Bromomethylcyclopropane

HCID 81503CAS 7051-34-5
Substructure searchFind similar structures

Basic information

Standard SMILES
BrCC1CC1
InChIKey
AEILLAXRDHDKDY-UHFFFAOYSA-N
Molecular formula
C4H7Br
Average molar mass
135 g/mol
Monoisotopic mass
133.97311

Names & identifiers

Preferred name
Bromomethylcyclopropane
IUPAC
bromomethylcyclopropane
English name
(Bromomethyl)cyclopropane
Molecular formula
C4H7Br
Molecular weight
135

Names & synonyms

(Bromomethyl)cyclopropane7051-34-5BromomethylcyclopropaneCyclopropane, (bromomethyl)-1-(bromomethyl)cyclopropaneCyclopropanemethyl bromideD8ZPP7X54BEINECS 230-331-8DTXSID40220785(BROMO)(CYCLOPROPYL)METHANERefChem:121604DTXCID70143276
Show more names
Cyclopropylcarbinyl bromideCPMBr(Bromomethyl)cyclopr(Xiu Jiaji)cyclopropaneBroMoMethyl)cyclopropanCyclopropylmethylbromidRoflumilast impurity 18CYCLOPROPYLMETYL BROMIDE
230-331-8AEILLAXRDHDKDY-UHFFFAOYSA-NCyclopropylmethyl bromideMFCD00001306bromocyclopropylmethaneCyclopropyl bromo methanebromomethyl cyclopropanecyclopropylmethylbromide

Database identifiers

CAS
7051-34-5
PubChem CID
81503
DTXSID
DTXSID40220785
UNII
D8ZPP7X54B
EC Number
230-331-8
Nikkaji
J23.250E

Properties

Computed structural properties

XLogP
1.7
Topological polar surface area
0 Ų
Hydrogen bond donors
0
Hydrogen bond acceptors
0
Rotatable bonds
1
Heavy atoms
5

Physicochemical properties

Melting point
87 · 87-90 °C
Boiling point
105 · 105-107 °C(lit.)
Density
1.392 g/mL · 1.392 g/mL at 25 °C(lit.)
refractive index
20 · n20/D 1.457(lit.)
Flash point
107 °F · 107 °F
storage temp.
2 · Inert atmosphere,2-8°C

Safety & regulation

GHS classification

GHS Classification · 6 items

This chemical does not meet GHS hazard criteria for 0.5% (1 of 182) of reports.

Danger

H225 (57.1%): Highly Flammable liquid and vapor [Danger Flammable liquids]；H226 (42.3%): Flammable liquid and vapor [Warning Flammable liquids]；H302 (70.9%): Harmful if swallowed [Warning Acute toxicity, oral]；H315 (69.8%): Causes skin irritation [Warning Skin corrosion/irritation]；H319 (69.2%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]；H335 (68.7%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation]

P210, P233, P240, P241, P242, P243, P261, P264, P264+P265, P270, P271, P280, P301+P317, P302+P352, P303+P361+P353, P304+P340, P305+P351+P338, P319, P321, P330, P332+P317, P337+P317, P362+P364, P370+P378, P403+P233, P403+P235, P405, and P501 (click each P-code to see the statement)

Aggregated GHS information provided per 182 reports by companies from 16 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.；Reported as not meeting GHS hazard criteria per 1 of 182 reports by companies.；There are 15 notifications provided by 181 of 182 reports by companies with hazard statement code(s).；Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website.

Hazard information

Regulatory Information · 3 items

Chemical: Cyclopropane, (bromomethyl)-

Status: Active Update: 06-03-2019 https://echa.europa.eu/registration-dossier/-/registered-dossier/21443

Bromomethyl-cyclopropane: Does not have an individual approval but may be used under an appropriate group standard

Hazard Classes and CategoriesFlam. Liq. 2 (57.1%)；Flam. Liq. 3 (42.3%)；Acute Tox. 4 (70.9%)；Skin Irrit. 2 (69.8%)；Eye Irrit. 2A (69.2%)；STOT SE 3 (68.7%)

Regulatory information

Regulatory Information · 3 items

Chemical: Cyclopropane, (bromomethyl)-

Status: Active Update: 06-03-2019 https://echa.europa.eu/registration-dossier/-/registered-dossier/21443

Bromomethyl-cyclopropane: Does not have an individual approval but may be used under an appropriate group standard

Safety data

PPE
Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter
wgk
3
ridadr
UN 1993 3/PG 3
hs_code
29035990
risk_code
10-36/37/38-22
Signal word
Warning

Chemistry & industry

Applications · 4 items

Uses(Bromomethyl)cyclopropane is used in the synthesis of 1,4-dienes by iron-catalyzed cross-coupling with alkenyl Grignard reagents.

Description(Bromomethyl) cyclopropane is a cyclopropane derivative. It can be used as a synthetic building block for the introduction of the cyclopropylmethyl group. It was also used in the synthesis of 1, 4-dienes via iron-catalyzed cross-coupling with alkenyl Grignard reagents.

Uses(Bromomethyl)cyclopropane was used as a synthetic building block for the introduction of the cyclopropylmethyl group. It was also used in the synthesis of 1,4-dienes via iron-catalyzed cross-coupling with alkenyl Grignard reagents.

General DescriptionThe coupling reaction of (bromomethyl)cyclopropane with phenylmagnesium bromide was studied.

Upstream & downstream products

Suppliers50 total

国药集团化学试剂有限公司86-21-63210123 · [email protected]
衢州润东化工有限公司0570-8789886 18892685668 · [email protected]
上海阿拉丁生化科技股份有限公司400-6206333 13167063860 · [email protected]
T&W GROUP021-61551611 13296011611 · [email protected]
韶远科技（上海）有限公司021-50795510 4000665055 · [email protected]

Related reactions

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Linked notes

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