Basic information
- Standard SMILES
OC[C@H]1O[C@H](O)[C@H](O)[C@@H](O)[C@@H]1O- InChIKey
WQZGKKKJIJFFOK-DVKNGEFBSA-N- Molecular formula
- C6H12O6
- Average molar mass
- 180.16 g/mol
- Monoisotopic mass
- 180.0633881
Names & identifiers
- Preferred name
- Alpha-D-Glucose
- IUPAC
- (2S,3R,4S,5S,6R)-6-(hydroxymethyl)oxane-2,3,4,5-tetrol
- English name
- Dextrose
- Molecular formula
- C6H12O6
- Molecular weight
- 180.16
Names & synonyms
Show more names
Database identifiers
- CAS
492-62-6- PubChem CID
- 79025
- DTXSID
DTXSID30197710- ChEMBL
CHEMBL423707- ChEBI
CHEBI:28102- UNII
- 5J5I9EB41E
- EC Number
- 207-757-8
- Nikkaji
- J44.217H
Properties
Computed structural properties
- XLogP
- -2.6
- Topological polar surface area
- 110 Ų
- Hydrogen bond donors
- 5
- Hydrogen bond acceptors
- 6
- Rotatable bonds
- 1
- Heavy atoms
- 12
- Formal charge
- 0
- Complexity
- 151
Experimental & physicochemical properties
Physical Description
White crystalline powder; Odorless; [Acros Organics MSDS]
Solid
Collision Cross Section
146.2 Ų [M+Na]+ [CCS Type: DT; Method: single field calibrated with Agilent tune mix (Agilent)]
146.6 Ų [M+Na]+ [CCS Type: DT; Method: single field calibrated with ESI Low Concentration Tuning Mix (Agilent)]
146.5 Ų [M+Na]+;147.1 Ų [M+Na]+
Physicochemical properties
- Melting point
- 153 · 153-156 °C(lit.)
- Boiling point
- 232.96 °C · 232.96°C (rough estimate)
- Density
- 1.544 g/cm3 · 1.544g/cm3
- refractive index
- 20 · n20/D 1.362
- storage temp.
- Sealed in dry,Room Temperature
- solubility
- 2 O: · H2O: 1 M at 20 °C, clear, colorless
- form
- solution
- pka
- 12.12 · 12.12±0.70(Predicted)
- color
- White
- PH
- 5 · 5.0-8.0 (25℃)
- Odor
- odorless
- optical activity
- 20 · [α]20/D +52°, c = 10 in H2O
- Water Solubility
- 450.5 g/L · 450.5g/L(25 ºC)
- λmax
- 260 nm · λ: 260 nm Amax: 0.04λ: 280 nm Amax: 0.04
- BRN
- 1281608 · 1281608
- InChI
- 1S/C6H12O6/c7-1-2-3(8)4(9)5(10)6(11)12-2/h2-11H,1H2/t2-,3-,4+,5-,6+/m1/s1
- InChIKey
- WQZGKKKJIJFFOK-DVKNGEFBSA-N
- SMILES
- OC[C@H]1O[C@H](O)[C@H](O)[C@@H](O)[C@@H]1O
- LogP
- -1.88 · -1.880 (est)
- CAS DataBase Reference
- 492 · 492-62-6(CAS DataBase Reference)
- FDA UNII
- 5 J5I9EB41E · 5J5I9EB41E
- UNSPSC Code
- 12352201 · 12352201
- NACRES
- 25 · NA.25
- CAS Number Unlabeled
- 50 · 50-99-7
- Symbol(GHS)
- 7 · GHS07
- Signal word
- Warning
- Hazard statements
- 315 · H315-H319-H335
- Precautionary statements
- 261 · P261-P305+P351+P338
- PPE
- 95 · Eyeshields, Gloves, type N95 (US)
- Hazard Codes
- Xi
- Risk Statements
- 36 · 36/37/38
- Safety Statements
- 26 · 26-36/37/39
- WGK Germany
- 3 · 3
- RTECS
- 6600000 · LZ6600000
- F
- 3 · 3
- HS Code
- 17023000 · 17023000
- Storage Class
- 11 · 11 - Combustible Solids
Safety & regulation
GHS classification
GHS Classification
This chemical does not meet GHS hazard criteria for 98% (48 of 49) of all reports.
Not Classified;Reported as not meeting GHS hazard criteria by 48 of 49 companies (only 2% companies provided GHS information). For more detailed information, please visit ECHA C&L website.
Aggregated GHS information provided per 49 reports by companies from 3 notifications to the ECHA C&L Inventory.;Reported as not meeting GHS hazard criteria per 48 of 49 reports by companies.;There is 1 notification provided by 1 of 49 reports by companies with hazard statement code(s).;Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website.
Hazard information
Regulatory Information
Chemical: .alpha.-D-Glucopyranose
.alpha.-D-Glucopyranose: Does not have an individual approval but may be used under an appropriate group standard
Regulatory information
Regulatory Information
Chemical: .alpha.-D-Glucopyranose
.alpha.-D-Glucopyranose: Does not have an individual approval but may be used under an appropriate group standard
Safety data
- F
- 3
- PPE
- Eyeshields, Gloves, type N95 (US)
- wgk
- 3
- rtecs
- LZ6600000
- hs_code
- 17023000
- risk_code
- 36/37/38
- Signal word
- Warning
- Symbol(GHS)
- GHS07
- hazard_code
- Xi
- safety_code
- 26-36/37/39
- Storage Class
- 11 - Combustible Solids
- Hazard statements
- H315-H319-H335
- Precautionary statements
- P261-P305+P351+P338
Chemistry & industry
Pharmacology
Metabolite Pathways
Fanconi-bickel syndrome;Fructose and mannose metabolism;Fructose intolerance, hereditary;Fructose-1,6-diphosphatase deficiency;Fructosuria;Galactose Metabolism;Galactosemia;Galactosemia II (GALK);Galactosemia III;Glycogen Storage Disease Type 1A (GSD1A) or Von Gierke Disease;Total 28 pathways, visit the HMDB page for details
Uses & manufacturing
Applications
Usesα-D-Glucose is used:As a reducing agent in the preparation superparamagnetic ferrous oxide (Fe3O4) nanoparticles and silver nanocrystals.As an additive for the formation of isoporous polystyrene-block-poly(4-vinylpyridine) (PS-b-P4VP) diblock copolymer membranes.For glycosylation of cell-penetrating poly(disulfide)s (CPDs) with improved solubility to achieve multifunctional cellular uptake.As a precursor in the synthesis of metal/carbon nanohybrids under hydrothermal conditions.
UsesD-(+)-Glucose is a common natural sugar involved in processes such as energy production, glycosylation, and formation of glycans that provide structure to cells. Glucose is involved in a detrimentatl process in cells called glycation. Glucose is used as a supplement for cell culture and in numerous cellular processes and molecular biology applications.
Upstream & downstream products
Upstream raw materials
Downstream products
Suppliers50 total
Additional notes
DefinitionChEBI: D-Glucopyranose having alpha-configuration at the anomeric centre.
Related reactions
Linked notes
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