CAS 2491-06-7 N,N-Dimethylglycine hydrochloride (HCID 75605)

Overview

See also: N,N-Dimethylglycine (has active moiety).

Names & identifiers

Preferred name: N,N-Dimethylglycine hydrochloride
IUPAC: 2-(dimethylamino)acetic acid;hydrochloride
English name: N,N-Dimethylglycine hydrochloride
Molecular formula: C4H10ClNO2
Molecular weight: 139.58

Names & synonyms

N,N-Dimethylglycine hydrochlorideN,N-Dimethylglycine HClYXK75EAE92N,N-Dimethylaminoacetic acid hydrochlorideRefChem:55680219-648-22491-06-7Dimethylglycine hydrochlorideGlycine, N,N-dimethyl-, hydrochlorideMFCD00012610N-Methylsarcosine hydrochlorideGlycine, N,N-dimethyl-, hydrochloride (1:1)

Show more names

DIMETHYLGLYCINE HCLDIMETHYL GLYCINE HYDROCHLORIDEDMG HYDROCHLORIDEH-GLY(2ME)-OH HCLIFLAB-BB F1929-1772N,N-DIMETHYL-GLY-OH HCLN,N-DiMethyl-d3-glycine HCl

(Dimethylamino)acetic acid hydrochloride2-(dimethylamino)acetic acid hydrochloride2-(dimethylamino)acetic acid;hydrochlorideN,N-Dimethylglycinium chlorideCCRIS 3352EINECS 219-648-2UNII-YXK75EAE92AI3-62132

Database identifiers

CAS: 2491-06-7
PubChem CID: 75605
DTXSID: DTXSID1062463
UNII: YXK75EAE92
EC Number: 219-648-2

Properties

Computed structural properties

Topological polar surface area: 40.5 Å²
Hydrogen bond donors: 2
Hydrogen bond acceptors: 3
Rotatable bonds: 2
Heavy atoms: 8
Formal charge: 0
Complexity: 70.1

Physicochemical properties

Melting point: 189 · 189-194 °C(lit.)
Boiling point: 397.74 ℃[at · 397.74℃[at 101 325 Pa]
Density: 1.326 · 1.326[at 20℃]
vapor pressure: 0 Pa · 0Pa at 25℃
storage temp.: 30 °C · Store below +30°C.
solubility: 10 mg/ml; · DMSO: 10 mg/ml; PBS (pH 7.2): 10 mg/ml
form: Crystalline Powder
color: White
Odor: Slight to none
Water Solubility: 100 g/L · 100 g/L (20 ºC)
Sensitive: Hygroscopic
Merck: 14 · 14,3244
BRN: 3910578 · 3910578
InChI: 1S/C4H9NO2.ClH/c1-5(2)3-4(6)7;/h3H2,1-2H3,(H,6,7);1H
InChIKey: FKASAVXZZLJTNX-UHFFFAOYSA-N
SMILES: [Cl-].N(CC(=O)O)(C)C.[H+]
LogP: -0.3 · -0.3
CAS DataBase Reference: 2491 · 2491-06-7(CAS DataBase Reference)
EWG's Food Scores: 1 · 1
FDA UNII: 75 EAE92 · YXK75EAE92
EPA Substance Registry System: Glycine, N,N-dimethyl-, hydrochloride (2491-06-7)
UNSPSC Code: 12352209 · 12352209
NACRES: 26 · NA.26
Symbol(GHS): 7 · GHS07
Signal word: Warning
Hazard statements: 315 · H315-H319-H335
Precautionary statements: 261 · P261-P280a-P304+P340-P305+P351+P338-P405-P501a
Risk Statements: 36 · 36/37/38
Safety Statements: 22 · 22-24/25
WGK Germany: 2 · 2
RTECS: 9995000 · MB9995000
TSCA: TSCA listed
HS Code: 29212900 · 29212900
Storage Class: 11 · 11 - Combustible Solids
REACH Registrations: Inactive

Safety & regulation

GHS classification

GHS Classification · 5 items

This chemical does not meet GHS hazard criteria for 36.4% (4 of 11) of reports.

Warning

H315 (54.5%): Causes skin irritation [Warning Skin corrosion/irritation]

P261, P264, P264+P265, P271, P280, P302+P352, P304+P340, P305+P351+P338, P319, P321, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501 (click each P-code to see the statement)

Aggregated GHS information provided per 11 reports by companies from 4 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

Hazard information

Regulatory Information · 3 items

Chemical: Glycine, N,N-dimethyl-, hydrochloride

Status: Cease Manufacture Update: 22-11-2017 https://echa.europa.eu/registration-dossier/-/registered-dossier/21092

Glycine, N,N-dimethyl-, hydrochloride: Does not have an individual approval but may be used as a component in a product covered by a group standard. It is not approved for use as a chemical in its own right.

Safety data

wgk: 2
tsca: TSCA listed
rtecs: MB9995000
hs_code: 29212900
risk_code: 36/37/38
Signal word: Warning
Symbol(GHS): GHS07
safety_code: 22-24/25
Storage Class: 11 - Combustible Solids
Hazard statements: H315-H319-H335
REACH Registrations: Inactive
Precautionary statements: P261-P280a-P304+P340-P305+P351+P338-P405-P501a

Chemistry & industry

Uses & manufacturing

General Manufacturing InformationGlycine, N,N-dimethyl-, hydrochloride (1:1): INACTIVE

Applications · 1 item

UsesN,N-Dimethylglycine (DMG) is a natural N-methylated glycine that is used in comparative analysis with other N-methylated glycines such as sarcosine and βine. Used in the development of glycine-based ionic liquids and emulsifiers. Also it is potentially useful as a biomarker of protein degradation in COPD patients. DMG is used as a substrate to identify, differentiate and characterize amino acid methyltransferase(s).