Basic information
- CAS
332-77-4- Standard SMILES
COC1C=CC(OC)O1- InChIKey
WXFWXFIWDGJRSC-UHFFFAOYSA-N- Molecular formula
- C6H10O3
- Average molar mass
- 130.14 g/mol
- Monoisotopic mass
- 130.06299418
Names & identifiers
- Preferred name
- 2,5-Dihydro-2,5-dimethoxyfuran
- IUPAC
- 2,5-dimethoxy-2,5-dihydrofuran
- English name
- 2,5-Dihydro-2,5-dimethoxyfuran
- Molecular formula
- C6H10O3
- Molecular weight
- 130.14
Names & synonyms
2,5-Dimethoxy-2,5-dihydrofuran2,5-Dihydro-2,5-dimethoxyfuranFuran, 2,5-dihydro-2,5-dimethoxy-A31695LI9AEINECS 206-367-5NSC 43243NSC-432432,5-Dihydro-2,5-dimethoxyfuran, cis + transDTXSID20870505EC 206-367-5RefChem:4444192,5Dihydro2,5dimethoxyfuran
Show more names
DMDF2,5-Dihydro-2,5-dimethoxyfurane2,5-DIMETH5-Dihydro-25-DimethoxyfuranDiMethoxy-2,5-dihydrodimethoxy dihydrogen furan2,5-DIHYDRO-2,5-DIMETHOXFURAN2,5-dihydro-2,5-dimethoxy-fura
Furan, 2,5dihydro2,5dimethoxyDTXCID00818223206-367-5332-77-4MFCD000032202.5-Dihydro-2.5-dimethoxyfuranNSC43243SCHEMBL301890
Database identifiers
- CAS
332-77-4- PubChem CID
- 78974
- DTXSID
DTXSID20870505- UNII
- A31695LI9A
- EC Number
- 206-367-5
- Nikkaji
- J79.598D
Properties
Computed structural properties
- XLogP
- 0.3
- Topological polar surface area
- 27.7 Ų
- Hydrogen bond donors
- 0
- Hydrogen bond acceptors
- 3
- Rotatable bonds
- 2
- Heavy atoms
- 9
- Formal charge
- 0
- Complexity
- 98.9
Experimental & physicochemical properties
Chemical ClassesOther Classes -> Ethers, Other
SpringerMaterials PropertiesChemical shift
Physical Description
Liquid
Liquid; [Alfa Aesar MSDS]
Physicochemical properties
- Melting point
- -40 °C · <-40°C
- Boiling point
- 160 · 160-162 °C(lit.)
- Density
- 1.073 g/mL · 1.073 g/mL at 25 °C(lit.)
- refractive index
- 20 · n20/D 1.434(lit.)
- Flash point
- 117 °F · 117 °F
- storage temp.
- 30 °C · Store below +30°C.
- solubility
- 2 O; · practically insol H2O; sol MeOH, Et2O, THF
- form
- Liquid
- color
- Clear
- PH
- 6 · 6-7 (200g/l, H2O, 20℃)
- explosive limit
- 1.1 · 1.1-18.3%(V)
- optical activity
- -7.1875 ° · -7.1875°(C=0.2 g/100mL CHCL3)
- BRN
- 113225 · 113225
- InChI
- 1S/C6H10O3/c1-7-5-3-4-6(8-2)9-5/h3-6H,1-2H3
- InChIKey
- WXFWXFIWDGJRSC-UHFFFAOYSA-N
- SMILES
- COC1OC(OC)C=C1
- CAS DataBase Reference
- 332 · 332-77-4(CAS DataBase Reference)
- FDA UNII
- 31695 LI9A · A31695LI9A
- NIST Chemistry Reference
- 2 · Furan, 2,5-dihydro-2,5-dimethoxy-(332-77-4)
- EPA Substance Registry System
- 2 · Furan, 2,5-dihydro-2,5-dimethoxy- (332-77-4)
- UNSPSC Code
- 12352100 · 12352100
- NACRES
- 22 · NA.22
- Symbol(GHS)
- 2 · GHS02,GHS07
- Signal word
- Warning
- Hazard statements
- 226 · H226-H302+H332-H319
- Precautionary statements
- 210 · P210-P233-P240-P301+P312-P304+P340+P312-P305+P351+P338
- PPE
- Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter
- Risk Statements
- 10 · 10
- Safety Statements
- 16 · 16-29-33-24/25
- RIDADR
- 1993 · UN 1993 3/PG 3
- WGK Germany
- 1 · 1
- TSCA
- TSCA listed
- HazardClass
- 3 · 3
- PackingGroup
- III
- HS Code
- 29321900 · 29321900
- Storage Class
- 3 · 3 - Flammable liquids
- Hazard Classifications
- 4 InhalationAcute · Acute Tox. 4 InhalationAcute Tox. 4 OralEye Irrit. 2Flam. Liq. 3
- REACH Registrations
