Lethane

EYES: First check the victim for contact lenses and remove if present. Flush victim's eyes with water or normal saline solution for 20 to 30 minutes while simultaneously calling a hospital or poison control center. Do not put any ointments, oils, or medication in the victim's eyes without specific instructions from a physician. IMMEDIATELY transport the victim after flushing eyes to a hospital even if no symptoms (such as redness or irritation) develop.

SMALL SPILLS AND LEAKAGE: If you spill this chemical, FIRST REMOVE ALL SOURCES OF IGNITION. Then, use absorbent paper to pick up all liquid spill material. Your contaminated clothing and absorbent paper should be sealed in a vapor-tight plastic bag for eventual disposal. Solvent wash all contaminated surfaces with 60-70% ethanol followed by washing with a soap and water solution. Do not reenter the contaminated area until the Safety Officer (or other responsible person) has verified that the area has been properly cleaned.

0.19 [mg/m3]

2.1 [mg/m3]

12 [mg/m3]

SYMPTOMATOLOGY (LARGELY INFERRED FROM ANIMAL TESTS): 1. INGESTION OF CONCENTRATED SOLN MAY LEAD TO VOMITING BECAUSE OF MUCOSAL IRRITATION. /ALIPHATIC THIOCYANATES/

SYMPTOMATOLOGY (LARGELY INFERRED FROM ANIMAL TESTS): 2. PRINCIPAL SYSTEMIC REACTION IS PROBABLY ... CENTRAL NERVOUS DEPRESSION, INTERRUPTED BY PERIODS OF RESTLESSNESS, HYPERPNEA, TONIC CONVULSIONS. AS JUDGED FROM ANIMAL TESTS, DEPRESSION MAY LAST FOR MANY DAYS. /ALIPHATIC THIOCYANATES/

SYMPTOMATOLOGY (LARGELY INFERRED FROM ANIMAL TESTS): 4. DEATH IS USUALLY DUE TO RESPIRATORY ARREST FROM PARALYSIS OF MEDULLARY CENTERS. ... 5. MASSIVE SKIN CONTAMINATION WITH ORG THIOCYANATES SOLN MAY PRODUCE SYSTEMIC POISONING ... & ... LOCAL IRRITATION & DERMATITIS. /ALIPHATIC THIOCYANATES/

SYMPTOMATOLOGY (LARGELY INFERRED FROM ANIMAL TESTS): 6. IN NONFATAL CASES EVIDENCE OF INJURIES TO LIVER AND KIDNEYS MAY APPEAR. /ALIPHATIC THIOCYANATES/

For more Human Toxicity Excerpts (Complete) data for LETHANE 384 (7 total), please visit the HSDB record page.

... TREMORS, PARALYSIS, SPASTICITY, AND EVEN OPISTHOTONOS HAVE BEEN DESCRIBED ... IN RABBITS GIVEN LETHANE 384 BY VARIOUS ROUTES ... .

... METHYL, ETHYL & ISOPROPYL THIOCYANATES & LETHANE 384 ARE RAPIDLY ACTING POISONS ... THEY PRODUCE CENTRAL NERVOUS DEPRESSION, USUALLY WITH TRANSIENT PERIOD OF RESP STIMULATION, PROGRESSING PROMPTLY TO DEATH FROM RESP FAILURE.

As the federal pesticide law FIFRA directs, EPA is conducting a comprehensive review of older pesticides to consider their health and environmental effects and make decisions about their future use. Under this pesticide reregistration program, EPA examines health and safety data for pesticide active ingredients initially registered before November 1, 1984, and determines whether they are eligible for reregistration. In addition, all pesticides must meet the new safety standard of the Food Quality Protection Act of 1996. Pesticides for which EPA had not issued Registration Standards prior to the effective date of FIFRA, as amended in 1988, were divided into three lists based upon their potential for human exposure and other factors, with List B containing pesticides of greater concern and List D pesticides of less concern. Butoxyethoxy)ethyl thiocyanate is found on List C. Case No: 3142; Pesticide type: insecticide; Case Status: No products containing the pesticide are actively registered ... The case /is characterized/ as "cancelled." Under FIFRA, pesticide producers may voluntarily cancel their registered products. EPA also may cancel pesticide registrations if registrants fail to pay required fees or make/meet certain reregistration commitments, or if EPA reaches findings of unreasonable adverse effects.; Active ingredient (AI): Butoxyethoxy)ethyl thiocyanate; AI Status: The active ingredient is no longer contained in any registered pesticide products ... "cancelled."