Basic information
- CAS
2002-24-6- Standard SMILES
Cl.NCCO- InChIKey
PMUNIMVZCACZBB-UHFFFAOYSA-N- Molecular formula
- C2H7NO.ClH
- Average molar mass
- 97.54 g/mol
- Monoisotopic mass
- 97.02944156
Overview
The CIR Expert Panel concluded that ethanolamine and the 12 related ethanolamine salts, listed below, are safe in the present practices of use and concentration described in this safety assessment (rinse-off products only) when formulated to be non-irritating. The Panel cautioned that ingredients should not be used in cosmetic products in which N-nitroso compounds may be formed...Ethanolamine HCl...
Names & identifiers
- Preferred name
- Ethanolamine Hydrochloride
- IUPAC
- 2-aminoethanol;hydrochloride
- English name
- Ethanolamine hydrochloride
- Molecular formula
- C2H8ClNO
- Molecular weight
- 97.54
Names & synonyms
2-Aminoethanol hydrochlorideEthanolamine hydrochloride2002-24-6Ethanolamine HCl2-Aminoethanol HClbeta-Aminoethanol hydrochlorideUNII-KKP3YYL02FKKP3YYL02FEINECS 217-900-6NSC 10000NSC 30601NSC 41218
Show more names
MONOETHANOLAMINE HYDROCHLORIDEETHANOLAMINE HYDROCH2-Aminoethan-1-ol hydrochloridemeahydrochlorideMONOETHANOLAMINE HCLethanolaminechloridecolaminehydrochlorideEthanolammoniumchlorid
NSC-10000NSC-30601NSC-41218DTXSID8049593ETHANOLAMINE HYDROCHLORIDE [II]ETHANOLAMINE HYDROCHLORIDE [MI]ETHANOLAMINE HYDROCHLORIDE (II)2Aminoethanol HCl
Database identifiers
- CAS
2002-24-6- PubChem CID
- 74819
- DTXSID
DTXSID8049593- UNII
- KKP3YYL02F
- EC Number
- 217-900-6
Properties
Computed structural properties
- Topological polar surface area
- 46.3 Ų
- Hydrogen bond donors
- 3
- Hydrogen bond acceptors
- 2
- Rotatable bonds
- 1
- Heavy atoms
- 5
- Formal charge
- 0
- Complexity
- 10
Experimental & physicochemical properties
Chemical ClassesNitrogen Compounds -> Ethanolamines
Cosmetics
Cosmetic ingredients (Ethanolamine HCl) -> CIR (Cosmetic Ingredient Review)
Buffering
Physical Description
Liquid
Deliquescent solid; [Merck Index] White hygroscopic powder; [Alfa Aesar MSDS]
Physicochemical properties
- Melting point
- 82 · 82-84 °C(lit.)
- Density
- 1.07 g/cm3 · 1.07g/cm3 at 20—25°C1.12g/cm3 at 20—25°C
- storage temp.
- 30 °C · Store below +30°C.
- solubility
- DMSO (Slightly, Heated)
- form
- Agglomerating Crystals
- Specific Gravity
- 1.146 · 1.146
- color
- White or slightly beige
- Odor
- Odorless
- PH
- 9 · 9—10
- pka
Safety & regulation
GHS classification
GHS Classification
This chemical does not meet GHS hazard criteria for 3.2% (7 of 220) of reports.
Warning
H290 (10%): May be corrosive to metals [Warning Corrosive to Metals]
P234, P261, P264, P264+P265, P270, P271, P273, P280, P301+P317, P302+P352, P304+P340, P305+P351+P338, P317, P319, P321, P330, P332+P317, P337+P317, P362+P364, P390, P403+P233, P405, P406, and P501 (click each P-code to see the statement)
Aggregated GHS information provided per 220 reports by companies from 15 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.
Hazard information
Regulatory Information
Chemical: Ethanol, 2-amino-, hydrochloride
Ethanol, 2-amino-, hydrochloride (1:1) is listed on the EPA's Chemical Data Reporting (CDR) system. Manufacturers and importers of Ethanol, 2-amino-, hydrochloride (1:1) are required to report information about their production and use of this chemical to the EPA under the Toxic Substances Control Act (TSCA). (40 eCFR Part 711)
Ethanol, 2-amino-, hydrochloride: Does not have an individual approval but may be used under an appropriate group standard
Other Safety InformationIMAP assessments - Ethanol, 2-amino-, hydrochloride: Human health tier I assessment
Hazards SummaryDecreased average litter size and increased post-implantation loss observed in 2-generation oral study of rats at doses maternally toxic (1,000 mg/kg/day); [EPA - TSCATS] A skin and strong eye irritant; [Alfa Aesar MSDS] See Ethanolamine.
Hazard Classes and CategoriesMet. Corr. 1 (10%)
Toxicology
Toxicity Summary
Chemistry & industry
Uses & manufacturing
Uses
CIR ingredient: Ethanolamine HCl
Used to remove carbon dioxide and hydrogen sulfide from natural gas and in the production of surfactants, antibiotics, polishes, hair waving solutions, and emulsifiers; Also used as a softening agent (hides) and dispersing agent (agricultural chemicals); [Merck Index]
Leather Tanning and Processing [Category: Industry]
U.S. Production2023: <75,000 lb
Industry UsesAnti-scaling agent
Use ClassificationCosmetics -> Buffering
General Manufacturing Information
Oil and Gas Drilling, Extraction, and Support activities
Ethanol, 2-amino-, hydrochloride (1:1): ACTIVE
Applications
UsesEthanolamine hydrochloride has been used:in overnight incubation of the tips to attach primary amine groups at the tip surfacein the preparation of DMEM (dulbecco′s modified eagle′s medium)/F-12 media to culture human epidermal growth factor receptor 2 (HER2) cells derived from MMTV-HER2 transgenic mouse mammary tumorsto administer the cultures to study its effect on the endogenous phosphatidyl ethanolamine pool and autophagy process
Upstream & downstream products
Upstream raw materials
Downstream products
Related reactions
20 records
Compound notes
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