2-Amino-4-methylpyrimidine (HCID 7939)

Overview

2-Amino-4-methylpyrimidine is an aminopyrimidine.

Names & identifiers

Preferred name: 2-Amino-4-methylpyrimidine
IUPAC: 4-methylpyrimidin-2-amine
English name: 2-Amino-4-methylpyrimidine
Molecular formula: C5H7N3
Molecular weight: 109.13

Names & synonyms

2-AMINO-4-METHYLPYRIMIDINE108-52-12-Pyrimidinamine, 4-methyl-6-Methyl-2-pyrimidinamine4-Methylpyrimidin-2-ylamineZEQ6ZS0OOCNSC 1939EINECS 203-591-5BRN 0108506AI3-08091NSC-19395-25-10-00160 (Beilstein Handbook Reference)

Show more names

TIMTEC-BB SBB004343AMINO-4-METHYLPYRIMIDINE2-amino-4-methyl-pyrimidin2-AMINO-4-METHYL-1,3-DIAZINE

RefChem:4643472-Pyrimidinamine, 4-methyl-(9CI)InChI=1/C5H7N3/c1-4-2-3-7-5(6)8-4/h2-3H,1H3,(H2,6,7,84-methylpyrimidin-2-amine4-Methyl-2-pyrimidinaminePyrimidine, 2-amino-4-methyl-MFCD000061012-AMINO-4-METHYL-PYRIMIDINE

Database identifiers

CAS: 108-52-1
PubChem CID: 7939
DTXSID: DTXSID90148349
ChEBI: CHEBI:170014
UNII: ZEQ6ZS0OOC
EC Number: 203-591-5
Nikkaji: J79.446E

Properties

Computed structural properties

XLogP: 0.3
Topological polar surface area: 51.8 Å²
Hydrogen bond donors: 1
Hydrogen bond acceptors: 3
Rotatable bonds: 0
Heavy atoms: 8
Formal charge: 0
Complexity: 74.1

Experimental & physicochemical properties

SpringerMaterials PropertiesDiamagnetic susceptibility

Physicochemical properties

Melting point: 158 · 158-160 °C(lit.)
Boiling point: 194.6 °C · 194.6°C (rough estimate)
Density: 1 g/cm3 · 1 g/cm3
refractive index: 1.534 · 1.5340 (estimate)
storage temp.: Keep in dark place,Inert atmosphere,Room temperature
solubility: DMSO (Slightly), Methanol (Slightly)
form: Crystalline Powder
pka: 1 · pK1: 4.11(+1) (20°C)
color: Off-white to light brown
BRN: 108506 · 108506
CAS DataBase Reference: 108 · 108-52-1(CAS DataBase Reference)
EWG's Food Scores: 1 · 1
FDA UNII: 6 ZS0OOC · ZEQ6ZS0OOC
NIST Chemistry Reference: 2 · 2-Amino-4-methylpyrimidine(108-52-1)
Symbol(GHS): 7 · GHS07
Signal word: Warning
Hazard statements: 335 · H335-H315-H319
Precautionary statements: 264 · P264-P280-P302+P352+P332+P313+P362+P364-P305+P351+P338+P337+P313-P305+P351+P338-P261-P280a-P304+P340-P405-P501a
Hazard Codes: Xi
Risk Statements: 36 · 36/37/38
Safety Statements: 26 · 26-36
WGK Germany: 3 · 3
RTECS: 6485000 · UV6485000
Hazard Note: Irritant
HS Code: 29335990 · 29335990

Safety & regulation

GHS classification

GHS Classification · 4 items

Warning

H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]

P261, P264, P264+P265, P271, P280, P302+P352, P304+P340, P305+P351+P338, P319, P321, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501 (click each P-code to see the statement)

Aggregated GHS information provided per 47 reports by companies from 6 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

Hazard information

Regulatory Information2-Pyrimidinamine, 4-methyl-: Does not have an individual approval but may be used as a component in a product covered by a group standard. It is not approved for use as a chemical in its own right.

Hazard Classes and CategoriesSkin Irrit. 2 (100%)

Safety data

wgk: 3
rtecs: UV6485000
hs_code: 29335990
risk_code: 36/37/38
Signal word: Warning
Symbol(GHS): GHS07
hazard_code: Xi
hazard_note: Irritant
safety_code: 26-36
Hazard statements: H335-H315-H319
Precautionary statements: P264-P280-P302+P352+P332+P313+P362+P364-P305+P351+P338+P337+P313-P305+P351+P338-P261-P280a-P304+P340-P405-P501a

Chemistry & industry

Applications · 1 item

Uses2-Amino-4-methylpyrimidine is a compound involved in a study about carbonylation as a key reaction in anaerobic acetone activation by Desulfococcus biacutus. 2-Amino-4-methylpyrimidine is formed as the product of a reaction between acetoacetaldehyde and guanidine.