Basic information
- CAS
18135-05-2- Standard SMILES
CN(C)[Si](C)(C)C- InChIKey
KAHVZNKZQFSBFW-UHFFFAOYSA-N- Molecular formula
- C5H15NSi
- Average molar mass
- 117.26 g/mol
- Monoisotopic mass
- 117.09737601
Names & identifiers
- Preferred name
- Pentamethylsilylamine
- IUPAC
- N-methyl-N-trimethylsilylmethanamine
- English name
- N,N-Dimethyltrimethylsilylamine
- Molecular formula
- C5H15NSi
- Molecular weight
- 117.26
Names & synonyms
2083-91-2N,N-DimethyltrimethylsilylamineN,N-DimethylaminotrimethylsilaneN-(Trimethylsilyl)dimethylaminePentamethylsilylamineSilanamine, pentamethyl-(Dimethylamino)trimethylsilaneTMSDMAN-methyl-N-trimethylsilylmethanamineSilanamine, N,N,1,1,1-pentamethyl-N,N,1,1,1-pentamethylsilanamineDimethylaminotrimethylsilane
Show more names
DK204CD5400pentamethyl-silanaminpentamethyl-SilanamineSilanamine,pentamethyl-
R5D6N5EJ26DTXSID7062168EINECS 218-222-3EINECS 242-020-4n,n-dimethyl-n-(trimethylsilyl)amineN,N-Dimethyl-1-(trimethylsilyl)amineN,N-DIMETHYL(TRIMETHYLSILYL)AMINEMethanamine, N-methyl-1-(trimethylsilyl)-
Database identifiers
- CAS
18135-05-2、2083-91-2- PubChem CID
- 74965
- DTXSID
DTXSID7062168- UNII
- R5D6N5EJ26
- EC Number
- 218-222-3
- Nikkaji
- J43.464G
Properties
Computed structural properties
- Topological polar surface area
- 3.2 Ų
- Hydrogen bond donors
- 0
- Hydrogen bond acceptors
- 1
- Rotatable bonds
- 1
- Heavy atoms
- 7
- Formal charge
- 0
- Complexity
- 53.6
Experimental & physicochemical properties
Chemical ClassesMetals -> Metalloid Compounds (Silicon)
SpringerMaterials Properties15N nuclear magnetic resonance spectrum
Physical DescriptionClear colorless liquid; [Sigma-Aldrich MSDS]
Physicochemical properties
- Melting point
- 0 °C · <0°C
- Boiling point
- 84 °C · 84 °C (lit.)
- Density
- 0.732 g/mL · 0.732 g/mL at 25 °C (lit.)
- refractive index
- 20 · n20/D 1.397(lit.)
- Flash point
- 3 °F · −3 °F
- storage temp.
- Flammables area
- form
- clear liquid
- pka
- 10.77 · 10.77±0.70(Predicted)
- Specific Gravity
- 0.74 · 0.74
- color
- Colorless to Light yellow
Safety & regulation
Safety information is for reference only and does not replace the supplier’s Safety Data Sheet (SDS), applicable regulations, or professional assessment.
GHS classification
GHS Classification
Danger
H225 (100%): Highly Flammable liquid and vapor [Danger Flammable liquids]
P210, P223, P231+P232, P233, P240, P241, P242, P243, P260, P264, P280, P301+P330+P331, P302+P335+P334, P302+P361+P354, P303+P361+P353, P304+P340, P305+P354+P338, P316, P321, P363, P370+P378, P402+P404, P403+P235, P405, and P501 (click each P-code to see the statement)
Aggregated GHS information provided per 139 reports by companies from 9 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.
Hazard information
Regulatory Information
Status: Active Update: 24-11-2022 https://echa.europa.eu/registration-dossier/-/registered-dossier/34239
Dimethylaminotrimethylsilane: HSNO Approval: HSR004445 Approved with controls
Hazards SummaryCauses burns; Inhalation may cause corrosive injuries to upper respiratory tract; [Sigma-Aldrich MSDS] See Hexamethyldisilazane and Bis(dimethylamino)dimethylsilane.
Hazard Classes and CategoriesFlam. Liq. 2 (100%)
Toxicology
Adverse EffectsDermatotoxin - Skin burns.
Safety data
- F
- 1-10
- PPE
- Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter
- wgk
- 3
- tsca
- TSCA listed
Chemistry & industry
Uses & manufacturing
General Manufacturing InformationSilanamine, N,N,1,1,1-pentamethyl-: ACTIVE
Applications
UsesN,N-Dimethyltrimethylsilylamine was used in the synthesis of phosphoramidite. It was also employed as a reagent in the preparation of iminium salts and amides as well as for the silylation of polymers. A combination of N-(trimethylsilyl)dimethylamine and MeI was also effective to give p-methylbenzoic acid with a 85% yield based on 90% conversion from the corresponding Me ester. DETA has been treated with N-(trimethylsilyl)-dimethylamine to yield mono-, di- and tri- silylated derivatives
Upstream & downstream products
Upstream raw materials
Downstream products
Suppliers
Related reactions
5 records
Compound notes
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