Basic information
- CAS
100-22-1- Standard SMILES
CN(C)c1ccc(N(C)C)cc1- InChIKey
CJAOGUFAAWZWNI-UHFFFAOYSA-N- Molecular formula
- C10H16N2
- Average molar mass
- 164.25 g/mol
- Monoisotopic mass
- 164.13134852
Overview
Leaflets or a drab green solid. (NTP, 1992)
Names & identifiers
- Preferred name
- N,N,N',N'-tetramethyl-p-phenylenediamine
- IUPAC
- 1-N,1-N,4-N,4-N-tetramethylbenzene-1,4-diamine
- English name
- N,N,N',N'-Tetramethyl-1,4-phenylenediamine
- Molecular formula
- C10H16N2
- Molecular weight
- 164.25
Names & synonyms
100-22-1N,N,N',N'-TETRAMETHYL-P-PHENYLENEDIAMINEWurster's reagentTetramethyl-p-phenylenediaminep-Bis(dimethylamino)benzeneTL 85DTXSID5026124p-Phenylenediamine, N,N,N',N'-tetramethyl-P4P3AC32ZBTMPD (amine)Reagents, Wurster'sTMPPD
Show more names
N,N,N′,N′-Tetramethyl-p-phenylenediamineN1,N1,N4,N4-Tetramethylbenzene-1,4-diaminetl85WursterBlue]
N,N,N',N'-Tetramethyl-1,4-BenzenediamineDTXCID006124RefChem:926437202-831-6TMPDAn,n,n,n-tetramethyl-1,4-phenylenediamineWurster's BlueN,N,N',N'-Tetramethyl-1,4-phenylenediamine
Database identifiers
- CAS
100-22-1、27215-51-6- PubChem CID
- 7490
- DTXSID
DTXSID201370133- ChEMBL
CHEMBL1393325- UNII
- P4P3AC32ZB
- EC Number
- 202-831-6
Properties
Computed structural properties
- XLogP
- 2.6
- Topological polar surface area
- 6.5 Ų
- Hydrogen bond donors
- 0
- Hydrogen bond acceptors
- 2
- Rotatable bonds
- 2
- Heavy atoms
- 12
- Formal charge
- 0
- Complexity
- 108
Experimental & physicochemical properties
Chemical Classes
Nitrogen Compounds -> Amines, Aromatic
Nitrogen Compounds -> Amines, Aromatic
SpringerMaterials Properties15N nuclear magnetic resonance spectrum
Solubilityless than 1 mg/mL at 70 °F (NTP, 1992)
Flash Pointgreater than 235 °F (NTP, 1992)
Boiling Point500 °F at 760 mmHg (NTP, 1992)
Melting Point120 to 124 °F (NTP, 1992)
Vapor Pressure0.07 [mmHg]
Physical Description
Leaflets or a drab green solid. (NTP, 1992)
Solid; [Merck Index] Drab green solid; [NTP] Grey powder; [Sigma-Aldrich MSDS]
Physicochemical properties
Safety & regulation
Safety information is for reference only and does not replace the supplier’s Safety Data Sheet (SDS), applicable regulations, or professional assessment.
GHS classification
GHS Classification
Warning
H302: Harmful if swallowed [Warning Acute toxicity, oral]
P261, P264, P270, P271, P280, P301+P317, P302+P352, P304+P340, P317, P321, P330, P362+P364, and P501 (click each P-code to see the statement)
Warning
H302 (98%): Harmful if swallowed [Warning Acute toxicity, oral]
P261, P264, P270, P271, P280, P301+P317, P302+P352, P304+P340, P317, P321, P330, P362+P364, and P501 (click each P-code to see the statement)
Hazard information
Regulatory Information
Chemical: 1,4-Benzenediamine, N,N,N',N'-tetramethyl-
Tetramethyl-p-phenylenediamine: Does not have an individual approval but may be used under an appropriate group standard
Fire HazardsThis chemical is probably combustible. (NTP, 1992)
Health HazardsACUTE/CHRONIC HAZARDS: When heated to decomposition this compound emits toxic fumes. It is an irritant. (NTP, 1992)
Hazards Summary
Causes irritability and acute pulmonary edema in inhalation lethal-concentration studies of mice; [RTECS] May cause irritation; Toxic by inhalation; Harmful by ingestion and skin absorption; Targets the kidney; [Sigma-Aldrich MSDS] See N,N-Diethyl-p-phenylenediamine.
Reactive GroupAmines, Phosphines, and Pyridines
Reactivity Profile
N,N,N',N'-TETRAMETHYL-P-PHENYLENEDIAMINE can burn in air to give toxic NOx gases (NTP, 1992). Neutralizes acids in exothermic reactions to form salts plus water. May be incompatible with isocyanates, halogenated organics, peroxides, phenols (acidic), epoxides, anhydrides, and acid halides. Flammable gaseous hydrogen may be generated in combination with strong reducing agents, such as hydrides.
Chemistry & industry
Uses & manufacturing
Uses
Used as a reagent in analytical chemistry (in the hydrochloride form); [Merck Index]
The hydrochloride form is used as a reagent in analytical chemistry; [ChemIDplus]
General Manufacturing Information1,4-Benzenediamine, N1,N1,N4,N4-tetramethyl-: ACTIVE
Applications
UsesN,N,N',N'-Tetramethyl-p-phenylenediamine is a reducing co-substrate for heme peroxidases. It is used for detection of peroxidases on polyacrylamide gels.
UsesIn the form of the hydrochloride as a reagent in analytical chemistry.
General DescriptionLeaflets or a drab green solid.
Upstream & downstream products
Upstream raw materials
Suppliers1 total
苏州市森菲达化工有限公司18796480002 18796480002 · [email protected]
Related reactions
1 records
Compound notes
Loading…