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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 7936Generated: October 23, 2026

2,4-Dimethylpyridine

LUTIDINE · 2,4-DIMETHYLPYRIDINE · 24L · 2,4-Lutidene · 2,4-LUTIDINE · 2,4-Lutidine>2,4-Lutidine 99% · 2,4-LUTIDINE 98+% · 2,4-dimethyl-pyridin

https://huagongshe.com/en/chemical/7936

2,4-Dimethylpyridine molecular structure

Identifiers & Physical Properties

CAS No.108-47-4
Molecular formulaC7H9N
Average molar mass107.15 g/mol
Monoisotopic mass107.07349929 g/mol
SMILESCc1ccnc(C)c1
InChIKeyJYYNAJVZFGKDEQ-UHFFFAOYSA-N
PubChem CID7936
ChEMBLCHEMBL5286019
ChEBICHEBI:192115
EC No.203-586-8
DTXSIDDTXSID2051556

Chemical & Physical Properties

XLogP1.6
Topological polar surface area12.9
Hydrogen bond donors0
Hydrogen bond acceptors1
Rotatable bonds0
Heavy atoms8
Formal charge0
Complexity70.8
Chemical classesNitrogen Compounds -> Pyridines
SpringerMaterials Properties15N nuclear magnetic resonance spectrum
FragrancesFragrance Ingredient (2,4-Dimethylpyridine) -> IFRA transparency List
LogP (partition coefficient)1.58
Food additivesFLAVORING AGENT OR ADJUVANT -> FDA Substance added to food
Density0.929 - 0.935 (20º)0.927 g/mL at 25 °C (lit.)
Flavoring agentsEU Flavoring substances
Solubility350 mg/mL at 25 °CSlightly soluble in waterSoluble (in ethanol)350g/l15 g/100 mL (20 ºC)
Boiling point158-159º145.7 °C @760 [mm Hg]159 °C (lit.)
Melting point-64 °C-6.1 °C-60 °C (lit.)
Vapor pressure3.17 [mmHg]5.65 [mm Hg] @25 °C3.28hPa at 25℃
Food Contact SubstancesFCS -> FDA Cumulative Estimated Daily Intake (CEDI)FCS -> FDA Inventory of Food Contact Substances Listed in 21 CFR
FEMA4389 | 2,4-DIMETHYLPYRIDINE
Refractive indexn20/D 1.499(lit.)
FLAVIS Number14.104 | 2,4-Dimethylpyridine
Flash point99 °F
Storage conditionsFlammables area
Physical stateLiquid
pKa (acidity coefficient)6.99(at 25℃)
ColorColorless to Light yellow to Light orange
Odorat 0.01 % in dipropylene glycol. smoky phenolic
Odor typesmoky
Specific heat capacityCp(liquid): 1.72 J/(g·K), at 25℃
SensitivityHygroscopic
JECFA Number2151
BRN1506
Henry's law constant9.9×10-1 mol/(m3Pa) at 25℃, Hawthorne et al. (1985)
Dielectric constant9.5999999999999996
Major applicationsflavors and fragrances
Cosmetics Ingredients FunctionsPERFUMING
InChI1S/C7H9N/c1-6-3-4-8-7(2)5-6/h3-5H,1-2H3
InChIKeyJYYNAJVZFGKDEQ-UHFFFAOYSA-N
SMILESCc1ccnc(C)c1
LogP (partition coefficient)1.9
CAS DataBase Reference108-47-4(CAS DataBase Reference)
Substances Added to Food (formerly EAFUS)2,4-DIMETHYLPYRIDINE
FDA 21 CFR177.1520
EWG's Food Scores1
FDA UNII83903UJ0WW
NIST Chemistry ReferencePyridine, 2,4-dimethyl-(108-47-4)
EPA Substance Registry System2,4-Dimethylpyridine (108-47-4)
UNSPSC Code85151701
NACRESNA.22
GHS pictogramGHS02,GHS06
Signal wordDanger
GHS hazard statementsH301-H315-H319-H226
GHS precautionary statementsP501-P270-P240-P210-P233-P243-P241-P242-P264-P280-P370+P378-P337+P313-P305+P351+P338-P362+P364-P303+P361+P353-P332+P313-P301+P310+P330-P403+P235-P405
Target organsRespiratory system
Hazard symbolsT,F,Xi
Risk statements (R)10-23/24/25-36/37/38-25-20/21-20/21/22
Safety statements (S)16-26-36/37/39-45
UN transport numberUN 1992 3/PG 3
Water hazard class (WGK)3
RTECS numberOK9400000
F8
TSCA inventory statusTSCA listed
Hazard class3Acute Tox. 3 DermalAcute Tox. 3 InhalationAcute Tox. 3 OralEye Irrit. 2Flam. Liq. 3Skin Irrit. 2STOT SE 3
Packing groupIII
Customs code29333999
Storage class3 - Flammable liquids
REACH registrationsActive
Limited quantities5.0 L (1.3 gallons) (liquid)
Excepted quantitiesMax Inner Pack (30g or 30ml) and Max Outer Pack (1Kg or 1L)

