1-Ethylpiperazine

HCID 79196CAS 5308-25-8
Substructure searchFind similar structures

Basic information

Standard SMILES
CCN1CCNCC1
InChIKey
WGCYRFWNGRMRJA-UHFFFAOYSA-N
Molecular formula
C6H14N2
Average molar mass
114.19 g/mol
Monoisotopic mass
114.11569845

Names & identifiers

Preferred name
1-Ethylpiperazine
IUPAC
1-ethylpiperazine
English name
1-Ethylpiperazine
Molecular formula
C6H14N2
Molecular weight
114.19

Names & synonyms

1-Ethylpiperazine5308-25-8N-EthylpiperazinePiperazine, 1-ethyl-EINECS 226-166-6UNII-6W2BW0V73G6W2BW0V73GNSC-607071-Ethyl-2,5-dihydropiperazineDTXSID8073346EC 226-166-6N-ETHYLPIPERAZINE [USP-RS]
Show more names
NEPRZ1-EthylperazineN-EthylpiperazinETHYLPIPERAZINE-NAKOS BBS-000036101-ethyl-piperazin1-ethvlpiperazineN-Alkylpiperazine
NSC 60707N-ETHYLPIPERAZINE (USP-RS)RefChem:75775DTXCID5041352InChI=1/C6H14N2/c1-2-8-5-3-7-4-6-8/h7H,2-6H2,1HWGCYRFWNGRMRJA-UHFFFAOYSA-NN-ethyl piperazine1-ethyl-piperazine

Database identifiers

CAS
5308-25-8
PubChem CID
79196
DTXSID
DTXSID8073346
UNII
6W2BW0V73G
EC Number
226-166-6
Nikkaji
J208.490B

Properties

Computed structural properties

XLogP
0
Topological polar surface area
15.3 Ų
Hydrogen bond donors
1
Hydrogen bond acceptors
2
Rotatable bonds
1
Heavy atoms
8

Experimental & physicochemical properties

SpringerMaterials PropertiesRefractive index

Physicochemical properties

Melting point
-60 °C · -60 °C
Boiling point
157 °C · 157 °C(lit.)
Density
0.899 g/mL · 0.899 g/mL at 25 °C(lit.)
vapor pressure
2.48 hPa · 2.48hPa at 20℃
refractive index
20 · n20/D 1.469(lit.)
Flash point
110 °F · 110 °F

Safety & regulation

GHS classification

GHS Classification · 4 items

Danger

H226 (100%): Flammable liquid and vapor [Warning Flammable liquids]

P210, P233, P240, P241, P242, P243, P260, P261, P264, P264+P265, P270, P271, P272, P280, P301+P317, P301+P330+P331, P302+P352, P302+P361+P354, P303+P361+P353, P304+P340, P305+P351+P338, P305+P354+P338, P316, P317, P319, P321, P330, P332+P317, P333+P317, P337+P317, P362+P364, P363, P370+P378, P403+P233, P403+P235, P405, and P501 (click each P-code to see the statement)

Aggregated GHS information provided per 275 reports by companies from 12 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

Hazard information

Regulatory Information · 2 items

Status: Active Update: 12-11-2020 https://echa.europa.eu/registration-dossier/-/registered-dossier/31739

1-Ethylpiperazine: Does not have an individual approval but may be used under an appropriate group standard

Hazard Classes and CategoriesFlam. Liq. 3 (100%)

Safety data

F
10-34
PPE
Eyeshields, Gloves, type ABEK (EN14387) respirator filter
wgk
1
rtecs
TM0815500
ridadr
UN 1993 3/PG 3
hs_code
29335995

Chemistry & industry

Applications · 2 items

Uses1-Ethylpiperazine is used in the synthesis of 2-(2-methoxy-5-((4-methylpiperazin-1-yl)sulfonyl)phenyl)-1H-benzo[d]imidazole hydrochloride and 2-(5-((4-ethylpiperazin-1-yl)sulfonyl)-2-methoxyphenyl)-1H-benzo[d]imidazole hydrochloride. It is also employed as an intermediate in veterinary medicine, especially in the production of ciproflmoxacin ethyl. Further, it serves as a precursor to prepare dyes.

Uses1-Ethylpiperazine may be used in the preparation of 2-(2-methoxy-5-((4-methylpiperazin-1-yl)sulfonyl)phenyl)-1H-benzo[d]imidazole hydrochloride and 2-(5-((4-ethylpiperazin-1-yl)sulfonyl)-2-methoxyphenyl)-1H-benzo[d]imidazole hydrochloride.

Upstream & downstream products

Suppliers50 total

国药集团化学试剂有限公司86-21-63210123 · [email protected]
梯希爱(上海)化成工业发展有限公司021-67121386 · [email protected]
衢州润东化工有限公司0570-8789886 18892685668 · [email protected]
上海阿拉丁生化科技股份有限公司400-6206333 13167063860 · [email protected]
爱斯特（成都）生物制药股份有限公司+86-28-85122536 85324413 · [email protected]

Related reactions

484 records
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Linked notes

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