1,3-Benzenediamine, N1,N1-dimethyl-, hydrochloride (1:2) (HCID 77124)

Names & identifiers

Preferred name: 1,3-Benzenediamine, N1,N1-dimethyl-, hydrochloride (1:2)
IUPAC: 3-N,3-N-dimethylbenzene-1,3-diamine;dihydrochloride
English name: N,N-Dimethyl-m-phenylenediamine dihydrochloride
Molecular formula: C8H14Cl2N2
Molecular weight: 209.12

Names & synonyms

N,N-Dimethyl-m-phenylenediamine dihydrochloride1,3-Benzenediamine, N,N-dimethyl-, dihydrochlorideN,N-Dimethylbenzene-1,3-diamine dihydrochlorideEINECS 222-693-0NSC 87900DTXSID9063089m-Phenylenediamine, N,N-dimethyl-, dihydrochloride1,3-Benzenediamine, N1,N1-dimethyl-, hydrochloride (1:2)RefChem:412873DTXCID3039086222-693-03575-32-4

Show more names

3-Dimethylaminoaniline2HClN,N-Dimethyl-m-phenylenediamine2HClN,N-DIMETHYL-M-PHENYLENEDIAMINE DI HCLM-[DIMETHYLAMINO]ANILINE DIHYDROCHLORIDEN N-DIMETHYL-M-PHENYLENEDIAMINE DIHYDROC3-(DIMETHYLAMINO)ANILINE DIHYDROCHLORIDE3-AMINO-N,N-DIMETHYLANILINE DIHYDROCHLORIDE3-benzenediamine,n,n-dimethyl-dihydrochlorideN,N-DIMETHYL-M-PHENYLENEDIAMMONIUM DICHLORIDE

N1,N1-Dimethylbenzene-1,3-diamine dihydrochlorideN,N-Dimethyl-1,3-phenylenediamine dihydrochlorideMFCD00012971N,N-Dimethyl-m-phenylenediamine, DihydrochlorideN,N-dimethyl-1,3-benzenediamine dihydrochlorideN,N-Dimethyl-m-phenylenediaminedihydrochlorideSCHEMBL55144STR02355

Database identifiers

CAS: 3575-32-4
PubChem CID: 77124
DTXSID: DTXSID9063089
EC Number: 222-693-0

Properties

Computed structural properties

Topological polar surface area: 29.3 Å²
Hydrogen bond donors: 3
Hydrogen bond acceptors: 2
Rotatable bonds: 1
Heavy atoms: 12
Formal charge: 0
Complexity: 101

Physicochemical properties

Melting point: 217 · 217-220 °C (dec.)
storage temp.: Keep in dark place,Inert atmosphere,Room temperature
solubility: 100 mg/2ml, · water: soluble100mg/2ml, clear to slightly hazy (faintly yellow to tan to purple)
form: crystalline
color: off-white to tan
Water Solubility: Soluble in water, chloroform and dichloromethane. Slightly soluble in ethyl acetate.
BRN: 3694384 · 3694384
Stability: Stable. Incompatible with acids, oxidising agents.
InChI: 1S/C8H12N2.2ClH/c1-10(2)8-5-3-4-7(9)6-8;;/h3-6H,9H2,1-2H3;2*1H
InChIKey: BZJPIQKDEGXVFG-UHFFFAOYSA-N
SMILES: Cl.Cl.CN(C)c1cccc(N)c1
CAS DataBase Reference: 3575 · 3575-32-4(CAS DataBase Reference)
EPA Substance Registry System: 1 · 1,3-Benzenediamine, N,N-dimethyl-, dihydrochloride (3575-32-4)
UNSPSC Code: 12352200 · 12352200
NACRES: 22 · NA.22
Symbol(GHS): 6 · GHS06
Signal word: Danger
Hazard statements: 301 · H301-H315-H317-H319-H335
Precautionary statements: 280 · P280-P301+P310+P330-P302+P352-P305+P351+P338
target organs: Respiratory system
PPE: 2 · Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges
Hazard Codes: T,Xi
Risk Statements: 25 · 25-36/37/38-43-23/24/25
Safety Statements: 36 · 36/37/39-45-26-36/37
RIDADR: 2811 · UN 2811 6.1/PG 2
WGK Germany: 3 · 3
F: 3 · 3-8-10
TSCA: TSCA listed
HazardClass: 6.1 · 6.1
PackingGroup: III
HS Code: 29215900 · 29215900
Storage Class: 6.1 C · 6.1C - Combustible acute toxic Cat.3toxic compounds or compounds which causing chronic effects
Hazard Classifications: 3 OralEye · Acute Tox. 3 OralEye Irrit. 2Skin Irrit. 2Skin Sens. 1STOT SE 3
Limited Quantities: 5 L · 5.0 L (1.3 gallons) (liquid) or 5.0 kg (11 lbs) (solid)
Excepted Quantities: Max Inner Pack (30g or 30ml) and Max Outer Pack (1Kg or 1L)

