Laureth-12
Basic information
- CAS
3056-00-6- Standard SMILES
CCCCCCCCCCCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCO- InChIKey
WMPGRAUYWYBJKX-UHFFFAOYSA-N- Molecular formula
- C36H74O13
- Average molar mass
- 715 g/mol
- Monoisotopic mass
- 714.51294241
Overview
The CIR Expert Panel concluded that the alkyl PEG ethers, listed below, are safe in the present practices of use and concentration described in this safety assessment when formulated to be nonirritating. This assessment is also intended to address future alkyl PEG ether cosmetic ingredients that vary from those ingredients recited herein only by the number of ethylene glycol repeat units...Laureth-12...
Names & identifiers
- Preferred name
- Laureth-12
- IUPAC
- 2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-(2-dodecoxyethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethanol
- English name
- 3,6,9,12,15,18,21,24,27,30,33,36-dodecaoxaoctatetracontan-1-ol
- Molecular formula
- C36H74O13
- Molecular weight
- 714.97
Names & synonyms
Laureth-12PEG-12 Lauryl etherEINECS 221-286-5DTXSID50184647RefChem:7669LIPOCOL L-12DTXCID90107138DODECAETHYLENE MONODODECYL ETHERDODECAETHYLENEGLYCOL DODECYL ETHERETHANOL, 2-(2-(2-(2-(2-(2-(2-(2-(2-(2-(2-(2-(DODECYLOXY)ETHOXY)ETHOXY)ETHOXY)ETHOXY)ETHOXY)ETHOXY)ETHOXY)ETHOXY)ETHOXY)ETHOXY)ETHOXY)-OAH19558U13,6,9,12,15,18,21,24,27,30,33,36-Dodecaoxaoctatetracontan-1-ol
Show more names
n-dodecyl-PEG12-OHDodecyl dodeca(oxyethylene) etherPolidocanol Impurity 4 (Polidocanol E12)35-(Dodecyloxy)-3,6,9,12,15,18,21,24,27,30,33-undecaoxapentatriacontane-1-ol(3,6,9,12,15,18,21,24,27,30,33,36-Dodecaoxahexatriacontane-1-yl)dodecyl ether
3056-00-62-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-(2-dodecoxyethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethanolPolidocanol Impurity 5SCHEMBL8820699WMPGRAUYWYBJKX-UHFFFAOYSA-Ndodeca-ethylene glycol monododecyl etherPolidocanol Impurity 3 (Polidocanol E12)NS00013824
Properties
Computed structural properties
- XLogP
- 3.5
- Topological polar surface area
- 131 Ų
- Hydrogen bond donors
- 1
- Hydrogen bond acceptors
- 13
- Rotatable bonds
- 46
- Heavy atoms
- 49
- Formal charge
- 0
- Complexity
- 563
Experimental & physicochemical properties
Cosmetics
Cosmetic ingredients (Laureth-12) -> CIR (Cosmetic Ingredient Review)
Emulsifying; Surfactant
Physicochemical properties
- Boiling point
- 700.8 · 700.8±55.0 °C(Predicted)
- Density
- 1.026 · 1.026±0.06 g/cm3(Predicted)
- pka
- 14.36 · 14.36±0.10(Predicted)
- Odor
- 100 % · at 100.00%. bland
- Cosmetics Ingredients Functions
- SURFACTANT - CLEANSINGSURFACTANT - EMULSIFYING
- LogP
- 2.324 · 2.324 (est)
- FDA UNII
- 19558 U1 · OAH19558U1
- Symbol(GHS)
- 7 · GHS07,GHS05
- Signal word
- Danger
- Hazard statements
- 302 · H302-H318
- Precautionary statements
- 264 · P264-P270-P301+P312-P330-P501-P280-P305+P351+P338-P310
Safety & regulation
Safety information is for reference only and does not replace the supplier’s Safety Data Sheet (SDS), applicable regulations, or professional assessment.
GHS classification
GHS Classification
Danger
H302 (100%): Harmful if swallowed [Warning Acute toxicity, oral]
P264, P264+P265, P270, P280, P301+P317, P305+P354+P338, P317, P330, and P501 (click each P-code to see the statement)
The GHS information provided by 1 company from 1 notification to the ECHA C&L Inventory.
Hazard information
Regulatory Information3,6,9,12,15,18,21,24,27,30,33,36-Dodecaoxaoctatetracontan-1-ol: Does not have an individual approval but may be used as a component in a product covered by a group standard. It is not approved for use as a chemical in its own right.
Hazard Classes and CategoriesAcute Tox. 4 (100%)
Toxicology
Toxicity Summary
The CIR Expert Panel concluded that the alkyl PEG ethers, listed below, are safe in the present practices of use and concentration described in this safety assessment when formulated to be nonirritating. This assessment is also intended to address future alkyl PEG ether cosmetic ingredients that vary from those ingredients recited herein only by the number of ethylene glycol repeat units...Laureth-12...
Safe for use in cosmetics, with qualifications
Safety data
- Signal word
- Danger
- Symbol(GHS)
- GHS07,GHS05
- Hazard statements
- H302-H318
- Precautionary statements
- P264-P270-P301+P312-P330-P501-P280-P305+P351+P338-P310
Chemistry & industry
Uses & manufacturing
UsesCIR ingredient: Laureth-12
Household ProductsInformation on 24 consumer products that contain Laureth-12 in the following categories is provided:
Use ClassificationCosmetics -> Emulsifying; Surfactant
Related reactions
0 records
No reaction records under the current filter.
Compound notes
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