Safety & Regulations

GHS classificationWarningH226 (11.3%): Flammable liquid and vapor [Warning Flammable liquids]P210, P233, P240, P241, P242, P243, P261, P264, P270, P271, P280, P301+P317, P302+P352, P303+P361+P353, P304+P340, P317, P321, P330, P362+P364, P370+P378, P403+P235, and P501 (click each P-code to see the statement)Aggregated GHS information provided per 1450 reports by companies from 12 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.
Regulatory informationChemical: Pyridine, 2,4-dimethyl-Commission Regulation (EC) No 1565/2000 (Repealed by Com. Implementing Reg. (EU) No 872/2012)Status: Active Update: 17-12-2020 https://echa.europa.eu/registration-dossier/-/registered-dossier/320272,4-Dimethylpyridine: Does not have an individual approval but may be used under an appropriate group standard
Hazards summaryA skin, respiratory tract, and strong eye irritantHighly toxic by inhalationToxic by ingestion and skin absorption[Aldrich MSDS] See Pyridine.
Hazard Classes and CategoriesFlam. Liq. 3 (11.3%)
Protective Action Criteria (PAC)0.60 [mg/m3]6.6 [mg/m3]40 [mg/m3]
F8
Water hazard class (WGK)3
TSCA inventory statusTSCA listed
RTECS numberOK9400000
UN transport numberUN 1992 3/PG 3
Customs code29333999
Risk statements (R)10-23/24/25-36/37/38-25-20/21-20/21/22
Signal wordDanger
GHS pictogramGHS02,GHS06
Hazard symbolsT,F,Xi
Safety statements (S)16-26-36/37/39-45
Hazard class3Acute Tox. 3 DermalAcute Tox. 3 InhalationAcute Tox. 3 OralEye Irrit. 2Flam. Liq. 3Skin Irrit. 2STOT SE 3
Storage class3 - Flammable liquids
Packing groupIII
Target organsRespiratory system
GHS hazard statementsH301-H315-H319-H226
Limited quantities5.0 L (1.3 gallons) (liquid)
Excepted quantitiesMax Inner Pack (30g or 30ml) and Max Outer Pack (1Kg or 1L)
REACH registrationsActive
GHS precautionary statementsP501-P270-P240-P210-P233-P243-P241-P242-P264-P280-P370+P378-P337+P313-P305+P351+P338-P362+P364-P303+P361+P353-P332+P313-P301+P310+P330-P403+P235-P405

Applications & Uses

Uses

2,4-Lutidine, can be used as a building block in the synthesis of various chemical compounds. It is also used tobacco and aroma component.

Preparation & Synthesis

Preparation

2,4-Lutidine is produced industrially by extraction from coal tars.