Tetrahydro-4H-pyran-4-ol (HCID 74956)

Names & identifiers

Preferred name: Tetrahydro-4H-pyran-4-ol
IUPAC: oxan-4-ol
English name: Tetrahydro-4-pyranol
Molecular formula: C5H10O2
Molecular weight: 102.13

Names & synonyms

2081-44-9Tetrahydro-2H-pyran-4-oloxan-4-ol2H-Pyran-4-ol, tetrahydro-Tetrahydro-4H-pyran-4-olZZ9W8N9YQVEINECS 218-210-8DTXSID90174921RefChem:188629DTXCID9097412218-210-8LMYJGUNNJIDROI-UHFFFAOYSA-N

Show more names

POHTetrahydropyranol2H-Pyran-4-ol4-HYDROXYTETRAHYDROPYANTetrahydro-4-pranol

Tetrahydro-4-pyranoltetrahydropyran-4-ol4-HydroxytetrahydropyranTetrahydro-pyran-4-olMFCD000066334-hydroxytetrahydro-4h-pyrantetrahydro-pyran-4ol4-hydroxy tetrahydropyran

Database identifiers

CAS: 2081-44-9
PubChem CID: 74956
DTXSID: DTXSID90174921
UNII: ZZ9W8N9YQV
EC Number: 218-210-8
Nikkaji: J236.606A

Properties

Computed structural properties

XLogP: -0.1
Topological polar surface area: 29.5 Å²
Hydrogen bond donors: 1
Hydrogen bond acceptors: 2
Rotatable bonds: 0
Heavy atoms: 7
Formal charge: 0
Complexity: 48

Physicochemical properties

Boiling point: 87 °C/15 · 87 °C/15 mmHg (lit.)
Density: 1.071 g/mL · 1.071 g/mL at 25 °C (lit.)
refractive index: 20 · n20/D 1.462(lit.)
Flash point: 190 °F · 190 °F
storage temp.: Sealed in dry,Room Temperature
solubility: Chloroform, Methanol
form: Oil
pka: 14.61 · 14.61±0.20(Predicted)
color: Clear Colourless
BRN: 102736 · 102736
InChI: InChI=1S/C5H10O2/c6-5-1-3-7-4-2-5/h5-6H,1-4H2
InChIKey: LMYJGUNNJIDROI-UHFFFAOYSA-N
SMILES: C1OCCC(O)C1
LogP: -0.44 · -0.440 (est)
CAS DataBase Reference: 2081 · 2081-44-9(CAS DataBase Reference)
FDA UNII: 9 W8N9YQV · ZZ9W8N9YQV
NIST Chemistry Reference: -4 H-pyran-4-ol · Tetrahydro-4H-pyran-4-ol(2081-44-9)
UNSPSC Code: 12352100 · 12352100
NACRES: 22 · NA.22
Symbol(GHS): 5 · GHS05
Signal word: Danger
Hazard statements: 318 · H318
Precautionary statements: 280 · P280-P305+P351+P338
PPE: Eyeshields, Gloves, type ABEK (EN14387) respirator filter
Hazard Codes: Xi,Xn
Risk Statements: 41 · 41-36/37/38-20/22
Safety Statements: 26 · 26-39-36/37/39-23
RIDADR: 1993 · 1993
WGK Germany: 3 · 3
HazardClass: IRRITANT
HS Code: 29329990 · 29329990
Storage Class: 10 · 10 - Combustible liquids
Hazard Classifications: 1 · Eye Dam. 1
REACH Registrations: Active

Safety & regulation

GHS classification

GHS Classification · 4 items

Danger

H315 (10.2%): Causes skin irritation [Warning Skin corrosion/irritation]

P261, P264, P264+P265, P271, P280, P302+P352, P304+P340, P305+P351+P338, P305+P354+P338, P317, P319, P321, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501 (click each P-code to see the statement)

Aggregated GHS information provided per 49 reports by companies from 7 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

Hazard information

Regulatory InformationStatus: Active Update: 21-11-2017 https://echa.europa.eu/registration-dossier/-/registered-dossier/21179

Hazard Classes and CategoriesSkin Irrit. 2 (10.2%)

Safety data

PPE: Eyeshields, Gloves, type ABEK (EN14387) respirator filter
wgk: 3
ridadr: 1993
hs_code: 29329990
risk_code: 41-36/37/38-20/22
Signal word: Danger
Symbol(GHS): GHS05
hazard_code: Xi,Xn
safety_code: 26-39-36/37/39-23
hazard_class: IRRITANT
Storage Class: 10 - Combustible liquids
Hazard statements: H318
REACH Registrations: Active
Hazard Classifications: Eye Dam. 1
Precautionary statements: P280-P305+P351+P338

Chemistry & industry

Applications

UsesTetrahydro-4-pyranol (4-Hydroxytetrahydropyran) was used in the quantitative analysis of 3-hydroxytetrahydropyran (3-HTHP).

UsesTetrahydro-4-pyranol is a building block of various organic compounds and pharmaceuticals.

Upstream & downstream products

Upstream raw materials

Downstream products

4-BROMO-TETRAHYDROPYRAN 1-(Tetrahydro-2H-pyran-4-yl)hydrazine Tetrahydropyran-4-carbaldehyde 2-(tetrahydro-2H-pyran-4-yloxy)-5-(4,4,5,5-tetraMethyl-1,3,2-dioxaborolan-2-yl)benzonitrile 4-IODOTETRAHYDRO-2H-PYRAN Tetrahydropyranyl-4-acetic acid 3-Pyridinol, 5-chloro-6-[(tetrahydro-2H-pyran-4-yl)oxy]-

Suppliers50 total

梯希爱(上海)化成工业发展有限公司021-67121386 · [email protected]

衢州润东化工有限公司0570-8789886 18892685668 · [email protected]

上海阿拉丁生化科技股份有限公司400-6206333 13167063860 · [email protected]

T&W GROUP021-61551611 13296011611 · [email protected]

爱斯特（成都）生物制药股份有限公司+86-28-85122536 85324413 · [email protected]

Related reactions

312 records

New reaction record

HRID 1674As reactantuspto-grants-1998_03

HRID 23533As reactantuspto-grants-2005_02

HRID 29162As reactantuspto-grants-2008_09

HRID 39294As reactantuspto-grants-2013_09

HRID 57547As reactantuspto-grants-2016_09

HRID 61697As reactantuspto-grants-2016_09

HRID 64286As reactantuspto-grants-2016_09

HRID 70631As reactantuspto-grants-2014_09

Linked notes

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Basic information