2-Propynoxyethanol

HCID 77596

Basic information

CAS
3973-18-0
Standard SMILES
C#CCOCCO
InChIKey
GHGCQQRMJCSIBQ-UHFFFAOYSA-N
Molecular formula
C5H8O2
Average molar mass
100.12 g/mol
Monoisotopic mass
100.05242949

Names & identifiers

Preferred name
2-Propynoxyethanol
IUPAC
2-prop-2-ynoxyethanol
English name
Propynol ethoxylate
Molecular formula
C5H8O2
Molecular weight
100.12

Names & synonyms

3973-18-0Ethanol, 2-(2-propynyloxy)-2-(Prop-2-yn-1-yloxy)ethanol2-Propynoxyethanol2-(2-Propyn-1-yloxy)ethanol2-(2-Propynyloxy)ethanolEthylene glycol monopropargyl ether2-(Propargyloxy)ethanol3-(2-hydroxyethoxy)-1-propyneUNII-2EQ7D0F9DREthanol, 2-(2-propyn-1-yloxy)-2EQ7D0F9DR
Show more names
PME2-(prop-2-yn-1-yloxy)ethan-1-olCOBethoxyL2-(prop-2-ynyloxy)ethanolpropargyl alcohol ethoxylateCSTB
4-Oxa-1-hexyn-6-olEINECS 223-601-1DTXSID9044665RefChem:89342DTXCID7024665223-601-1GHGCQQRMJCSIBQ-UHFFFAOYSA-NPropynol ethoxylate

Database identifiers

CAS
3973-18-0
PubChem CID
77596
DTXSID
DTXSID9044665
UNII
2EQ7D0F9DR
EC Number
223-601-1
Nikkaji
J113.065J

Properties

Computed structural properties

XLogP
-0.5
Topological polar surface area
29.5 Ų
Hydrogen bond donors
1
Hydrogen bond acceptors
2
Rotatable bonds
3
Heavy atoms
7

Physicochemical properties

Boiling point
80 · 80-90 °C(Press: 12-14 Torr)
Density
1.0261 · 1.0261
refractive index
1.4502 · 1.4502
storage temp.
-20 °C · Sealed in dry,Store in freezer, under -20°C
solubility
Chloroform (Sparingly), Ethyl Acetate (Slightly)
form
Oil

Safety & regulation

GHS classification

GHS Classification · 6 items

This chemical does not meet GHS hazard criteria for 6.1% (10 of 163) of reports.

Danger

H302 (81%): Harmful if swallowed [Warning Acute toxicity, oral];H318 (64.4%): Causes serious eye damage [Danger Serious eye damage/eye irritation];H319 (29.4%): Causes serious eye irritation [Warning Serious eye damage/eye irritation];H330 (64.4%): Fatal if inhaled [Danger Acute toxicity, inhalation];H332 (13.5%): Harmful if inhaled [Warning Acute toxicity, inhalation];H335 (65.6%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation];H361f (64.4%): Suspected of damaging fertility [Warning Reproductive toxicity];H373 (64.4%): May causes damage to organs through prolonged or repeated exposure [Warning Specific target organ toxicity, repeated exposure]

P203, P260, P261, P264, P264+P265, P270, P271, P280, P284, P301+P317, P304+P340, P305+P351+P338, P305+P354+P338, P316, P317, P318, P319, P320, P330, P337+P317, P403+P233, P405, and P501 (click each P-code to see the statement)

Aggregated GHS information provided per 163 reports by companies from 9 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.;Reported as not meeting GHS hazard criteria per 10 of 163 reports by companies.;There are 8 notifications provided by 153 of 163 reports by companies with hazard statement code(s).;Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website.

Hazard information

Regulatory Information · 2 items

Chemical: Ethanol, 2-(2-propynyloxy)-

Ethanol, 2-(2-propynyloxy)-: Does not have an individual approval but may be used as a component in a product covered by a group standard. It is not approved for use as a chemical in its own right.

Hazard Classes and CategoriesAcute Tox. 4 (81%);Eye Dam. 1 (64.4%);Eye Irrit. 2 (29.4%);Acute Tox. 2 (64.4%);Acute Tox. 4 (13.5%);STOT SE 3 (65.6%);Repr. 2 (64.4%);STOT RE 2 (64.4%)

Regulatory information

Regulatory Information · 2 items

Chemical: Ethanol, 2-(2-propynyloxy)-

Ethanol, 2-(2-propynyloxy)-: Does not have an individual approval but may be used as a component in a product covered by a group standard. It is not approved for use as a chemical in its own right.

Safety data

wgk
WGK 1
tsca
TSCA listed
hs_code
2909498090
risk_code
36
Signal word
Warning
Symbol(GHS)
GHS07

Chemistry & industry

Uses & manufacturing

General Manufacturing InformationEthanol, 2-(2-propyn-1-yloxy)-: ACTIVE
Applications · 3 items

DescriptionPropargyl-PEG2-alcohol has propargyl and alcohol end groups. The propargyl can participate in copper-catalyzed Click Chemistry reactions with azides.

UsesPropynol Ethoxylate is an intermediate and it is shown to be used in the design and synthesis of a tag-free chemical probe for photoafiinity labeling.

General DescriptionPropynol ethoxylate, known as 2-propyn-1-ol, is a colourless flammable liquid with a pleasant odour. This volatile organic compound (VOC) occurs naturally in plants and animals and can also be synthesised in a laboratory environment. Propargyl alcohol polyoxyethylene ether has a wide range of applications and plays an important role in scientific research and industrial processes. It is used as a fuel, solvent and reagent in chemical reactions, as well as an important ingredient in the manufacture of many pharmaceuticals and industrial products. In scientific research, it is used as a reagent in organic synthesis, as a solvent in analytical chemistry and as a fuel in combustion studies.

Suppliers100 total

郑州阿尔法化工有限公司+86-18530059196 · [email protected]
衢州润东化工有限公司0570-8789886 18892685668 · [email protected]
南通润丰石油化工有限公司66017690 19952660367 · [email protected]
武汉科美沃化工有限公司+86-2785736489 +8618171418573 · [email protected]
武汉博莱特化工有限公司+86-027-85583407 +86-13554014698 · [email protected]

Related reactions

9 records

Compound notes

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