Basic information
- CAS
2344-80-1- Standard SMILES
C[Si](C)(C)CCl- InChIKey
OOCUOKHIVGWCTJ-UHFFFAOYSA-N- Molecular formula
- C4H11ClSi
- Average molar mass
- 122.67 g/mol
- Monoisotopic mass
- 122.03185456
Names & identifiers
- Preferred name
- Silane, (chloromethyl)trimethyl-
- IUPAC
- chloromethyl(trimethyl)silane
- English name
- Chloromethyltrimethylsilane
- Molecular formula
- C4H11ClSi
- Molecular weight
- 122.67
Names & synonyms
Chloromethyltrimethylsilane2344-80-1(Chloromethyl)trimethylsilaneSilane, (chloromethyl)trimethyl-EINECS 219-058-5DTXSID1062330EC 219-058-5RefChem:885126DTXCID3036864219-058-5(Trimethylsilyl)methyl chloridechloromethyl(trimethyl)silane
Show more names
DK684CC3285DKSI007DKSI166SILANE CMM3DKFELEX0172TRIMETHYLSILYLCHLOROMETHANE
C4H11ClSi(CH3)3SiCH2ClMFCD00000878Chloromethyl trimethylsilanechloromethyl-trimethyl-silaneS04425trimethylchloromethylsilanetrimethylsilylmethyl chloride
Database identifiers
- CAS
2344-80-1- PubChem CID
- 75361
- DTXSID
DTXSID1062330- EC Number
- 219-058-5
- Nikkaji
- J47.467C
Properties
Computed structural properties
- Topological polar surface area
- 0 Ų
- Hydrogen bond donors
- 0
- Hydrogen bond acceptors
- 0
- Rotatable bonds
- 1
- Heavy atoms
- 6
- Formal charge
- 0
- Complexity
- 37.3
Experimental & physicochemical properties
SpringerMaterials Properties29Si nuclear magnetic resonance spectrum
Physicochemical properties
- Melting point
- 0 °C · <0°C
- Boiling point
- 98 · 98-99 °C(lit.)
- Density
- 0.88 g/mL · 0.88 g/mL at 20 °C
- vapor pressure
- 25 mm · ~25 mm Hg ( 20 °C)
- refractive index
- 20 · n20/D 1.418(lit.)
- Flash point
- 27 °F · 27 °F
- storage temp.
- 30 °C · Store below +30°C.
- solubility
- soluble in Benzene, Methanol
- form
- Liquid
- Specific Gravity
- 0.879 · 0.879
- color
- Clear colorless
- Water Solubility
- insoluble
- Sensitive
- Moisture Sensitive
- Hydrolytic Sensitivity
- 4 · 4: no reaction with water under neutral conditions
- BRN
- 906705 · 906705
- InChI
- 1S/C4H11ClSi/c1-6(2,3)4-5/h4H2,1-3H3
- InChIKey
- OOCUOKHIVGWCTJ-UHFFFAOYSA-N
- SMILES
- C[Si](C)(C)CCl
- CAS DataBase Reference
- 2344 · 2344-80-1(CAS DataBase Reference)
- NIST Chemistry Reference
- Silane, (chloromethyl)trimethyl-(2344-80-1)
- EPA Substance Registry System
- Silane, (chloromethyl)trimethyl- (2344-80-1)
- UNSPSC Code
- 12352103 · 12352103
- NACRES
- 22 · NA.22
- Symbol(GHS)
- 2 · GHS02,GHS07
- Signal word
- Danger
- Hazard statements
- 302 · H302+H312+H332-H315-H319-H335-H225
- Precautionary statements
- 501 · P501-P270-P240-P261-P210-P233-P243-P241-P242-P271-P264-P280-P370+P378-P337+P313-P305+P351+P338-P362+P364-P303+P361+P353-P332+P313-P301+P312+P330-P304+P340+P312-P403+P233-P403+P235-P405
- target organs
- Respiratory system
- PPE
- Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter
- Hazard Codes
- F,Xi,C
- Risk Statements
- 11 · 11-36/37/38-34
- Safety Statements
- 16 · 16-26-36-29-37/39-33
- RIDADR
- 1993 · UN 1993 3/PG 2
- WGK Germany
- 3 · 3
- F
- 10 · 10-21
- Hazard Note
- Irritant/Highly Flammable
- TSCA
- TSCA listed
- HazardClass
- 3 · 3
- PackingGroup
- II
- HS Code
- 29310095 · 29310095
- Storage Class
- 3 · 3 - Flammable liquids
- Hazard Classifications
- 2 Flam · Eye Irrit. 2Flam. Liq. 2Skin Irrit. 2STOT SE 3
- REACH Registrations
- Active
Safety & regulation
GHS classification
GHS Classification
This chemical does not meet GHS hazard criteria for 5.1% (4 of 79) of reports.
