Phenylpiperazine dihydrochloride
Basic information
- CAS
4004-95-9- Standard SMILES
Cl.Cl.c1ccc(N2CCNCC2)cc1- InChIKey
CUTPTQNQXVVRDB-UHFFFAOYSA-N- Molecular formula
- C10H16Cl2N2
- Average molar mass
- 235.15 g/mol
- Monoisotopic mass
- 234.0690539
Names & identifiers
- Preferred name
- Phenylpiperazine dihydrochloride
- IUPAC
- 1-phenylpiperazine;dihydrochloride
- English name
- 1-Phenylpiperazine dihydrochloride
- Molecular formula
- C10H16Cl2N2
- Molecular weight
- 235.15
Names & synonyms
phenylpiperazine dihydrochlorideRefChem:770051-Phenylpiperazine dihydrochloride4004-95-91-phenylpiperazine;dihydrochloridePiperazine, 1-phenyl-, dihydrochloridePHENYLPIPERAZINE (HYDROCHLORIDE)T8Y494LR4WMFCD000352831-Phenylpiperazine HClNSC-150847EINECS 223-654-0
Show more names
Nsc1508471-Phenylpiperazine2HCl1-Phenylpiperazine hHdrochlorideN-Phenylpiperazine Dihydrochloride4-Phenylpiperazine Dihydrochloride1-PHENYLPIPERAZINE DIHYDROCHLORIDE 98%
1-Phenylpiperazine DiHClUNII-T8Y494LR4WSCHEMBL11553805N-PHENYLPIPERAZINE DI-HCLDTXSID40193102EAA00495AKOS024015101HY-W012179
Database identifiers
- CAS
4004-95-9- PubChem CID
- 77619
- DTXSID
DTXSID40193102- UNII
- T8Y494LR4W
- EC Number
- 223-654-0
Properties
Computed structural properties
- Topological polar surface area
- 15.3 Ų
- Hydrogen bond donors
- 3
- Hydrogen bond acceptors
- 2
- Rotatable bonds
- 1
- Heavy atoms
- 14
- Formal charge
- 0
- Complexity
- 124
Physicochemical properties
- Melting point
- 221 · 221-223°C
- storage temp.
- Hygroscopic, Refrigerator, Under Inert Atmosphere
- solubility
- DMSO (Slightly), Methanol (Slightly), Water (Slightly)
- form
- Solid
- color
- White to Off-White
- Stability
- Hygroscopic
- FDA UNII
- 8 Y494LR4W · T8Y494LR4W
- Symbol(GHS)
- 7 · GHS07
- Signal word
- Warning
- Hazard statements
- 335 · H335-H319-H315
- Precautionary statements
- 264 · P264-P280-P305+P351+P338-P337+P313P-P264-P280-P302+P352-P321-P332+P313-P362
Safety & regulation
Safety information is for reference only and does not replace the supplier’s Safety Data Sheet (SDS), applicable regulations, or professional assessment.
GHS classification
GHS Classification
Warning
H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]
P261, P264, P264+P265, P271, P280, P302+P352, P304+P340, P305+P351+P338, P319, P321, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501 (click each P-code to see the statement)
Aggregated GHS information provided per 39 reports by companies from 2 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.
Hazard information
Regulatory InformationPiperazine, 1-phenyl-, dihydrochloride: Does not have an individual approval but may be used as a component in a product covered by a group standard. It is not approved for use as a chemical in its own right.
Hazard Classes and CategoriesSkin Irrit. 2 (100%)
Safety data
- Signal word
- Warning
- Symbol(GHS)
- GHS07
- Hazard statements
- H335-H319-H315
- Precautionary statements
- P264-P280-P305+P351+P338-P337+P313P-P264-P280-P302+P352-P321-P332+P313-P362
Chemistry & industry
Pharmacology
MeSH Pharmacological Classification
Drugs that bind to but do not activate alpha-adrenergic receptors thereby blocking the actions of endogenous or exogenous adrenergic agonists. Adrenergic alpha-antagonists are used in the treatment of hypertension, vasospasm, peripheral vascular disease, shock, and pheochromocytoma.
A loosely defined grouping of drugs that have effects on psychological function. Here the psychotropic agents include the antidepressive agents, hallucinogens, and tranquilizing agents (including the antipsychotics and anti-anxiety agents).
Applications
Uses1-Phenylpiperazine was tested for its activity as a topical glaucoma agent.
Suppliers
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Related reactions
1 records
Compound notes
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