HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Aminoindane
2-AI · 2-AMINOINDAN · 2-AMINOINDANE · PV-9 · Su-8629 · 2-INDANAMINE · AKOS BC-0645 · INDAN-2-AMINE
Identifiers & Physical Properties
| CAS No. | 2975-41-9 |
|---|---|
| Molecular formula | C9H11N |
| Average molar mass | 133.19 g/mol |
| Monoisotopic mass | 133.08914935 g/mol |
| SMILES | NC1Cc2ccccc2C1 |
| InChIKey | LMHHFZAXSANGGM-UHFFFAOYSA-N |
| PubChem CID | 76310 |
| ChEMBL | CHEMBL1188176 |
| EC No. | 221-021-3 |
| DTXSID | DTXSID40183902 |
Chemical & Physical Properties
| XLogP | 1.7 |
|---|---|
| Topological polar surface area | 26 |
| Hydrogen bond donors | 1 |
| Hydrogen bond acceptors | 1 |
| Rotatable bonds | 0 |
| Heavy atoms | 10 |
| Formal charge | 0 |
| Complexity | 108 |
| Drugs | DEA NFLIS-Drug Category -> Phenethylamines (Aminoindanes) (H)Pharmaceuticals -> Synthetic Cannabinoids or Psychoactive Compounds |
| Melting point | 33-34 °C |
| Boiling point | 103-105 |
| Density | 1.024 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.561(lit.) |
| Flash point | 212 °F |
| pKa (acidity coefficient) | 9.21±0.20(Predicted) |
| Solubility | Slightly soluble in water. |
| CAS DataBase Reference | 2975-41-9(CAS DataBase Reference) |
| FDA UNII | 1P810SQ3EY |
| NIST Chemistry Reference | 1h-Inden-2-amine, 2,3-dihydro-(2975-41-9) |
| GHS pictogram | GHS05,GHS06 |
| Signal word | Warning |
| GHS hazard statements | H301-H314-H318 |
| GHS precautionary statements | P280-P305+P351+P338-P309-P310 |
| Hazard symbols | Xi,C,Xn |
| Risk statements (R) | 36/37/38-20/21/22 |
| Safety statements (S) | 26-36 |
| UN transport number | UN 2735 8/PG III |
| Water hazard class (WGK) | 3 |
| Hazard Note | Corrosive |
| Hazard class | IRRITANT |
| Packing group | III |
| Limited quantities | 5.0 L (1.3 gallons) (liquid) or 5.0 kg (11 lbs) (solid) |
| Excepted quantities | Max Inner Pack (30g or 30ml) and Max Outer Pack (1Kg or 1L) |
Safety & Regulations
| GHS classification | WarningH315 (91.2%): Causes skin irritation [Warning Skin corrosion/irritation]P261, P264, P264+P265, P271, P280, P302+P352, P304+P340, P305+P351+P338, P319, P321, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501 (click each P-code to see the statement)Aggregated GHS information provided per 57 reports by companies from 6 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies. |
|---|---|
| Hazard Classes and Categories | Skin Irrit. 2 (91.2%) |
| Water hazard class (WGK) | 3 |
| UN transport number | UN 2735 8/PG III |
| Risk statements (R) | 36/37/38-20/21/22 |
| Signal word | Warning |
| GHS pictogram | GHS05,GHS06 |
| Hazard symbols | Xi,C,Xn |
| hazard_note | Corrosive |
| Safety statements (S) | 26-36 |
| Hazard class | 8 |
| Packing group | III |
| GHS hazard statements | H301-H314-H318 |
| Limited quantities | 5.0 L (1.3 gallons) (liquid) or 5.0 kg (11 lbs) (solid) |
| Excepted quantities | Max Inner Pack (30g or 30ml) and Max Outer Pack (1Kg or 1L) |
| GHS precautionary statements | P280-P305+P351+P338-P309-P310 |
Applications & Uses
Uses
2-Aminoindan is an analgesic with sympathomimetic activity. 2-Aminoindan is an inhibitor norepinephrine methyltransferase.
Uses
2-Aminoindan is an analgesic with sympathomimetic activity, It is an inhibitor norepinephrine methyltransferase.
General Description
2-Aminoindan (2-Aminoindane) is an analog of amphetamine. It shows a potential bronchodilator and analgesic effect. The impact of the intramolecular N-H···Π hydrogen bonding on the conformations of 2-Al has been analyzed.