Basic information
- CAS
3691-21-2- Standard SMILES
NC(=O)C(CCN1CCCCCC1)(c1ccccc1)c1ccccc1- InChIKey
SLJXUJZUTPFXRJ-UHFFFAOYSA-N- Molecular formula
- C22H28N2O
- Average molar mass
- 336.5 g/mol
- Monoisotopic mass
- 336.22016352
Overview
Buzepide is a member of the class of azepanes that is 2-phenylacetamide in which the methylene hydrogens at position 2 are replaced by a phenyl group and an aminocarbonyl group. It inhibits gastric juice secretion. It has a role as a cholinergic antagonist and a mydriatic agent. It is a primary carboxamide, a member of benzenes, a member of azepanes and a tertiary amino compound. It is a conjugate base of a buzepide(1+).
Names & identifiers
- Preferred name
- Buzepide
- IUPAC
- 4-(azepan-1-yl)-2,2-diphenylbutanamide
- English name
- hexahydro-alpha,alpha-diphenyl-1H-azepine-1-butyramide
- Molecular formula
- C22H28N2O
- Molecular weight
- 336.47
Names & synonyms
BuzepideBuzepidonum4-(azepan-1-yl)-2,2-diphenylbutanamideHexahydro-alpha,alpha-diphenyl-1H-azepine-1-butyramidehexamethamidemydriamideAcemydriteCalmacidUNII-44FN6UP52644FN6UP526BUZEPIDE [MI]EINECS 223-002-5
Show more names
-diphenyl-1H-azepine-1-butyramide4-(1-azepanyl)-2,2-diphenylbutanamideHexahydro-α,α-diphenyl-1H-azepine-1-butanamide1H-Azepine-1-butanamide, hexahydro-α,α-diphenyl-
BUZEPIDE [WHO-DD]Hexahydro-alpha,alpha-diphenyl-1H-azepine-1-butanamide2,2-diphenyl-4-hexamethyleneiminobutyramideCHEBI:157619DTXSID90190388R-6584-(hexahydro-1H-azepinyl)-2,2-diphenylbutanamideHEXAHYDRO-.ALPHA.,.ALPHA.-DIPHENYL-1H-AZEPINE-1-BUTANAMIDE
Database identifiers
- CAS
3691-21-2- PubChem CID
- 77274
- DTXSID
DTXSID90190388- ChEMBL
CHEMBL2110808- ChEBI
CHEBI:157619
Properties
Computed structural properties
- XLogP
- 3.8
- Topological polar surface area
- 46.3 Ų
- Hydrogen bond donors
- 1
- Hydrogen bond acceptors
- 2
- Rotatable bonds
- 6
- Heavy atoms
- 25
- Formal charge
- 0
- Complexity
- 384
Physicochemical properties
- Melting point
- 141.5 · 141.5-143.5°
- FDA UNII
- 44 FN6UP526 · 44FN6UP526
Chemistry & industry
Suppliers1 total
陕西缔都医药有限责任公司81148925 17391631969 · [email protected]
Additional notes
DefinitionChEBI: Buzepide is a member of the class of azepanes that is 2-phenylacetamide in which the methylene hydrogens at position 2 are replaced by a phenyl group and an aminocarbonyl group. It inhibits gastric juice secretion. It has a role as a mydriatic agent and a cholinergic antagonist. It is a member of azepanes, a primary carboxamide, a member of benzenes and a tertiary amino compound. It is a conjugate base of a buzepide(1+).
Related reactions
0 records
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Compound notes
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