Basic information
- CAS
3077-12-1- Standard SMILES
Cc1ccc(N(CCO)CCO)cc1- InChIKey
JUVSRZCUMWZBFK-UHFFFAOYSA-N- Molecular formula
- C11H17NO2
- Average molar mass
- 195.26 g/mol
- Monoisotopic mass
- 195.12592879
Overview
lysosome stabilizing agent
Names & identifiers
- Preferred name
- N,N-Bis(2-hydroxyethyl)-p-toluidine
- IUPAC
- 2-[N-(2-hydroxyethyl)-4-methylanilino]ethanol
- English name
- 2,2'-(P-TOLYLIMINO)DIETHANOL
- Molecular formula
- C11H17NO2
- Molecular weight
- 195.26
Names & synonyms
3077-12-1N,N-Bis(2-hydroxyethyl)-p-toluidineN,N-Bis(2-hydroxyethyl)-4-toluidineEthanol, 2,2'-[(4-methylphenyl)imino]bis-R00STP10PRDHEPT cpdN,N-Dihydroxyethyl-p-toluidineNSC-103354Ethanol, 2,2'-((4-methylphenyl)imino)bis-RefChem:822141221-359-12,2'-(p-Tolylazanediyl)diethanol
Show more names
DHETN,N-DIHYDROXYETHYL-P-TOLUIDINE(DHPT)2,2'-(P-TOLYLIMINO)D-(P-TOLYLIMINO)DIETHANOLN-(P-TOLYL)DIETHANOLAMINEN,N-dioxyethyl-p-toluidine
2,2'-(p-Tolylimino)diethanolp-TolyldiethanolamineDiethylol-p-toluidineN,N-Diethanol-p-toluidine2,2'-[(4-methylphenyl)imino]diethanolN-(4-Methylphenyl)diethanolamine2,2'-(4-Methylphenylimino)diethanolN,N-Di(2-hydroxyethyl)-para-toluidine
Database identifiers
- CAS
3077-12-1- PubChem CID
- 76497
- DTXSID
DTXSID0044650
Properties
Computed structural properties
- XLogP
- 1
- Topological polar surface area
- 43.7 Ų
- Hydrogen bond donors
- 2
- Hydrogen bond acceptors
- 3
- Rotatable bonds
- 5
- Heavy atoms
- 14
- Formal charge
- 0
- Complexity
- 138
Experimental & physicochemical properties
Chemical ClassesNitrogen Compounds -> Other Aromatics (Nitrogen)
LogP1.09
Vapor Pressure0.00000073 [mmHg]
Physical DescriptionWhite powder with a slight odor; [3M MSDS]
Collision Cross Section141.8 Ų [M+H]+ [CCS Type: DT; Buffer gas: N2; Ionization: APCI+; Dataset: TOXCAST; Source Identifier: DTXSID0044650]
Physicochemical properties
- Melting point
- 49 · 49-53 °C (lit.)
- Boiling point
- 338 · 338-340 °C (lit.)
- Density
- 1.0654 · 1.0654 (rough estimate)
- vapor pressure
- 0 Pa · 0Pa at 25℃
- refractive index
- 1.533 · 1.5330 (estimate)
- Flash point
- 230 °F · >230 °F
- storage temp.
Safety & regulation
Safety information is for reference only and does not replace the supplier’s Safety Data Sheet (SDS), applicable regulations, or professional assessment.
GHS classification
GHS Classification
This chemical does not meet GHS hazard criteria for 5.6% (21 of 372) of reports.
Danger
H302 (88.2%): Harmful if swallowed [Warning Acute toxicity, oral]
P261, P264, P264+P265, P270, P271, P272, P273, P280, P301+P317, P302+P352, P304+P340, P305+P351+P338, P305+P354+P338, P317, P319, P321, P330, P332+P317, P333+P317, P337+P317, P362+P364, P403+P233, P405, and P501 (click each P-code to see the statement)
Aggregated GHS information provided per 372 reports by companies from 11 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.
Hazard information
Regulatory Information
Chemical: Ethanol, 2,2'-[(4-methylphenyl)imino]bis-
REACH registered substance: 2,2'-[(4-methylphenyl)imino]bisethanol (EC: 221-359-1)
Ethanol, 2,2'-[(4-methylphenyl)imino]bis-: Does not have an individual approval but may be used under an appropriate group standard
Hazards SummaryCauses flaccid paralysis without anesthesia (usually neuromuscular blockage), ataxia, and respiratory depression in oral lethal-dose studies of rodents; [RTECS] A moderate eye irritant; May induce methemoglobinemia; [3M MSDS] See Toluidine.
Hazard Classes and CategoriesAcute Tox. 4 (88.2%)
Toxicology
Adverse EffectsNeurotoxin - Other CNS neurotoxin
Safety data
- F
- 1-10
Chemistry & industry
Uses & manufacturing
UsesLysosome stabilizing agent. [ChemIDplus] Used as an accelerator and intermediate; [3M MSDS]
General Manufacturing InformationEthanol, 2,2'-[(4-methylphenyl)imino]bis-: ACTIVE
Applications
UsesEmulsifier, dyestuff intermediate.
Uses2,2′-(4-Methylphenylimino)diethanol (p-tolyl diethanolamine) was used as an activating amine.
Suppliers101 total
国药集团化学试剂有限公司86-21-63210123 · [email protected]
梯希爱(上海)化成工业发展有限公司021-67121386 · [email protected]
上海阿拉丁生化科技股份有限公司400-6206333 13167063860 · [email protected]
Changzhou Carman Chemical Co., Ltd.15061933924
河北创海生物科技有限公司+86-86-13131129325 · [email protected]
爱斯特（成都）生物制药股份有限公司+86-28-85122536 85324413 · [email protected]
Dayang Chem (Hangzhou) Co.,Ltd.+86-0571-88938639 17705817739 · [email protected]
科瑞迪化学400-821-5857 021-64326257 · [email protected]
Syntechem Co.,Ltd
Related reactions
2 records
Compound notes
Loading…