Basic information
- CAS
2754-32-7- Standard SMILES
C[Si](C)(O)c1ccc([Si](C)(C)O)cc1- InChIKey
YBNBOGKRCOCJHH-UHFFFAOYSA-N- Molecular formula
- C10H18O2Si2
- Average molar mass
- 226.42 g/mol
- Monoisotopic mass
- 226.08453288
Names & identifiers
- Preferred name
- Silanol, 1,1'-(1,4-phenylene)bis(1,1-dimethyl-
- IUPAC
- hydroxy-[4-[hydroxy(dimethyl)silyl]phenyl]-dimethylsilane
- English name
- 1,4-Bis(hydroxydimethylsilyl)benzene
- Molecular formula
- C10H18O2Si2
- Molecular weight
- 226.42
Names & synonyms
2754-32-7p-Phenylenebis(dimethylsilanol)1,4-Bis(dimethylhydroxysilyl)benzenep-Bis(dimethylhydroxysilyl)benzeneSilanol, 1,4-phenylenebis(dimethyl-Silanol, 1,4-phenylenebis[dimethyl-P-phenylenebis[dimethylsilanol]Silanol, 1,1'-(1,4-phenylene)bis[1,1-dimethyl-Silanol, p-phenylenebis(dimethyl-EINECS 220-405-8NSC 83943Silanol, 1,1'-(1,4-phenylene)bis(1,1-dimethyl-
Show more names
DK012DKFELEX03331,4-phenylenebis[dimethyl-silanoBis(hydroxydimethylsilyl)benzene1,4-Phenylenebis(dimethylsilanol)(1,4-Phenylene)bis(dimethylsilanol)1,4-BIS(HYDROXYDIMETHYLSILYL)BENZENEBenzene-1,4-diylbis(dimethylsilanol)1,4 BIS(DIMETHYLHYDROXYSILYL)BENZENE
DTXSID1062625Silanol, p-phenylenebis[dimethyl-1,1'-(1,4-Phenylene)bis[1,1-dimethylsilanol]1,1'-(1,4-Phenylene)bis(1,1-dimethylsilanol)RefChem:885384DTXCID1037690Silanol, p-phenylenebis(dimethyl-(8CI)220-405-8
Properties
Computed structural properties
- Topological polar surface area
- 40.5 Ų
- Hydrogen bond donors
- 2
- Hydrogen bond acceptors
- 2
- Rotatable bonds
- 2
- Heavy atoms
- 14
- Formal charge
- 0
- Complexity
- 174
Physicochemical properties
- Melting point
- 133 · 133-136 °C(lit.)
- Boiling point
- 289.6 · 289.6±36.0 °C(Predicted)
- Density
- 1.02 · 1.02±0.1 g/cm3(Predicted)
- Flash point
- 110 °C · >110°C
- storage temp.
- 2 · 2-8°C
- pka
- 13.91 · 13.91±0.53(Predicted)
- Appearance
- White to off-white Solid
- Hydrolytic Sensitivity
- 4 · 4: no reaction with water under neutral conditions
- InChI
- InChI=1S/C10H18O2Si2/c1-13(2,11)9-5-7-10(8-6-9)14(3,4)12/h5-8,11-12H,1-4H3
- InChIKey
- YBNBOGKRCOCJHH-UHFFFAOYSA-N
- SMILES
- C1([Si](C)(C)O)=CC=C([Si](C)(C)O)C=C1
- CAS DataBase Reference
- 2754 · 2754-32-7(CAS DataBase Reference)
- FDA UNII
- 2 H886KS3J3 · 2H886KS3J3
- EPA Substance Registry System
- 1 · Silanol, 1,4-phenylenebis[dimethyl- (2754-32-7)
- Symbol(GHS)
- 7 · GHS07
Safety & regulation
Safety information is for reference only and does not replace the supplier’s Safety Data Sheet (SDS), applicable regulations, or professional assessment.
GHS classification
GHS Classification
Warning
H302 (50%): Harmful if swallowed [Warning Acute toxicity, oral]
P261, P264, P264+P265, P270, P271, P280, P301+P317, P302+P352, P304+P340, P305+P351+P338, P317, P319, P321, P330, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501 (click each P-code to see the statement)
Aggregated GHS information provided per 2 reports by companies from 2 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.
Hazard information
Hazard Classes and CategoriesAcute Tox. 4 (50%)
Safety data
- wgk
- 3
- tsca
- TSCA listed
- hs_code
- 2931900090
- risk_code
- 36/37/38
- Signal word
- Warning
- Symbol(GHS)
- GHS07
- safety_code
- 26-36/37/39
- Hazard statements
- H319
- Precautionary statements
- P305+P351+P338
Chemistry & industry
Uses & manufacturing
General Manufacturing InformationSilanol, 1,1'-(1,4-phenylene)bis[1,1-dimethyl-: ACTIVE
Applications
Uses1,4-Bis(hydroxydimethylsilyl)benzene is an effective silicon nucleophile for catalyzed palladium cross-coupling reactions.
Preparation methods
PreparationUsing p-dibromobenzene, dimethyldimethoxysilane, and magnesium shavings as raw materials, the phenylenesiloxysilane monomer 1,4-bis(dimethylmethoxysilyl)benzene was synthesized via the Grignard method. The target product, 1,4-Bis(hydroxydimethylsilyl)benzene, was then obtained via hydrolysis.
Suppliers78 total
阿诺西（上海）生物技术有限公司400-1107768 15058188853 · [email protected]
郑州阿尔法化工有限公司+86-18530059196 · [email protected]
Hebei Chuanghai Biotechnology Co., Ltd+86-17732866630 · [email protected]
毕佳索（上海毕得医药科技股份有限公司）400-6005915 · [email protected]
上海麦克林生化科技股份有限公司021-50706066 15221275939 · [email protected]
温州共赢化学有限公司+86-0086-577-64498589 +86-15355981851 · [email protected]
上海毕得医药科技股份有限公司400-1647117 13681763483 · [email protected]
Related reactions
1 records
Compound notes
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