Basic information
- CAS
3055-94-5- Standard SMILES
CCCCCCCCCCCCOCCOCCOCCO- InChIKey
FKMHSNTVILORFA-UHFFFAOYSA-N- Molecular formula
- C18H38O4
- Average molar mass
- 318.5 g/mol
- Monoisotopic mass
- 318.2770097
Overview
The CIR Expert Panel concluded that the alkyl PEG ethers, listed below, are safe in the present practices of use and concentration described in this safety assessment when formulated to be nonirritating. This assessment is also intended to address future alkyl PEG ether cosmetic ingredients that vary from those ingredients recited herein only by the number of ethylene glycol repeat units...Laureth-3...
Names & identifiers
- Preferred name
- 2-(2-(2-(Dodecyloxy)ethoxy)ethoxy)ethanol
- IUPAC
- 2-[2-(2-dodecoxyethoxy)ethoxy]ethanol
- English name
- Triethylene glycol mono-n-dodecyl ether
- Molecular formula
- C18H38O4
- Molecular weight
- 318.49
Names & synonyms
3055-94-5Triethylene glycol monododecyl etherLauryltriglycol etherLaureth-3Lauryl alcohol triglycol etherDodecyl triethylene glycol etherEthanol, 2-[2-[2-(dodecyloxy)ethoxy]ethoxy]-2-(2-(2-(Dodecyloxy)ethoxy)ethoxy)ethanolEINECS 221-280-2F32E4CB0UJLauryl alcohol di(oxyethylene) ethanolEthanol, 2-(2-(2-(dodecyloxy)ethoxy)ethoxy)-
Show more names
C12E3DODECYLTRIGLYCOL3-Dodecylalcoholn-dodecyl-PEG3-OHDodecyloxy-PEG3-OHlauryltriethoxylateDODECYLTRIETHOXYLATElauryltriglycolether
BRN 1779029Triethylene glycol lauryl etherC12EOx2-[2-[2-(dodecyloxy)ethoxy]ethoxy]ethanolDTXSID6058631RefChem:452564LAURETH-3 [INCI]DTXCID0032318
Database identifiers
- CAS
3055-94-5
Properties
Computed structural properties
- XLogP
- 4.8
- Topological polar surface area
- 47.9 Ų
- Hydrogen bond donors
- 1
- Hydrogen bond acceptors
- 4
- Rotatable bonds
- 19
- Heavy atoms
- 22
- Formal charge
- 0
- Complexity
- 188
Experimental & physicochemical properties
Cosmetics
Cosmetic ingredients (Laureth-3) -> CIR (Cosmetic Ingredient Review)
Surfactant; Emulsifying
Surfactants
Surfactant -> linear alkylbenzyl sulfonate (LAS)
Surfactant
Physicochemical properties
- Melting point
- 16.5 · 16.5-17.0 °C
- Boiling point
- 153 °C · 153 °C(Press: 0.035 Torr)
- Density
- 0.93 · 0.93
- refractive index
- 20 · n20/D 1.451
- Flash point
- 16 °C · 16 °C
- storage temp.
- 2 · 2-8°C
- solubility
- Chloroform (Slightly), Ethyl Acetate (Slightly), Methanol (Slightly)
- pka
- 14.36 · 14.36±0.10(Predicted)
- form
- powder to lump to clear liquid
- color
- White or Colorless to Almost white or Almost colorless
Safety & regulation
Safety information is for reference only and does not replace the supplier’s Safety Data Sheet (SDS), applicable regulations, or professional assessment.
GHS classification
GHS Classification
Danger
H318 (48.8%): Causes serious eye damage [Danger Serious eye damage/eye irritation]
P264+P265, P273, P280, P305+P351+P338, P305+P354+P338, P317, P337+P317, P391, and P501 (click each P-code to see the statement)
Aggregated GHS information provided per 80 reports by companies from 4 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.
Danger
H302: Harmful if swallowed [Warning Acute toxicity, oral]
Hazard information
Regulatory Information
Chemical: Ethanol, 2-[2-[2-(dodecyloxy)ethoxy]ethoxy]-
Ethanol, 2-[2-[2-(dodecyloxy)ethoxy]ethoxy]-: Does not have an individual approval but may be used as a component in a product covered by a group standard. It is not approved for use as a chemical in its own right.
Other Safety InformationIMAP assessments - Ethoxylates of aliphatic alcohols (>C6): Human health tier II assessment
EPA Safer ChemicalChemical: Dodecyl triethylene glycol ether
Hazard Classes and Categories
Eye Dam. 1 (48.8%)
Acute toxicity (ingestion) - category 4
Toxicology
Toxicity Summary
The CIR Expert Panel concluded that the alkyl PEG ethers, listed below, are safe in the present practices of use and concentration described in this safety assessment when formulated to be nonirritating. This assessment is also intended to address future alkyl PEG ether cosmetic ingredients that vary from those ingredients recited herein only by the number of ethylene glycol repeat units...Laureth-3...
Chemistry & industry
Uses & manufacturing
UsesCIR ingredient: Laureth-3
Household ProductsInformation on 36 consumer products that contain Laureth-3 in the following categories is provided:
Use Classification
EPA Safer Chemical Functional Use Classes -> Surfactants
Safer Chemical Classes -> Green circle - The chemical has been verified to be of low concern
Cosmetics -> Surfactant; Emulsifying
General Manufacturing InformationEthanol, 2-[2-[2-(dodecyloxy)ethoxy]ethoxy]-: ACTIVE
Applications
UsesTriethyleneglycol Monolauryl Ether is used as a reagent in the synthesis of N,N-dimethyl-N-dodecyl polyoxyethylene amine-based surfactants. It is also used as a reagent in the synthesis of hybrid carbohydrate/oligoethylene oxide surfactants.
UsesTriethyleneglycol monododecyl ether is a surfactant, detergent, and emulsifier used in cosmetic preparations.
Upstream & downstream products
Upstream raw materials
Related reactions
0 records
No reaction records under the current filter.
Compound notes
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