Phosphine, cyclohexyldiphenyl- (HCID 80756)

Names & identifiers

Preferred name: Phosphine, cyclohexyldiphenyl-
IUPAC: cyclohexyl(diphenyl)phosphane
English name: Cyclohexyldiphenylphosphine
Molecular formula: C18H21P
Molecular weight: 268.33

Names & synonyms

Cyclohexyldiphenylphosphine6372-42-5Phosphine, cyclohexyldiphenyl-DiphenylcyclohexylphosphineEINECS 228-904-2DTXSID6074671RefChem:861957DTXCID4044086228-904-2Cyclohexyl diphenyl phosphinecyclohexyl(diphenyl)phosphaneMFCD00046360

Show more names

CYCLOHEXYLDICyclohexyldiphenylphospinewhitextlPhosphine, cycLCyclohexyldihenylphosphinecyclohexyldiphenyl-phosphindiphenylcyclohexylphosphino

cyclohexyldiphenylphosphaneC18H21PDiphenylphosphinocyclohexaneZXKWUYWWVSKKQZ-UHFFFAOYSA-CS-W014043HY-W013327SY036763BCP05539

Database identifiers

CAS: 6372-42-5
PubChem CID: 80756
DTXSID: DTXSID6074671
UNII: 6SW83V2X43
EC Number: 228-904-2
Nikkaji: J206.971G

Properties

Computed structural properties

XLogP: 4.9
Topological polar surface area: 0 Å²
Hydrogen bond donors: 0
Hydrogen bond acceptors: 0
Rotatable bonds: 3
Heavy atoms: 19
Formal charge: 0
Complexity: 226

Physicochemical properties

Melting point: 58 · 58-62 °C(lit.)
Boiling point: 374 · 374.0±11.0 °C(Predicted)
Flash point: 230 °F · >230 °F
storage temp.: Keep in dark place,Inert atmosphere,Room temperature
form: Powder
color: White
Water Solubility: insoluble
Sensitive: Air Sensitive
InChI: InChI=1S/C18H21P/c1-4-10-16(11-5-1)19(17-12-6-2-7-13-17)18-14-8-3-9-15-18/h1-2,4-7,10-13,18H,3,8-9,14-15H2
InChIKey: ZXKWUYWWVSKKQZ-UHFFFAOYSA-N
SMILES: P(C1CCCCC1)(C1=CC=CC=C1)C1=CC=CC=C1
CAS DataBase Reference: 6372 · 6372-42-5(CAS DataBase Reference)
EPA Substance Registry System: Phosphine, cyclohexyldiphenyl- (6372-42-5)
UNSPSC Code: 12352002 · 12352002
NACRES: 22 · NA.22
Symbol(GHS): 7 · GHS07
Signal word: Warning
Hazard statements: 315 · H315-H319
Precautionary statements: 264 · P264-P280-P302+P352+P332+P313+P362+P364-P305+P351+P338+P337+P313
PPE: 95 · Eyeshields, Gloves, type N95 (US)
Risk Statements: 36 · 36/37/38
Safety Statements: 24 · 24/25
WGK Germany: 3 · 3
RTECS: 8387500 · SY8387500
TSCA: No
HS Code: 29319090 · 29319090
Storage Class: 11 · 11 - Combustible Solids

Safety & regulation

GHS classification

GHS Classification · 5 items

This chemical does not meet GHS hazard criteria for 20% (1 of 5) of reports.

Warning

H302 (40%): Harmful if swallowed [Warning Acute toxicity, oral]

P260, P261, P264, P264+P265, P270, P271, P272, P273, P280, P301+P317, P302+P352, P304+P340, P305+P351+P338, P319, P321, P330, P332+P317, P333+P317, P337+P317, P362+P364, P403+P233, P405, and P501 (click each P-code to see the statement)

Aggregated GHS information provided per 5 reports by companies from 5 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

Hazard information

Hazard Classes and CategoriesAcute Tox. 4 (40%)

Safety data

PPE: Eyeshields, Gloves, type N95 (US)
wgk: 3
tsca: No
rtecs: SY8387500
hs_code: 29319090
risk_code: 36/37/38
Signal word: Warning
Symbol(GHS): GHS07
safety_code: 24/25
Storage Class: 11 - Combustible Solids
Hazard statements: H315-H319
Precautionary statements: P264-P280-P302+P352+P332+P313+P362+P364-P305+P351+P338+P337+P313

Chemistry & industry

Applications · 3 items

DescriptionCyclohexyldiphenylphosphine is a chemical compound commonly used as a ligand in coordination chemistry and organometallic synthesis. It acts as a stabilizing agent and facilitates various catalytic reactions. This compound finds applications in pharmaceuticals, fine chemicals, and materials science industries. Cyclohexyldiphenylphosphine should be handled with caution as it may cause skin and eye irritation. It should be stored in a cool, well-ventilated area away from heat sources or open flames. Proper personal protective equipment (PPE) should be worn when handling this compound. Not for human consumption. Such as Silver(I) phosphine complexes were synthesized by a reaction of AgNO3, AgCl, and AgBr with cyclohexyl diphenylphosphine to produce 1:1, 1:2, or 1:3 molar ratios of new silver complexes[1].

Usessuzuki reaction

UsesCyclohexyldiphenylphosphine is used as ligand in coupling reaction. It is also used as a medical intermediate.