CAS 5762-56-1 N,N,N',N',N'',N''-Hexamethylmethanetriamine (HCID 79831)

Names & identifiers

Preferred name: N,N,N',N',N'',N''-Hexamethylmethanetriamine
IUPAC: N,N,N',N',N",N"-hexamethylmethanetriamine
English name: Tris(dimethylamino)methane
Molecular formula: C7H19N3
Molecular weight: 145.25

Names & synonyms

5762-56-1N,N,N',N',N'',N''-HexamethylmethanetriamineEINECS 227-284-0DTXSID20206284RefChem:822031DTXCID20128775227-284-0Tris(dimethylamino)methane[bis(dimethylamino)methyl]dimethylamineN,N,N',N',N",N"-hexamethylmethanetriamineMFCD00008322N,N,N,N,N,n-Hexamethylmethanetriamine

Show more names

Tris(N,N-dimethylamino)methaneTris(dimethylamino)methane,85%Tris(dimethylamino)methane 97%Tris(dimethylamino) methane, 96%+Tris(diMethylaMino)Methane, 85% 5GRN,N',N''-Methylidynetris(dimethylamine)

Methanetriamine, N,N,N',N',N'',N''-hexamethyl-8T74D2Q5VHtrisdimethylaminomethanetris-dimethylaminomethanetris (dimethylamino)methanetris(dimethylamino) methanetris(dimethylamino)-methanetris-(dimethylamino)methane

Database identifiers

CAS: 5762-56-1
PubChem CID: 79831
DTXSID: DTXSID20206284
ChEMBL: CHEMBL3301703
UNII: 8T74D2Q5VH
EC Number: 227-284-0
Nikkaji: J209.013I

Properties

Computed structural properties

XLogP: 0.6
Topological polar surface area: 9.7 Å²
Hydrogen bond donors: 0
Hydrogen bond acceptors: 3
Rotatable bonds: 3
Heavy atoms: 10
Formal charge: 0
Complexity: 69.8

Physicochemical properties

Boiling point: 42 · 42-43 °C/12 mmHg (lit.)
Density: 0.838 g/mL · 0.838 g/mL at 20 °C (lit.)
refractive index: 20 · n20/D 1.436(lit.)
Flash point: 4 °F · 4 °F
storage temp.: 2 · 2-8°C
form: Liquid
pka: 6.5 · 6.50±0.38(Predicted)
color: Clear colorless to slightly yellow
BRN: 1901162 · 1901162
InChI: InChI=1S/C7H19N3/c1-8(2)7(9(3)4)10(5)6/h7H,1-6H3
InChIKey: MUMVIYLVHVCYGI-UHFFFAOYSA-N
SMILES: C(N(C)C)(N(C)C)N(C)C
FDA UNII: 8 T74D2Q5VH · 8T74D2Q5VH
UNSPSC Code: 12352100 · 12352100
NACRES: 22 · NA.22
Symbol(GHS): 2 · GHS02,GHS05
Signal word: Danger
Hazard statements: 225 · H225-H314
Precautionary statements: 210 · P210-P233-P240-P280-P303+P361+P353-P305+P351+P338
PPE: Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter
Hazard Codes: F,C
Risk Statements: 11 · 11-34
Safety Statements: 16 · 16-26-36/37/39-45
RIDADR: 2733 · UN 2733 3/PG 2
WGK Germany: 3 · 3
F: 3 · 3-8-10-21
Hazard Note: Corrosive/Highly Flammable
HazardClass: 3.1 · 3.1
PackingGroup: II
HS Code: 29212900 · 29212900
Storage Class: 3 · 3 - Flammable liquids
Hazard Classifications: 2 Skin · Flam. Liq. 2Skin Corr. 1B

Safety & regulation

GHS classification

GHS Classification · 4 items

Danger

H225 (100%): Highly Flammable liquid and vapor [Danger Flammable liquids]

P210, P233, P240, P241, P242, P243, P260, P264, P280, P301+P330+P331, P302+P361+P354, P303+P361+P353, P304+P340, P305+P354+P338, P316, P321, P363, P370+P378, P403+P235, P405, and P501 (click each P-code to see the statement)

Aggregated GHS information provided per 42 reports by companies from 2 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

Hazard information

Hazard Classes and CategoriesFlam. Liq. 2 (100%)

Safety data

F: 3-8-10-21
PPE: Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter
wgk: 3
ridadr: UN 2733 3/PG 2
hs_code: 29212900
risk_code: 11-34
Signal word: Danger
Symbol(GHS): GHS02,GHS05
hazard_code: F,C
hazard_note: Corrosive/Highly Flammable
safety_code: 16-26-36/37/39-45
hazard_class: 3.1
Storage Class: 3 - Flammable liquids
packing_group: II
Hazard statements: H225-H314
Hazard Classifications: Flam. Liq. 2Skin Corr. 1B
Precautionary statements: P210-P233-P240-P280-P303+P361+P353-P305+P351+P338

Chemistry & industry

Applications · 4 items

UsesReagent for the introduction of the dimethylaminoethylidene group.1 General review;2 RO polymerization of lactide.3

UsesN,N,N'',N'',N'''',N''''-Hexamethylmethanetriamine, can be used in the synthesis of the phosphoramidite derivative of the new nucleoside analog. It can also be used as reagent for the introduction of the dimethylaminoethylidene group.

UsesTris(dimethylamino)methane was used:to prepare the phosphoramidite derivative of the new nucleoside analogas reagent for the introduction of the dimethylaminoethylidene group in ring-opening (RO) polymerization of lactide

General DescriptionNMR spectra and their temperature-dependence has been reported for tris(dimethylamino)methane. Tris(dimethylamino)methane reacts with crowded α-(o-nitrophenyl) ketone to yield tetrahydroquinoline derivative.