CAS 4447-60-3 Propane, 2,2',2''-[methylidynetris(oxy)]tris- (HCID 78191)

Names & identifiers

Preferred name: Propane, 2,2',2''-[methylidynetris(oxy)]tris-
IUPAC: 2-[di(propan-2-yloxy)methoxy]propane
English name: Triisopropyl orthoformate
Molecular formula: C10H22O3
Molecular weight: 190.28

Names & synonyms

TriisopropylorthoformatePropane, 2,2',2''-[methylidynetris(oxy)]tris-EINECS 224-688-9DTXSID7063479Propane, 2,2',2''-(methylidynetris(oxy))tris-2,2',2''-(Methylidynetris(oxy))trispropane2,2',2''-[methylidynetris(oxy)]trispropaneRefChem:868830DTXCID5040334224-688-9Triisopropyl orthoformate4447-60-3

Show more names

TIPOFTIPOProformate triisopropylTri(2-propyl)orthoformateTriisopropylOrthoformate>2-diisopropoxymethoxy-propaneTriisopropyl orthoformate,95%

Triisopropoxymethane2-(Diisopropoxymethoxy)propane2-[di(propan-2-yloxy)methoxy]propaneMFCD00060628Orthoformic Acid Triisopropyl EsterIsopropyl orthoformate2-[bis(propan-2-yloxy)methoxy]propaneOrthoformic acid, triisopropyl ester

Database identifiers

CAS: 4447-60-3
PubChem CID: 78191
DTXSID: DTXSID7063479
EC Number: 224-688-9
Nikkaji: J121.635J

Properties

Computed structural properties

XLogP: 2.4
Topological polar surface area: 27.7 Å²
Hydrogen bond donors: 0
Hydrogen bond acceptors: 3
Rotatable bonds: 6
Heavy atoms: 13
Formal charge: 0
Complexity: 97.6

Experimental & physicochemical properties

SpringerMaterials PropertiesOptical coefficient

Physicochemical properties

Boiling point: 65 · 65-66 °C/18 mmHg (lit.)
Density: 0.854 g/mL · 0.854 g/mL at 25 °C (lit.)
refractive index: 20 · n20/D 1.397(lit.)
Flash point: 108 °F · 108 °F
storage temp.: Flammables area
form: Liquid
color: Clear colorless
Sensitive: Moisture Sensitive
BRN: 1700668 · 1700668
InChI: InChI=1S/C10H22O3/c1-7(2)11-10(12-8(3)4)13-9(5)6/h7-10H,1-6H3
InChIKey: FPIVAWNGRDHRSQ-UHFFFAOYSA-N
SMILES: C(OC(C)C)(OC(C)C)OC(C)C
CAS DataBase Reference: 4447 · 4447-60-3(CAS DataBase Reference)
EPA Substance Registry System: 2 · Propane, 2,2',2''-[methylidynetris(oxy)]tris- (4447-60-3)
UNSPSC Code: 12352100 · 12352100
NACRES: 22 · NA.22
Symbol(GHS): 2 · GHS02,GHS07
Signal word: Warning
Hazard statements: 226 · H226-H315-H319-H335
Precautionary statements: 210 · P210-P302+P352-P305+P351+P338
target organs: Respiratory system
PPE: Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter
Hazard Codes: Xi
Risk Statements: 10 · 10-36/37/38
Safety Statements: 26 · 26-36-37/39-16
RIDADR: 3272 · UN 3272 3/PG 3
WGK Germany: 1 · 1
F: 21 · 21
TSCA: TSCA listed
HazardClass: 3 · 3
PackingGroup: III
HS Code: 29159000 · 29159000
Storage Class: 3 · 3 - Flammable liquids
Hazard Classifications: 2 Flam · Eye Irrit. 2Flam. Liq. 3Skin Irrit. 2STOT SE 3

Safety & regulation

GHS classification

GHS Classification · 4 items

Warning

H226 (100%): Flammable liquid and vapor [Warning Flammable liquids]

P210, P233, P240, P241, P242, P243, P261, P264, P264+P265, P271, P280, P302+P352, P303+P361+P353, P304+P340, P305+P351+P338, P319, P321, P332+P317, P337+P317, P362+P364, P370+P378, P403+P233, P403+P235, P405, and P501 (click each P-code to see the statement)

Aggregated GHS information provided per 49 reports by companies from 7 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

Hazard information

Regulatory Information · 2 items

PMN - indicates a commenced PMN (Pre-Manufacture Notices) substance.

Propane, 2,2',2''-[methylidynetris(oxy)]tris-: Does not have an individual approval but may be used as a component in a product covered by a group standard. It is not approved for use as a chemical in its own right.

Hazard Classes and CategoriesFlam. Liq. 3 (100%)

Safety data

F: 21
PPE: Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter
wgk: 1
tsca: TSCA listed
ridadr: UN 3272 3/PG 3
hs_code: 29159000
risk_code: 10-36/37/38
Signal word: Warning
Symbol(GHS): GHS02,GHS07
hazard_code: Xi
safety_code: 26-36-37/39-16
hazard_class: 3
Storage Class: 3 - Flammable liquids
packing_group: III
target organs: Respiratory system
Hazard statements: H226-H315-H319-H335
Hazard Classifications: Eye Irrit. 2Flam. Liq. 3Skin Irrit. 2STOT SE 3
Precautionary statements: P210-P302+P352-P305+P351+P338

Chemistry & industry

Uses & manufacturing

General Manufacturing InformationPropane, 2,2',2''-[methylidynetris(oxy)]tris-: ACTIVE

Applications · 3 items

UsesTriisopropyl Orthoformate (cas# 4447-60-3) is a compound useful in organic synthesis.

UsesTriisopropyl orthoformate may be used for the preparation of 2-(diisopropoxymethyl)oxirane.

General DescriptionTriisopropyl orthoformate (TIPO) is formed during the reaction of dichlorofluoromethane with potassium isopropoxide in isopropyl alcohol. Separation of TIPO from n-hexane by dense carbon nanotube (CNT) membranes by pervaporation has been reported.