物科技有限公司15553333686 · [email protected]
国药集团化学试剂有限公司86-21-63210123 · [email protected]
北京华美互利生物化工010-56205725 · [email protected]
梯希爱(上海)化成工业发展有限公司021-67121386 · [email protected]
衢州润东化工有限公司0570-8789886 18892685668 · [email protected]
苏州合生源生物医药科技有限公司13918488572 · [email protected]
Related reactions
0 records
No reaction records under the current filter.
Compound notes
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