5-Hydroxyoxindole
Completing data — refresh the page later to see the latest
Basic information
- CAS
3416-18-0- Standard SMILES
O=C1Cc2cc(O)ccc2N1- InChIKey
ZGTUSQAQXWSMDW-UHFFFAOYSA-N- Molecular formula
- C8H7NO2
- Average molar mass
- 149.15 g/mol
- Monoisotopic mass
- 149.04767847
Names & identifiers
- Preferred name
- 5-Hydroxyoxindole
- IUPAC
- 5-hydroxy-1,3-dihydroindol-2-one
- English name
- 5-Hydroxyoxindole
- Molecular formula
- C8H7NO2
- Molecular weight
- 149.15
Names & synonyms
5-Hydroxyoxindole3416-18-05-hydroxy-1,3-dihydroindol-2-one2,3-Dihydro-5-hydroxyindol-2-oneDTXSID20187761RefChem:442352DTXCID80110252222-309-15-hydroxyindolin-2-oneMFCD000145665-Hydroxy-1,3-dihydro-indol-2-one5-Hydroxy-1,3-dihydro-2H-indol-2-one
Show more names
5-HYDROXY-2-INDOLINONE1H-indole-5-peroxol5-hydroxyindol-2-oneSunitinib Impurity 675-hydroxyindole-2-one
5-hydroxy-2,3-dihydro-1H-indol-2-one2H-Indol-2-one, 1,3-dihydro-5-hydroxy-5-HYDROXY-2-OXYINDOLE5-Hydroxy-2-oxindole2-Indolinone, 5-hydroxy-5-hydroxy-oxindole5-hydroxyindolinoneEINECS 222-309-1
Database identifiers
- CAS
3416-18-0- PubChem CID
- 76955
- DTXSID
DTXSID20187761- ChEMBL
CHEMBL3093623- ChEBI
CHEBI:230711- EC Number
- 222-309-1
- Nikkaji
- J182A
Properties
Computed structural propertiesFilling in
- XLogP
- 0.8
- Topological polar surface area
- 49.3 Ų
- Hydrogen bond donors
- 2
- Hydrogen bond acceptors
- 2
- Rotatable bonds
- 0
- Heavy atoms
- 11
- Formal charge
- 0
- Complexity
- 181
Physicochemical properties
- Melting point
- 156 · 156-157 °C(Solv: ethanol (64-17-5))
- Boiling point
- 419.9 · 419.9±45.0 °C(Predicted)
- Density
- 1.362 · 1.362±0.06 g/cm3(Predicted)
- storage temp.
- -20 °C · Store at -20°C
- form
- Solid
- pka
- 9 · 9+-.0.20(Predicted)
- color
- Light brown to brown
- InChI
- 1S/C8H7NO2/c10-6-1-2-7-5(3-6)4-8(11)9-7/h1-3,10H,4H2,(H,9,11)
- InChIKey
- ZGTUSQAQXWSMDW-UHFFFAOYSA-N
- SMILES
- Oc1ccc2NC(=O)Cc2c1
- CAS DataBase Reference
- 3416 · 3416-18-0(CAS DataBase Reference)
- UNSPSC Code
- 12352200 · 12352200
- Symbol(GHS)
- 7 · GHS07
- Signal word
- Warning
- Hazard statements
- 319 · H319-H315-H335-H302
Safety & regulation
Safety information is for reference only and does not replace the supplier’s Safety Data Sheet (SDS), applicable regulations, or professional assessment.
GHS classification
GHS Classification
Warning
H302 (100%): Harmful if swallowed [Warning Acute toxicity, oral]；H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]；H319 (100%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]；H335 (100%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation]
P261, P264, P264+P265, P270, P271, P280, P301+P317, P302+P352, P304+P340, P305+P351+P338, P319, P321, P330, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501 (click each P-code to see the statement)
The GHS information provided by 1 company from 1 notification to the ECHA C&L Inventory.
Hazard information
Hazard Classes and CategoriesAcute Tox. 4 (100%)；Skin Irrit. 2 (100%)；Eye Irrit. 2A (100%)；STOT SE 3 (100%)
Safety data
- wgk
- WGK 3
- hs_code
- 2933998090
- risk_code
- 43
- Signal word
- Warning
- Symbol(GHS)
- GHS07
- safety_code
- 36/37
- Storage Class
- 11 - Combustible Solids
- Hazard statements
- H319-H315-H335-H302
- Precautionary statements
- P264-P270-P301+P312-P330-P501-P264-P280-P302+P352-P321-P332+P313-P362-P264-P280-P305+P351+P338-P337+P313P
Chemistry & industry
Applications
Uses5-Hydroxyoxindole is a structural analog of uric acid. 5-Hydroxyoxindole has DPPH radical scavenging activities and lipid peroxidation-inhibitory activities. 5-Hydroxyoxindole can be used for the research of oxidative stress-mediated disorders[1].
Upstream & downstream products
Upstream raw materials
Suppliers
Loading…
Open inquiries
Loading…
Related reactions
8 records
Compound notes
Loading…