Janus Green B
Basic information
- CAS
2869-83-2- Standard SMILES
CCN(CC)c1ccc2nc3ccc(N=Nc4ccc(N(C)C)cc4)cc3[n+](-c3ccccc3)c2c1.[Cl-]- InChIKey
XXACTDWGHQXLGW-UHFFFAOYSA-M- Molecular formula
- C30H31N6.Cl
- Average molar mass
- 511.1 g/mol
- Monoisotopic mass
- 510.2298727
Overview
Janus Green B chloride is an organic chloride salt. It has a role as a dye. It contains a Janus Green B cation.
Names & identifiers
- Preferred name
- Janus Green B
- IUPAC
- 8-[[4-(dimethylamino)phenyl]diazenyl]-N,N-diethyl-10-phenylphenazin-10-ium-2-amine chloride
- English name
- Janus Green B
- Molecular formula
- C30H31ClN6
- Molecular weight
- 511.07
Names & synonyms
Janus green B2869-83-2Janus Green VC.I. 11050B9KQ101KHXNSC-139863-(Diethylamino)-7-((4-(dimethylamino)phenyl)azo)-5-phenylphenazinium chlorideDTXSID80883898RefChem:150349DTXCID201023380220-695-6Diazin Green S
Show more names
JGBJanuCI 11050NSC13986KJEL-SORBNSC 13986JANUS GREENCI NO 11050OPTIBOR(TM)
Union Green BMFCD00011758C30H31ClN6Janus Green B chlorideJanus Green B Certified3-(Diethylamino)-7-((p-(dimethylamino)phenyl)azo)-5-phenylphenazinium chloridePhenazinium, 3-(diethylamino)-7-[2-[4-(dimethylamino)phenyl]diazenyl]-5-phenyl-, chloride (1:1)JanusGreenB
Database identifiers
- CAS
2869-83-2- PubChem CID
- 76123
- DTXSID
DTXSID80883898- ChEBI
CHEBI:21184- UNII
- B9KQ101KHX
Properties
Computed structural properties
- Topological polar surface area
- 48 Ų
- Hydrogen bond donors
- 0
- Hydrogen bond acceptors
- 6
- Rotatable bonds
- 7
- Heavy atoms
- 37
- Formal charge
- 0
- Complexity
- 694
Physicochemical properties
- Melting point
- 160 °C · 160 °C (dec.)(lit.)
- vapor pressure
- 2.6 mm · 2.6 mm Hg ( 20 °C)
- storage temp.
- 2 · 2-8°C
- solubility
- 2 O: · H2O: 1 M hot, clear, colorless
- Colour Index
- 11050 · 11050
- form
- Powder
- color
- 10 · ≤10(APHA)
- Water Solubility
- Soluble in water (20 mg/ml at 20°C), ethanol, and slightly soluble in alcohol.
- λmax
- 660 nm, · 660nm, 395nm
- ε(extinction coefficient)
- 28000 at · ≥28000 at 651-677nm in ethanol: water (1:1) at 0.01g/L
- Merck
- 14 · 14,5255
- Stability
- Stable. Incompatible with strong oxidizing agents.
- Biological Applications
- Antimalarialagents; diagnosis of diseases related to amyloid accumulation; diagnostic assays; detecting fungi; nucleic acids; sugars
- Major Application
- diagnostic assay manufacturinghematologyhistology
Safety & regulation
Safety information is for reference only and does not replace the supplier’s Safety Data Sheet (SDS), applicable regulations, or professional assessment.
GHS classification
GHS ClassificationNot Classified
Hazard information
Regulatory Information
Chemical: Phenazinium, 3-(diethylamino)-7-[[4-(dimethylamino)phenyl]azo]-5-phenyl-, chloride
Janus green: Does not have an individual approval but may be used under an appropriate group standard
Hazard Classes and CategoriesNot Classified
Safety data
- PPE
- Eyeshields, Gloves, type N95 (US)
- wgk
- 3
- tsca
- TSCA listed
- rtecs
- SG1633000
- hs_code
- 32041900
- risk_code
- 60-40
- Signal word
- Warning
- Symbol(GHS)
- GHS07
- hazard_code
- T,Xn
- safety_code
- 22-24/25-36
- Storage Class
- 11 - Combustible Solids
- Hazard statements
- H302-H315-H319-H335
- Precautionary statements
- P261-P305+P351+P338
Chemistry & industry
Uses & manufacturing
Household ProductsInformation on 2 consumer products that contain C.I. 11050 in the following categories is provided:
General Manufacturing InformationPhenazinium, 3-(diethylamino)-7-[2-[4-(dimethylamino)phenyl]diazenyl]-5-phenyl-, chloride (1:1): ACTIVE
Applications
UsesJanus Green B is a stain that interacts with DNA and has been used for histology studies including mitochondrial staining, in which its oxidation and reduction reveals alterations to the electron transfer chain. The stain has been utilized in studies for effective and rapid staining of insect chordotonal organs and peripheral nerves, where the nerves appear dark blue in comparison to non stained tissue. With the use of Janus Green B, rabbit lymphatic vessel studies demonstrate that threadlike structures within the lymphatic vessels, known as Bonghan ducts, contain a high density of mitochondria in their cells.
UsesAs dye for cotton, wool; as biological stain; in electrodeposition of copper, Brown, Fellows, US 2882209 (1959 to Udylite Res. Corp.).
Upstream & downstream products
Upstream raw materials
Additional notes
DefinitionChEBI: Janus Green B chloride is an organic chloride salt. It has a role as a dye. It contains a Janus Green B cation.
Related reactions
0 records
No reaction records under the current filter.
Compound notes
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