Basic information
- CAS
3184-13-2- Standard SMILES
Cl.NCCC[C@H](N)C(=O)O- InChIKey
GGTYBZJRPHEQDG-WCCKRBBISA-N- Molecular formula
- C5H12N2O2.ClH
- Average molar mass
- 168.62 g/mol
- Monoisotopic mass
- 168.06655534
Overview
L-Ornithine monochlorohydrate/ornithine is a L-alpha-amino acid.
Names & identifiers
- Preferred name
- Ornithine hydrochloride
- IUPAC
- (2S)-2,5-diaminopentanoic acid;hydrochloride
- English name
- L(+)-Ornithine hydrochloride
- Molecular formula
- C5H13ClN2O2
- Molecular weight
- 168.62
Names & synonyms
L-Ornithine hydrochlorideL-Ornithine monohydrochlorideL-Ornithine, monohydrochlorideOrnithine monohydrochlorideOrnithine hydrochlorideOrnithine hydrochloride (VAN)Ornithine L monochlorohydrateL-Ornithine hydrochloride (VAN)L-(+)-2,5-Diaminopentanoic acidEINECS 221-678-6HBK84K66XHNSC 118360
Show more names
L-ORNITHINE HCLD-ORNITHINE HYDROCHLORIDED-ORNITHINE HCL(S)-2,5-DIAMINOPENTANOIC ACID HYDROCHLORIDEOrn.HClL-Ornithine HCI
ORNITHINE HCLAI3-52601Ornithine, monohydrochloride, L-L-Ornithine, hydrochloride (1:1)FEMA NO. 4190L-ORNITHINE MONOCHLOROHYDRATE/ORNITHINEDTXSID50858851L-(+)-Ornithine Monohydrochloride
Database identifiers
- CAS
3184-13-2- PubChem CID
- 76654
- DTXSID
DTXSID50858851
Properties
Computed structural properties
- Topological polar surface area
- 89.3 Ų
- Hydrogen bond donors
- 4
- Hydrogen bond acceptors
- 4
- Rotatable bonds
- 4
- Heavy atoms
- 10
- Formal charge
- 0
- Complexity
- 95
Experimental & physicochemical properties
Chemical ClassesBiological Agents -> Amino Acids and Derivatives
CosmeticsSkin conditioning
Food AdditivesFLAVORING AGENT OR ADJUVANT -> FDA Substance added to food
Solubility
Soluble in water
Very slightly soluble (in ethanol)
Physical Description
White powder; [Sigma-Aldrich MSDS]
White crystalline solid or powder to syrup; Slight savoury aroma
Physicochemical properties
- Melting point
- 245 °C · 245 °C (dec.)(lit.)
- alpha
- 24 · 24 º (c=4, 6N HCl)
- Density
- 1.57 · 1.57
- bulk density
- 470 kg/m3 · 470kg/m3
- refractive index
- 24 ° · 24 ° (C=4, 6mol/L HCl)
- FEMA
- 4190 · 4190 | L-ORNITHINE MONOCHLOROHYDRATE/ORNITHINE
Safety & regulation
GHS classification
GHS Classification
This chemical does not meet GHS hazard criteria for 86.9% (313 of 360) of all reports.
Warning
H319 (13.1%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]
P264+P265, P280, P305+P351+P338, and P337+P317 (click each P-code to see the statement)
Aggregated GHS information provided per 360 reports by companies from 3 notifications to the ECHA C&L Inventory.
Hazard information
Regulatory Information
Chemical: L-Ornithine, monohydrochloride
Status: Active Update: 29-08-2022 https://echa.europa.eu/registration-dossier/-/registered-dossier/21518
ornithine hydrochloride: Does not have an individual approval but may be used under an appropriate group standard
Other Safety InformationIMAP assessments - L-Ornithine, monohydrochloride: Environment tier I assessment
Hazards Summary
Causes altered sleep time (including change in righting reflex), ataxia, and dyspnea in oral lethal-dose studies of rats; [RTECS] Safe when used as a flavoring agent in food; [JECFA] A strong eye irritant; [Sigma-Aldrich MSDS] See Ornithine.
Hazard Classes and CategoriesEye Irrit. 2A (13.1%)
Safety data
- F
- 3-10
- wgk
- 3
- tsca
- TSCA listed
- rtecs
- RM2985000
- hs_code
- 29224995
- Toxicity
- LD50 orl-rat: 10 g/kg JPMSAE 62,49,73
- risk_code
- 36/37/38-36
Chemistry & industry
Uses & manufacturing
UsesUsed as a flavoring agent; [FDA]
Use Classification
Flavoring Agents -> JECFA Flavorings Index
Cosmetics -> Skin conditioning
General Manufacturing InformationL-Ornithine, hydrochloride (1:1): ACTIVE
Applications
UsesL(+)-Ornithine hydrochloride is a nonprotein amino acid used in the biosynthesis of L-arginine, L-proline and polyamines.
UsesL(+)-Ornithine hydrochloride is a non-essential amino acid for human development but is required intermediate in arginine biosynthesis. L(+)-Ornithine hydrochloride is found in virtually all vertebrate tissues as well as incorporated into proteins, such as tyrocidine. Isolation from chicken excreta.
UsesNon-essential amino acid for human development but is required intermediate in arginine biosynthesis. Found in virtually all vertebrate tissues as well as incorporated into proteins, such as tyrocidine. Isolation from chicken excreta.
General DescriptionL-Ornithine is the functional metabolite of L-arginine.
Upstream & downstream products
Upstream raw materials
Related reactions
26 records
Compound notes
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