2-Hydrazinoethanol (HCID 8017)

Overview

2-hydrazinoethanol is a member of hydrazines. It has a role as a herbicide. It is functionally related to an ethanol.

Names & identifiers

Preferred name: 2-Hydrazinoethanol
IUPAC: 2-hydrazinylethanol
English name: 2-Hydroxyethylhydrazine
Molecular formula: C2H8N2O
Molecular weight: 76.1

Names & synonyms

2-Hydrazinoethanol2-Hydroxyethylhydrazine2-hydrazinylethanolOmafloraEthanolhydrazine(2-Hydroxyethyl)hydrazineHydrazineethanol2-Hydrazinoethyl alcoholETHANOL, 2-HYDRAZINO-2-HydrazineethanolN-(2-Hydroxyethyl)hydrazine1-(2-Hydroxyethyl)hydrazine

Show more names

BOHHEH2HYDRAZINOETHANOL

BrombloomHydroxyethylhydrazineEthanol, 2-hydrazinyl-Ethanol, 2-hydrazinoCaswell No. 488Abeta-Hydroxyethyl hydrazineCCRIS 1077NSC 189820

Database identifiers

CAS: 109-84-2
PubChem CID: 8017
DTXSID: DTXSID1020728
ChEMBL: CHEMBL3183346
ChEBI: CHEBI:50098
UNII: 8T2Z8Z231F
EC Number: 203-711-6
Nikkaji: J25.002C

Properties

Computed structural properties

XLogP: -1.6
Topological polar surface area: 58.3 Å²
Hydrogen bond donors: 3
Hydrogen bond acceptors: 3
Rotatable bonds: 2
Heavy atoms: 5
Formal charge: 0
Complexity: 17.1

Physicochemical properties

Melting point: 70 °C · −70 °C(lit.)
Boiling point: 155 · 155-160 °C32 mm Hg(lit.)
Density: 1.123 g/mL · 1.123 g/mL at 25 °C(lit.)
refractive index: 20 · n20/D 1.493(lit.)
Flash point: 165 °F · 165 °F
storage temp.: -20 °C · Keep in dark place,Inert atmosphere,Store in freezer, under -20°C
solubility: soluble in DMSO, Methanol
form: Liquid
pka: 14.79 · 14.79±0.10(Predicted)
color: Colorless to Almost colorless
Water Solubility: Soluble in water, alcohols and glycols.
Merck: 13 · 13,4794
BRN: 1731669 · 1731669
InChI: 1S/C2H8N2O/c3-4-1-2-5/h4-5H,1-3H2
InChIKey: GBHCABUWWQUMAJ-UHFFFAOYSA-N
SMILES: NNCCO
CAS DataBase Reference: 109 · 109-84-2(CAS DataBase Reference)
EWG's Food Scores: 1 · 1
FDA UNII: 8 T2Z8Z231F · 8T2Z8Z231F
NIST Chemistry Reference: 2 · 2-Hydroxyethylhydrazine(109-84-2)
EPA Substance Registry System: 2 · 2-Hydroxyethylhydrazine (109-84-2)
UNSPSC Code: 12352100 · 12352100
NACRES: 22 · NA.22
Symbol(GHS): 6 · GHS06,GHS08
Signal word: Danger
Hazard statements: 301 · H301+H311+H331-H315-H319-H335-H351
Precautionary statements: 201 · P201-P280-P301+P310+P330-P302+P352+P312-P304+P340+P311-P305+P351+P338
target organs: Respiratory system
PPE: Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter
Hazard Codes: T
Risk Statements: 23 · 23/24/25-36/37/38-40-25
Safety Statements: 23 · 23-26-36/37/39-45-60-20
RIDADR: 2810 · UN 2810 6.1/PG 3
WGK Germany: 3 · 3
RTECS: 2800000 · KL2800000
Hazard Note: Toxic
TSCA: TSCA listed
HazardClass: 6.1 · 6.1
PackingGroup: II
HS Code: 29280000 · 29280000
Storage Class: 6.1 C · 6.1C - Combustible acute toxic Cat.3toxic compounds or compounds which causing chronic effects
Hazard Classifications: 3 DermalAcute · Acute Tox. 3 DermalAcute Tox. 3 InhalationAcute Tox. 3 OralCarc. 2Eye Irrit. 2Skin Irrit. 2STOT SE 3
Limited Quantities: 5 L · 5.0 L (1.3 gallons) (liquid) or 5.0 kg (11 lbs) (solid)
Excepted Quantities: Max Inner Pack (30g or 30ml) and Max Outer Pack (1Kg or 1L)