Safety & regulation

GHS classification

GHS Classification · 5 items

Danger

H301 (100%): Toxic if swallowed [Danger Acute toxicity, oral]；H311 (13.3%): Toxic in contact with skin [Danger Acute toxicity, dermal]；H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]；H317 (86.7%): May cause an allergic skin reaction [Warning Sensitization, Skin]；H319 (100%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]；H335 (100%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation]

P261, P262, P264, P264+P265, P270, P271, P272, P280, P301+P316, P302+P352, P304+P340, P305+P351+P338, P316, P319, P321, P330, P332+P317, P333+P317, P337+P317, P361+P364, P362+P364, P403+P233, P405, and P501 (click each P-code to see the statement)

Aggregated GHS information provided per 45 reports by companies from 5 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.；Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website.

Hazard information

Regulatory Information · 2 items

Chemical: 1,3-Benzenediamine, N,N-dimethyl-, dihydrochloride

1,3-Benzenediamine, N,N-dimethyl-, dihydrochloride: Does not have an individual approval but may be used under an appropriate group standard

Other Safety InformationEvaluation - Chemicals not considered for in depth evaluation - Not commercially active in Australia

Hazard Classes and CategoriesAcute Tox. 3 (100%)；Acute Tox. 3 (13.3%)；Skin Irrit. 2 (100%)；Skin Sens. 1 (86.7%)；Eye Irrit. 2 (100%)；STOT SE 3 (100%)

Regulatory information

Regulatory Information · 2 items

Chemical: 1,3-Benzenediamine, N,N-dimethyl-, dihydrochloride

1,3-Benzenediamine, N,N-dimethyl-, dihydrochloride: Does not have an individual approval but may be used under an appropriate group standard

Safety data

F: 3-8-10
PPE: Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges
wgk: 3
tsca: TSCA listed
ridadr: UN 2811 6.1/PG 2
hs_code: 29215900
risk_code: 25-36/37/38-43-23/24/25
Signal word: Danger
Symbol(GHS): GHS06
hazard_code: T,Xi
safety_code: 36/37/39-45-26-36/37
hazard_class: 6.1
Storage Class: 6.1C - Combustible acute toxic Cat.3toxic compounds or compounds which causing chronic effects
packing_group: III
target organs: Respiratory system
Hazard statements: H301-H315-H317-H319-H335
Limited Quantities: 5.0 L (1.3 gallons) (liquid) or 5.0 kg (11 lbs) (solid)
Excepted Quantities: Max Inner Pack (30g or 30ml) and Max Outer Pack (1Kg or 1L)
Hazard Classifications: Acute Tox. 3 OralEye Irrit. 2Skin Irrit. 2Skin Sens. 1STOT SE 3
Precautionary statements: P280-P301+P310+P330-P302+P352-P305+P351+P338

Chemistry & industry

Uses & manufacturing

General Manufacturing Information1,3-Benzenediamine, N1,N1-dimethyl-, hydrochloride (1:2): INACTIVE

Applications · 2 items

Usesit can be used to produce N-(4,5,6-trimethoxy-2,4-dimethyl-tetrahydro-pyran-3-yl)-formamide with 4,5,6-trimethoxy-2,4-dimethyl-tetrahydro-pyran-3-ylamine. This reaction will need solvent tetrahydrofuran. it is applied as a selective formylating agent for one of two amino groups in such basic amino acids as ornithine or lysine.

UsesN,N-Dimethyl-1,3-phenylenediamine dihydrochloride (3-Amino-N,N-dimethylaniline dihydrochloride) was used in the preparation of a dimethylamino-aniline derivative.