Basic information
- CAS
112-25-4- Standard SMILES
CCCCCCOCCO- InChIKey
UPGSWASWQBLSKZ-UHFFFAOYSA-N- Molecular formula
- C8H18O2
- Average molar mass
- 146.23 g/mol
- Monoisotopic mass
- 146.13067981
Overview
See also: Hexan-1-ol, ethoxylated (annotation moved to); Hexyl poly(oxyethylene) ether (annotation moved to).
Names & identifiers
- Preferred name
- Glycol monohexyl ether
- IUPAC
- 2-hexoxyethanol
- English name
- 2-(Hexyloxy)ethanol
- Molecular formula
- C8H18O2
- Molecular weight
- 146.23
Names & synonyms
2-(Hexyloxy)ethanol112-25-4Ethylene glycol monohexyl ether2-Hexyloxyethanol2-HEXOXYETHANOLEthanol, 2-(hexyloxy)-Hexyl cellosolven-Hexyl cellosolveGlycol monohexyl etherCellosolve, N-hexyl-Ethylene glycol n-hexyl etherEthanol, 2-hexyloxy-
Show more names
Ethylenegylcolmono-N-hexyletherC6E1HEXYLGLYCOLhexylcellosolve2-hexyloxy-ethanon-hexyl-cellosolv
DTXSID1026908Ethylene glycol-n-monohexyl ether7P0O8282NRDTXCID606908EGHERefChem:922359203-951-12-(hexyloxy)ethan-1-ol
Database identifiers
- CAS
112-25-4、31726-34-8- PubChem CID
- 8170
- DTXSID
DTXSID1026908- ChEMBL
CHEMBL3188016- UNII
- 7P0O8282NR
- EC Number
- 203-951-1
- Nikkaji
Properties
Computed structural properties
- XLogP
- 1.9
- Topological polar surface area
- 29.5 Ų
- Hydrogen bond donors
- 1
- Hydrogen bond acceptors
- 2
- Rotatable bonds
- 7
- Heavy atoms
- 10
- Formal charge
- 0
- Complexity
- 55.2
Experimental & physicochemical properties
SolventsSolvents -> Glycol Ethers (E Series)
SpringerMaterials PropertiesBoiling point
LogP
1.57
1.86
Density
0.8894 @ 20 °C/20 °C
Relative density (water = 1): 0.89
Color/FormWATER-WHITE LIQ
Solubility
SLIGHTLY SOL IN WATER; VERY SOL IN ALC & ETHER
Solubility in water: poor
Flash Point
195 °F OC
81.7 °C c.c.
Boiling Point
208 °C @ 760 MM HG
208.3 °C
Melting Point
-45.1 °C
-45 °C
Vapor Pressure
Safety & regulation
Safety information is for reference only and does not replace the supplier’s Safety Data Sheet (SDS), applicable regulations, or professional assessment.
GHS classification
GHS Classification
Danger
H302: Harmful if swallowed [Warning Acute toxicity, oral]
P260, P264, P270, P280, P301+P317, P301+P330+P331, P302+P352, P302+P361+P354, P304+P340, P305+P354+P338, P316, P317, P321, P330, P362+P364, P363, P405, and P501 (click each P-code to see the statement)
This chemical does not meet GHS hazard criteria for 0.2% (1 of 431) of reports.
Danger
H302 (99.5%): Harmful if swallowed [Warning Acute toxicity, oral]
Hazard information
Regulatory Information
Chemical: Poly(oxy-1,2-ethanediyl), .alpha.-hexyl-.omega.-hydroxy-
Chemical: Ethanol, 2-(hexyloxy)-
Ethanol, 2-(hexyloxy)- is listed on the EPA's Chemical Data Reporting (CDR) system. Manufacturers and importers of Ethanol, 2-(hexyloxy)- are required to report information about their production and use of this chemical to the EPA under the Toxic Substances Control Act (TSCA). (40 eCFR Part 711)
FRI - indicates a polymeric substance containing no free-radical initiator in its Inventory name but is considered to cover the designated polymer made with any free-radical initiator regardless of the amount used.
REACH registered substance: 2-hexyloxyethanol (EC: 203-951-1)
Ethylene glycol methyl ether: Does not have an individual approval but may be used under an appropriate group standard
Other Safety Information
IMAP assessments - Ethanol, 2-(hexyloxy)-: Environment tier I assessment
IMAP assessments - Ethoxylates of aliphatic alcohols (>C6): Human health tier II assessment
Fire HazardsCombustible. Above 81.7 °C explosive vapour/air mixtures may be formed.
Hazards SummaryMay cause CNS depression and kidney injury; [HSDB] A severe skin, eye, and respiratory tract irritant; The substance may have effects on the blood. [ICSC] An irritant; May be absorbed through skin; [MSDSonline] See GLYCOL ETHERS.
Chemistry & industry
Pharmacology
Absorption, Distribution and ExcretionTHESE ETHERS PENETRATE INTACT SKIN. /CELLOSOLVES/
Uses & manufacturing
Uses
Used as a high-boiling solvent; as a chemical intermediate for hexyloxyethyl phosphate and neopentanoate; [HSDB] Used as a coalescing agent in latex paints and cleaners; [eChemPortal: SIDSUNEP]
Painting (Solvents) [Category: Paint]
HIGH-BOILING SOLVENT
SOLVENT (EG, FOR SURFACE COATINGS & CLEANING SOLNS)
CHEM INT FOR HEXYLOXYETHYL PHOSPHATE & NEOPENTANOATE
U.S. Exports
(1979) No Data
(1981) No Data
U.S. Imports
(1979) No Data
(1981) No Data
U.S. Production
2023: 5,000,000 - <10,000,000 lb
(1979) No Data
(1981) No Data
Consumer UsesSolvent
Industry UsesSolvent
Methods of ManufacturingREACTION OF ETHYLENE OXIDE WITH 1-HEXANOL (PRODUCT IS ISOLATED FROM THE REACTION MIXT BY VACUUM DISTILLATION)
Household ProductsInformation on 83 consumer products that contain Ethylene glycol n-hexyl ether in the following categories is provided:
General Manufacturing Information
All Other Chemical Product and Preparation Manufacturing
Ethanol, 2-(hexyloxy)-: ACTIVE
Poly(oxy-1,2-ethanediyl), .alpha.-hexyl-.omega.-hydroxy-: ACTIVE
Related reactions
3 records
Compound notes
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