Safety & regulation

GHS classification

GHS Classification · 6 items

Danger

H301 (97.9%): Toxic if swallowed [Danger Acute toxicity, oral]

P203, P261, P262, P264, P264+P265, P270, P271, P280, P301+P316, P302+P352, P304+P340, P305+P351+P338, P316, P318, P319, P321, P330, P332+P317, P337+P317, P361+P364, P362+P364, P403+P233, P405, and P501 (click each P-code to see the statement)

Aggregated GHS information provided per 47 reports by companies from 7 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

Warning

H227: Combustible liquid [Warning Flammable liquids]

Hazard information

Regulatory InformationEthanol, 2-hydrazino-: Does not have an individual approval but may be used under an appropriate group standard

Hazard Classes and Categories · 3 items

Acute Tox. 3 (97.9%)

Acute toxicity (Oral) - Category 3

Flammable liquids - Category 4

Safety data

PPE: Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter
wgk: 3
tsca: TSCA listed
rtecs: KL2800000
ridadr: UN 2810 6.1/PG 3
hs_code: 29280000
risk_code: 23/24/25-36/37/38-40-25
Signal word: Danger
Symbol(GHS): GHS06,GHS08
hazard_code: T
hazard_note: Toxic
safety_code: 23-26-36/37/39-45-60-20
hazard_class: 6.1
Storage Class: 6.1C - Combustible acute toxic Cat.3toxic compounds or compounds which causing chronic effects
packing_group: II
target organs: Respiratory system
Hazard statements: H301+H311+H331-H315-H319-H335-H351
Limited Quantities: 5.0 L (1.3 gallons) (liquid) or 5.0 kg (11 lbs) (solid)
Excepted Quantities: Max Inner Pack (30g or 30ml) and Max Outer Pack (1Kg or 1L)
Hazard Classifications: Acute Tox. 3 DermalAcute Tox. 3 InhalationAcute Tox. 3 OralCarc. 2Eye Irrit. 2Skin Irrit. 2STOT SE 3
Precautionary statements: P201-P280-P301+P310+P330-P302+P352+P312-P304+P340+P311-P305+P351+P338

Chemistry & industry

Uses & manufacturing

General Manufacturing InformationEthanol, 2-hydrazinyl-: ACTIVE

Applications · 4 items

Description2-Hydroxyethylhydrazine (HEH) is the primary decomposition product of the high-energy ionic liquid 2-hydroxyethylhydrazinium nitrate (HEHN). As a hydrazine fuel, HEHN is the most widely used liquid monocomponent propellant in the aerospace sector. while HEH is a key target for investigating the reaction mechanism of HEHN.

Uses(2-Hydroxyethyl)hydrazine is used as a plant growth regulant, a component in jet fuels, intermediate for organic synthesis especially heterocycles used in agrochemicals, pharmaceuticals, stabilizers and polymerizations, Chain extender for urethane formulations, corrosion inhibitor.

Uses2-Hydroxyethylhydrazine is used as an intermediate, plant growth regulator, flowering inducer for pineapples.

General Description2-Hydroxyethylhydrazine reacts with β-diketones having strong electron-withdrawing substituents to yield 5-hydroxy-4,5-dihydropyrazoles.

Preparation methods · 1 item

Preparation2-Hydroxyethylhydrazine is prepared by heating about 2 to 17 parts of hydrazine hydrate dissolved in water to about 30℃ to about 100℃. in a closed system. Then, 1 part of ethylene oxide is gradually added to the hydrazine hydrate, and the temperature of the reaction mixture is maintained in the range of about 30℃ to 70℃ during the addition.