- Active
- Limited Quantities
- 5 L · 5.0 L (1.3 gallons) (liquid)
- Excepted Quantities
- Max Inner Pack (30g or 30ml) and Max Outer Pack (1Kg or 1L)
Safety & regulation
GHS classification
GHS Classification
Warning
H226 (100%): Flammable liquid and vapor [Warning Flammable liquids]
P210, P233, P240, P241, P242, P243, P261, P264, P264+P265, P270, P271, P280, P301+P317, P303+P361+P353, P304+P340, P305+P351+P338, P317, P330, P337+P317, P370+P378, P403+P235, and P501 (click each P-code to see the statement)
Aggregated GHS information provided per 176 reports by companies from 6 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.
Hazard information
Regulatory Information
Furan, 2,5-dihydro-2,5-dimethoxy- is listed on the EPA's Chemical Data Reporting (CDR) system. Manufacturers and importers of Furan, 2,5-dihydro-2,5-dimethoxy- are required to report information about their production and use of this chemical to the EPA under the Toxic Substances Control Act (TSCA). (40 eCFR Part 711)
Status: Active Update: 13-05-2015 https://echa.europa.eu/registration-dossier/-/registered-dossier/11223
2,5-Dihydro-2,5-dimethoxyfuran: Does not have an individual approval but may be used under an appropriate group standard
Hazards SummaryAn irritant; Harmful by ingestion and inhalation; [Alfa Aesar MSDS] See 2,5-Dihydrofuran.
Hazard Classes and CategoriesFlam. Liq. 3 (100%)
Toxicology
Toxicity DataLC50 (rat) = 10,300 mg/m3/4hr
Safety data
- PPE
- Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter
- wgk
- 1
- tsca
- TSCA listed
- ridadr
- UN 1993 3/PG 3
- hs_code
- 29321900
- risk_code
- 10
- Signal word
- Warning
- Symbol(GHS)
- GHS02,GHS07
- safety_code
- 16-29-33-24/25
- hazard_class
- 3
- Storage Class
- 3 - Flammable liquids
- packing_group
- III
- Hazard statements
- H226-H302+H332-H319
- Limited Quantities
- 5.0 L (1.3 gallons) (liquid)
- Excepted Quantities
- Max Inner Pack (30g or 30ml) and Max Outer Pack (1Kg or 1L)
- REACH Registrations
- Active
- Hazard Classifications
- Acute Tox. 4 InhalationAcute Tox. 4 OralEye Irrit. 2Flam. Liq. 3
- Precautionary statements
- P210-P233-P240-P301+P312-P304+P340+P312-P305+P351+P338
Chemistry & industry
Uses & manufacturing
U.S. Production2023: <50,000 lb
Industry UsesIntermediate
General Manufacturing Information
All Other Basic Organic Chemical Manufacturing
Furan, 2,5-dihydro-2,5-dimethoxy-: ACTIVE
Applications
Uses2,5-Dihydro-2,5-dimethoxyfuran, mixture of cis and trans (cas# 332-77-4) is a useful research chemical. It is used in the preparation of 1,1,4,4-tetramethoxy-2-butene.
Preparation methods
Preparationelectrolytic methoxylation of Furan
Upstream & downstream products
Upstream raw materials
Downstream products
Suppliers100 total
北京华美互利生物化工010-56205725 · [email protected]
梯希爱(上海)化成工业发展有限公司021-67121386 · [email protected]
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Dayang Chem (Hangzhou) Co.,Ltd.+86-0571-88938639 17705817739 · [email protected]
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Ark Pharm, Inc.847-367-3680 · [email protected]
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Related reactions
10 records
Compound notes
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