m-Aminoacetanilide

HCID 7604CAS 102-28-3

Basic information

Standard SMILES
CC(=O)Nc1cccc(N)c1
InChIKey
PEMGGJDINLGTON-UHFFFAOYSA-N
Molecular formula
C8H10N2O
Average molar mass
150.18 g/mol
Monoisotopic mass
150.07931294

Overview

M-aminoacetanilide is a gray solid. (NTP, 1992)

Names & identifiers

Preferred name
m-Aminoacetanilide
IUPAC
N-(3-aminophenyl)acetamide
English name
N1-(3-Aminophenyl)acetamide
Molecular formula
C8H10N2O
Molecular weight
150.18

Names & synonyms

N-(3-Aminophenyl)acetamide102-28-33'-AminoacetanilideM-AMINOACETANILIDE3-AcetamidoanilineAcetamide, N-(3-aminophenyl)-M-Acetaminoanilinem-(Acetylamino)anilineN-Acetyl-m-phenylenediamine3-Amino-N-acetylaniline3-Aminoacetanilid3-Acetylaminoaniline
Show more names
META AMINO ACETANILIDE3-AMINOACETANILIDEFR-2203AKOS BB-8162WLN: ZR CMV13-AcetamidoaniLASISCHEM B52481
Acetanilide, 3'-amino-1-Amino-3-(acetylamino)benzene3-Aminoacetanilid [Czech]3-(Acetylamino)anilinem-AcetamidoanilineN-Acetyl-m-fenylendiaminCCRIS 4574NSC 165576

Database identifiers

CAS
102-28-3
PubChem CID
7604
DTXSID
DTXSID2024454
ChEMBL
CHEMBL1606123
UNII
Q5K7HYS7JJ
EC Number
203-021-5
Nikkaji
J43.351I

Properties

Computed structural properties

XLogP
0.9
Topological polar surface area
55.1 Ų
Hydrogen bond donors
2
Hydrogen bond acceptors
2
Rotatable bonds
1
Heavy atoms
11

Experimental & physicochemical properties

Chemical ClassesNitrogen Compounds -> Other Aromatics (Nitrogen)
SpringerMaterials Properties13C nuclear magnetic resonance spectrum
Solubility10 to 50 mg/mL at 75 °F (NTP, 1992)
Boiling PointDecomposes at 1449 °F (NTP, 1992)
Melting Point187.7 to 189.5 °F (NTP, 1992)
Physical Description · 2 items

M-aminoacetanilide is a gray solid. (NTP, 1992)

Gray solid; [CAMEO] Light brown crystalline powder; [Acros Organics MSDS]

Physicochemical properties

Melting point
86 · 86-88 °C(lit.)
Boiling point
271.72 °C · 271.72°C (rough estimate)
Density
1.1392 · 1.1392 (rough estimate)
refractive index
1.618 · 1.6180 (estimate)
storage temp.
Keep in dark place,Inert atmosphere,Room temperature
form
powder to crystal

Safety & regulation

GHS classification

GHS Classification · 4 items

Warning

H302 (21.1%): Harmful if swallowed [Warning Acute toxicity, oral]

P261, P264, P264+P265, P270, P271, P280, P301+P317, P302+P352, P304+P340, P305+P351+P338, P319, P321, P330, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501 (click each P-code to see the statement)

Aggregated GHS information provided per 57 reports by companies from 8 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

Hazard information

Regulatory InformationStatus: Active Update: 30-05-2016 https://echa.europa.eu/registration-dossier/-/registered-dossier/17428
Fire HazardsFlash point data concerning this compound are not available, however, it is probably combustible. (NTP, 1992)
Health HazardsACUTE/CHRONIC HAZARDS: When heated to decomposition this compound emits toxic fumes. (NTP, 1992)
Hazards SummaryA mild eye irritant; [RTECS] An irritant; [Acros Organics MSDS] See Acetanilide.
Reactive GroupAmides and Imides
Reactivity Profile · 1 item

Aromatic amines are chemical bases. They neutralize acids to form salts plus water. These acid-base reactions are exothermic. The amount of heat that is evolved per mole of amine in a neutralization is largely independent of the strength of the amine as a base. Amines may be incompatible with isocyanates, halogenated organics, peroxides, phenols (acidic), epoxides, anhydrides, and acid halides. Flammable gaseous hydrogen is generated by amines in combination with strong reducing agents, such as hydrides.

Safety & protection

Fire FightingFires involving this compound can be controlled using a dry chemical, carbon dioxide or Halon extinguisher. (NTP, 1992)
First Aid · 1 item

EYES: First check the victim for contact lenses and remove if present. Flush victim's eyes with water or normal saline solution for 20 to 30 minutes while simultaneously calling a hospital or poison control center. Do not put any ointments, oils, or medication in the victim's eyes without specific instructions from a physician. IMMEDIATELY transport the victim after flushing eyes to a hospital even if no symptoms (such as redness or irritation) develop.

Nonfire Spill Response · 1 item

SMALL SPILLS AND LEAKAGE: If you spill this chemical, you should dampen the solid spill material with water, then transfer the dampened material to a suitable container. Use absorbent paper dampened with water to pick up any remaining material. Seal your contaminated clothing and the absorbent paper in a vapor-tight plastic bag for eventual disposal. Wash all contaminated surfaces with a soap and water solution. Do not reenter the contaminated area until the Safety Officer (or other responsible person) has verified that the area has been properly cleaned.

Personal Protective Equipment (PPE) · 1 item

RECOMMENDED RESPIRATOR: Where the neat test chemical is weighed and diluted, wear a NIOSH-approved half face respirator equipped with an organic vapor/acid gas cartridge (specific for organic vapors, HCl, acid gas and SO2) with a dust/mist filter. (NTP, 1992)

Safety data

PPE
dust mask type N95 (US), Eyeshields, Gloves
wgk
3
tsca
TSCA listed
rtecs
AD8050000
hs_code
29214200
Toxicity
mouse,LD50,intravenous,320mg/kg (320mg/kg),U.S. Army Armament Research & Development Command, Chemical Systems Laboratory, NIOSH Exchange Chemicals. Vol. NX#02899,

Chemistry & industry

Uses & manufacturing

UsesUsed in organic synthesis; [NTP]
General Manufacturing InformationAcetamide, N-(3-aminophenyl)-: ACTIVE

Applications

Uses3'-Aminoacetanilide is mainly used as reaction intermediates dyes and disperse dyes.

General DescriptionGray solid.

Suppliers50 total

梯希爱(上海)化成工业发展有限公司021-67121386 · [email protected]
上海阿拉丁生化科技股份有限公司400-6206333 13167063860 · [email protected]
杭州景优化工有限公司87211835 13957193240 · [email protected]
河北创海生物科技有限公司+86-86-13131129325 · [email protected]
爱斯特(成都)生物制药股份有限公司+86-28-85122536 85324413 · [email protected]

Related reactions

105 records

Linked notes

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