Basic information
- CAS
5577-13-9- Standard SMILES
CCOC(=O)NS(=O)(=O)c1ccc(C)cc1- InChIKey
DFWQXANLGSXMKF-UHFFFAOYSA-N- Molecular formula
- C10H13NO4S
- Average molar mass
- 243.28 g/mol
- Monoisotopic mass
- 243.05652907
Names & identifiers
- Preferred name
- Ethyl ((4-methylphenyl)sulphonyl)carbamate
- IUPAC
- ethyl N-(4-methylphenyl)sulfonylcarbamate
- English name
- Ethyl N-(4-methylphenyl)sulfonylcarbamate
- Molecular formula
- C10H13NO4S
- Molecular weight
- 243.28
Names & synonyms
Ethyl ((4-methylphenyl)sulphonyl)carbamateETHYL [(4-METHYLPHENYL)SULPHONYL]CARBAMATEEINECS 226-952-9EC 226-952-9Ethyl N-[(4-methylphenyl)sulfonyl]carbamateEthyl N-((4-methylphenyl)sulfonyl)carbamateRefChem:592863226-952-9Ethyl tosylcarbamate5577-13-9TosylurethaneGliclazide EP Impurity C
Show more names
Tosylcarbamic acid ethyl esterEthyl [(4-Methylphenyl)sulphonyl]caEthyl [(4-methylphenyl)sulfonyl]-carbamate
ethyl N-(4-methylphenyl)sulfonylcarbamateN-tosylurethaneGliclazide Impurity Cethyl N-(4-methylbenzenesulfonyl)carbamateMFCD00797861Ethyl p-tosylcarbamateCarbamic acid, [(4-methylphenyl)sulfonyl]-, ethyl esterEthyl (p-tolylsulfonyl)carbamate
Database identifiers
- CAS
5577-13-9- PubChem CID
- 79683
- DTXSID
DTXSID80971143- UNII
- P83946FTE5
- EC Number
- 226-952-9
- Nikkaji
- J103.095G
Properties
Computed structural properties
- XLogP
- 1.9
- Topological polar surface area
- 80.9 Ų
- Hydrogen bond donors
- 1
- Hydrogen bond acceptors
- 4
- Rotatable bonds
- 4
- Heavy atoms
- 16
- Formal charge
- 0
- Complexity
- 325
Physicochemical properties
- Melting point
- 82 · 82-84oC
- Boiling point
- 272 ℃ · 272℃ at 100.8-101kPa
- Density
- 1.38 at · 1.38 at 20℃
- vapor pressure
- 1.8 · 1.8-7.9Pa at 20-25℃
- storage temp.
- Sealed in dry,Room Temperature
- solubility
- Chloroform (Slightly), Ethyl Acetate (Slightly)
- form
- Solid
- color
- White
- LogP
- 0.73 · 0.73-1.7 at 23℃ and pH2-7
- Surface tension
- 63.8 mN/m · 63.8mN/m at 1g/L and 20℃
- Symbol(GHS)
- 7 · GHS07
- Signal word
- Warning
- Hazard statements
- 315 · H315-H319
- Precautionary statements
- 264 · P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313
- REACH Registrations
- Active
Safety & regulation
Safety information is for reference only and does not replace the supplier’s Safety Data Sheet (SDS), applicable regulations, or professional assessment.
GHS classification
GHS Classification
Warning
H302 (40%): Harmful if swallowed [Warning Acute toxicity, oral]
P261, P264, P264+P265, P270, P271, P273, P280, P301+P317, P302+P352, P304+P340, P305+P351+P338, P319, P321, P330, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501 (click each P-code to see the statement)
Aggregated GHS information provided per 5 reports by companies from 3 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.
Hazard information
Regulatory InformationREACH registered substance: Ethyl [(4-methylphenyl)sulphonyl]carbamate (EC: 226-952-9)
Hazard Classes and CategoriesSkin Irrit. 2 (20%)
Safety data
- Signal word
- Warning
- Symbol(GHS)
- GHS07
- Hazard statements
- H315-H319
- REACH Registrations
- Active
- Precautionary statements
- P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313
Chemistry & industry
Applications
UsesTosylurethane (Gliclazide EP Impurity C) is an intermediate in the synthesis of Gliclazide (G409877), a sulfonylurea hypoglycemic agent. Used as an antidiabetic.
Upstream & downstream products
Upstream raw materials
Suppliers76 total
北京福源坊科技有限公司010-57903446 15869909019 · [email protected]
Career Henan Chemica Co+86-0371-86658258 +86-13203830695 · [email protected]
艾吉析科技（上海）有限公司17717235263 · [email protected]
上海麦克林生化科技股份有限公司021-50706066 15221275939 · [email protected]
广州隽沐生物科技股份有限公司020-36607679; 13502246435 · [email protected]
上海毕得医药科技股份有限公司400-1647117 13681763483 · [email protected]
南京望知星医药科技有限公司18569809817 · [email protected]
Dayang Chem (Hangzhou) Co.,Ltd.+86-0571-88938639 17705817739 · [email protected]
广州隽唐科技有限公司020-36607679 13502246435 · [email protected]
Related reactions
0 records
No reaction records under the current filter.
Compound notes
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