Basic information
- CAS
26761-84-2- Standard SMILES
O=C1OC2(c3ccc(O)cc3Oc3cc(O)ccc32)c2c(Cl)c(Cl)c(Cl)c(Cl)c21- InChIKey
QCPFFGGFHNZBEP-UHFFFAOYSA-N- Molecular formula
- C20H8Cl4O5
- Average molar mass
- 470.1 g/mol
- Monoisotopic mass
- 467.912584
Names & identifiers
- Preferred name
- Tetrachlorofluorescein
- IUPAC
- 4,5,6,7-tetrachloro-3',6'-dihydroxyspiro[2-benzofuran-3,9'-xanthene]-1-one
- English name
- 3,4,5,6-TETRACHLOROFLUORESCEIN
- Molecular formula
- C20H8Cl4O5
- Molecular weight
- 470.09
Names & synonyms
Tetrachlorofluorescein6262-21-13,4,5,6-Tetrachlorofluorescein4,5,6,7-TetrachlorofluoresceinFluorescein, tetrachloro-O73WZT10BYEINECS 228-413-3Fluorescein, 4,5,6,7-tetrachloro-Spiro[isobenzofuran-1(3H),9'-[9H]xanthen]-3-one, 4,5,6,7-tetrachloro-3',6'-dihydroxy-DTXSID4038895Spiro(isobenzofuran-1(3H),9'-(9H)xanthen)-3-one, 4,5,6,7-tetrachloro-3',6'-dihydroxy-NSC 726280
Show more names
Tetrachlorofluoescein3,4,5,6-Tetrchlorofluorescein2-(1,2,7,8-tetrachloro-3,6-dihydroxy-9H-xanthen-9-yl)benzoic acid4,5,6,7-Tetrachloro-3',6'-dihydroxy-3H-spiro[isobenzofuran-1,9'-xanthen]-3-one4,5,6,7-tetrachloro-3',6'-dihydroxyspiro[isobenzofuran-1(3H),9'-[9H]xanthene]-3-one9’-(9H)xanthen)-3-one,4,5,6,7-tetrachloro-3’,6’-dihydroxy-Spiro(isobenzofuran-1(3H)
NSC-12239226761-84-2FLUORESCEIN, 3,4,5,6-TETRACHLORO-3',4',5',6'-TETRACHLOROFLUORESCEINBENZOIC ACID, 2,3,4,5-TETRACHLORO-6-(6-HYDROXY-3-OXO-3H-XANTHEN-9-YL)-Spiro(isobenzofuran-1(3H),9'-(9H)xanthen)-3-one, tetrachloro-3',6'-dihydroxy-RefChem:896814DTXCID2018895
Properties
Computed structural properties
- XLogP
- 5.9
- Topological polar surface area
- 76 Ų
- Hydrogen bond donors
- 2
- Hydrogen bond acceptors
- 5
- Rotatable bonds
- 0
- Heavy atoms
- 29
- Formal charge
- 0
- Complexity
- 653
Experimental & physicochemical properties
Endocrine DisruptorsPotential endocrine disrupting compound
Physicochemical properties
- Melting point
- 304 ℃ · 304℃
- Boiling point
- 752.3 · 752.3±60.0 °C(Predicted)
- Density
- 1.87 · 1.87±0.1 g/cm3(Predicted)
- form
- powder to crystal
- pka
- 9.18 · 9.18±0.20(Predicted)
- color
- Light yellow to Amber to Dark green
- CAS DataBase Reference
- 6262 · 6262-21-1(CAS DataBase Reference)
- FDA UNII
- 73 WZT10BY · O73WZT10BY
- EPA Substance Registry System
- -1 · Spiro[isobenzofuran-1(3H),9'-[9H]xanthen]-3-one, 4,5,6,7-tetrachloro-3',6'-dihydroxy- (6262-21-1)
- WGK Germany
- 3 · 3
- TSCA
- TSCA listed
- HS Code
- 29329990 · 29329990
Safety & regulation
Safety information is for reference only and does not replace the supplier’s Safety Data Sheet (SDS), applicable regulations, or professional assessment.
Safety data
- wgk
- 3
- tsca
- TSCA listed
- hs_code
- 29329990
Chemistry & industry
Uses & manufacturing
General Manufacturing InformationSpiro[isobenzofuran-1(3H),9'-[9H]xanthen]-3-one, 4,5,6,7-tetrachloro-3',6'-dihydroxy-: ACTIVE
Applications
Description3,4,5,6-Tetrachlorofluorescein is a reactive and monomeric dye that is used in analytical chemistry as a diagnostic agent. It reacts with proteins or peptides to form fluorescent complexes. 3,4,5,6-Tetrachlorofluorescein has been shown to bind to erythrocyte membrane proteins and is excreted in urine. This dye can be used for the detection of protease activity in human serum. 3,4,5,6-Tetrachlorofluorescein has also been used as an innovative pharmaceutical preparation for the treatment of chronic venous ulcers.
Upstream & downstream products
Downstream products
Suppliers49 total
梯希爱(上海)化成工业发展有限公司021-67121386 · [email protected]
合肥曼奇诺生物医药技术有限公司19719236623 · [email protected]
陕西缔都新材料有限公司029-63373950 17392216152 · [email protected]
上海仲因实业有限公司2537653158 16621191650 · [email protected]
Dayang Chem (Hangzhou) Co.,Ltd.+86-0571-88938639 17705817739 · [email protected]
Shenyang Simchoice Chemical Co.,Ltd
Related reactions
0 records
No reaction records under the current filter.
Compound notes
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