Danger
H225 (89.9%): Highly Flammable liquid and vapor [Danger Flammable liquids]
P210, P233, P240, P241, P242, P243, P261, P264, P264+P265, P271, P273, P280, P302+P352, P303+P361+P353, P304+P340, P305+P351+P338, P319, P321, P332+P317, P337+P317, P362+P364, P370+P378, P391, P403+P233, P403+P235, P405, and P501 (click each P-code to see the statement)
Aggregated GHS information provided per 79 reports by companies from 10 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.
Hazard information
Regulatory Information
Chemical: Silane, (chloromethyl)trimethyl-
Status: Active Update: 07-09-2022 https://echa.europa.eu/registration-dossier/-/registered-dossier/16484
(Chloromethyl)trimethylsilane: Does not have an individual approval but may be used under an appropriate group standard
Hazard Classes and CategoriesFlam. Liq. 2 (89.9%)
Safety data
- F
- 10-21
- PPE
- Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter
- wgk
- 3
- tsca
- TSCA listed
- ridadr
- UN 1993 3/PG 2
- hs_code
- 29310095
- risk_code
- 11-36/37/38-34
- Signal word
- Danger
- Symbol(GHS)
- GHS02,GHS07
- hazard_code
- F,Xi,C
- hazard_note
- Irritant/Highly Flammable
- safety_code
- 16-26-36-29-37/39-33
- hazard_class
- 3
- Storage Class
- 3 - Flammable liquids
- packing_group
- II
- target organs
- Respiratory system
- Hazard statements
- H302+H312+H332-H315-H319-H335-H225
- REACH Registrations
- Active
- Hazard Classifications
- Eye Irrit. 2Flam. Liq. 2Skin Irrit. 2STOT SE 3
- Precautionary statements
- P501-P270-P240-P261-P210-P233-P243-P241-P242-P271-P264-P280-P370+P378-P337+P313-P305+P351+P338-P362+P364-P303+P361+P353-P332+P313-P301+P312+P330-P304+P340+P312-P403+P233-P403+P235-P405
Chemistry & industry
Uses & manufacturing
General Manufacturing InformationSilane, (chloromethyl)trimethyl-: ACTIVE
Applications
DescriptionChloromethyltrimethylsilane is a chemical compound belonging to the trifluoroacetic acid group. It is an essential synthetic intermediate in organic chemistry, used to prepare many types of compounds, including pharmaceuticals, agrochemicals, and dyes. The molecule consists of three silanes linked together by methylene bridges. The synthesis of Chloromethyltrimethylsilane involves reacting a mixture of hydrochloric acid and trifluoroacetic acid with methyl ketones in the presence of ethylene diamine and particles.
Uses(Chloromethyl)trimethylsilane is used for Wittig reaction and building blocks.
Uses(Chloromethyl)trimethylsilane can be treated with aldehydes or ketones in the presence of triphenylphosphine to synthesize terminal alkenes. It can also be used in the preparation of a reagent, trimethylsilylmethyl magnesium chloride, commonly used in Peterson methylenation.
Upstream & downstream products
Upstream raw materials
Downstream products
Suppliers100 total
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Related reactions
117 records
Compound notes
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