HomeMCPWorkbenchSkills
HomeWorkbenchNotificationsMe
llms.txt · MCP GuidePrivacy Policy · Terms of Service · Supportv1.8.0
  1. Home
  2. /Compound

Riboflavin 5'-(dihydrogen phosphate), monosodium salt

HCID 82017495
New noteNew reactionRequest quotes
Print preview
Basic informationNames & identifiersPropertiesSafety & regulationChemistry & industryRelated reactionsCompound notes
Substructure searchFind similar structures

Basic information

CAS
130-40-5
Standard SMILES
Cc1cc2nc3c(=O)[nH]c(=O)nc-3n(C[C@@H]([O-])[C@@H](O)[C@@H](O)COP(=O)(O)O)c2cc1C.[Na+]
InChIKey
USEQDWWEOPFEGH-LQDWTQKMSA-N
Molecular formula
C17H20N4NaO9P
Average molar mass
478.3 g/mol
Monoisotopic mass
478.08655951

Names & identifiers

Preferred name
Riboflavin 5'-(dihydrogen phosphate), monosodium salt
IUPAC
sodium (2R,3R,4S)-1-(7,8-dimethyl-2,4-dioxobenzo[g]pteridin-10-yl)-3,4-dihydroxy-5-phosphonooxypentan-2-olate
English name
Riboflavin 5'-Monophosphate Sodium Salt
Molecular formula
C17H21N4O9P.Na
Molecular weight
479.33

Names & synonyms

Riboflavin 5'-(dihydrogen phosphate), monosodium saltRiboflavin Phosphate Sodium Salt (~70%)AKOS022189130sodium;(2R,3R,4S)-1-(7,8-dimethyl-2,4-dioxobenzo[g]pteridin-10-yl)-3,4-dihydroxy-5-phosphonooxypentan-2-olateRIBOFLAVIN SODIUM PHOSPHATEFLAVIN MONONUCLEOTIDERIBOFLAVIN-5-PHOSPHATERIBOFLAVIN 5'-PHOSPHATE SODIUMRiboSODIUM RIBOFLAVIN PHOSPHATERiboflavin Phosphate Sodium Salt(2R,3S,4S)-5-(7,8-dimethyl-2,4-dioxo-3,4-dihydrobenzo[g]pteridin-10(2H)-yl)-2,3,4-trihydroxypentyl dihydrogen phosphate
Show more names
Tenofovir Impurity 155Vitamin B2 Sodium Phosphate

Database identifiers

CAS
130-40-5
PubChem CID
82017495

Properties

Computed structural properties

Topological polar surface area
204 Ų
Hydrogen bond donors
5
Hydrogen bond acceptors
10
Rotatable bonds
7
Heavy atoms
32
Formal charge
0
Complexity
850

Physicochemical properties

Melting point
300 °C · >300°C
alpha
20 · [α]D20 +38~+43° (c=1.5, dil. HCl) (Calculated on dehydrous basis)
FEMA
2976 · 2976 | QUININE HYDROCHLORIDE
refractive index
41 ° · 41 ° (C=1.5, 5mol/L HCl)
storage temp.
2 · 2-8°C
solubility
2 O: · H2O: soluble50mg/mL, clear, orange
form
powder
color
Yellow to Dark Orange
biological source
synthetic
optical activity
20 · [α]20/D +37 to +42°, c = 1.5 in 5 M HCl(lit.)
Water Solubility
almost transparency
ε(extinction coefficient)
12.5 at · 12.5 at 445nm at 1mM
Merck
14 · 14,8201
BRN
4106529 · 4106529
Stability
Stable. Incompatible with strong oxidizing agents, reducing agents, bases, calcium, metallic salts. Protect from light, air and moisture.

Safety & regulation

Safety information is for reference only and does not replace the supplier’s Safety Data Sheet (SDS), applicable regulations, or professional assessment.

Hazard information

Regulatory InformationRiboflavin 5-phosphate sodium: Does not have an individual approval but may be used under an appropriate group standard

Safety data

F
3-8-10
wgk
3
tsca
TSCA listed
hs_code
29362300
risk_code
36/38
Signal word
Warning
Symbol(GHS)
GHS07
hazard_code
Xi
safety_code
22-24/25-37/39-26
Storage Class
11 - Combustible Solids
Hazard statements
H315-H319-H335
Precautionary statements
P261-P271-P280

Chemistry & industry

Applications · 5 items

DescriptionRiboflavin-5-phosphate sodium (sodium FMN,130-40-5) consist mainly monosodium salt of Riboflavin 5-phophate (FMN), the 5-monophosphate ester of riboflavin. Riboflavin-5-phosphate sodium is produced by direct reaction of riboflavin with a phosphorylating agent such as phosphorous oxychloride in an organic solvent. Riboflavin 5-phophate (FMN) is essential as a coenzyme in various enzymic reactions in the body and is therefore used in the form of its salts, especially in the form of sodium FMN, as additive to drugs and human and animal food. Sodium FMN is also used as starting material for flavin adenine dinucleotide which is employed for treating vitamin B2 deficiency. It is used as a yellow food color additive (E106). Riboflavin 5-phosphate sodium is fairly stable in air but is hygroscopic and sensitive to heat and light. The product may be stored for 33 months from the date of manufacture in the unopened original container and at a temperature below 15 °C.

UsesRiboflavin 5′-monophosphate sodium salt hydrate has been used:as a component of assay buffer to determine the luminescence of L. lactis cellsas a component of the reaction mixture in nitric oxide synthase (NOS) enzymatic activity assayin the high performance liquid chromatography (HPLC) analysis of Flavin mononucleotide (FMN) cyclase productsin luciferase assay with firefly luciferase

UsesOne of the bioactive forms of Riboflavin. Nutritional factor found in milk, eggs, malted barley, liver, kidney, heart, leafy vegetables. Richest natural source is yeast. Minute amounts present in all plant and animal cells. Vitamin (enzyme cofactor).

Usesantibacterial. Riboflavin 5′-monophosphate sodium salt was used as water-soluble model drug in a combined conventional inkjet printing technology with flexographic printing for the fabrication of drug delivery systems.It may be employed as initiator for the photo-initiated polymerization of acrylamide.It may be employed in chronoamperometric assay for vanadium ions. Riboflavin 5′-monophosphate is also known as flavin mononucleotide (FMN). FMN is a water-soluble micronutrient. It is enzymatically produced from riboflavin (RF).Riboflavin 5′-monophosphate is one of the constituent of enzyme cofactor flavin-adenine dinucleotide.

General DescriptionRiboflavin 5'-Monophosphate Sodium Salt Hydrate (Vitamin B2 Salt) may serve as both a carbon source and reducing agent for synthesising luminescent carbon dots and carbon-encapsulated metal (Au, Pt, Pd) particles. Simultaneous hydrothermal heating of B2salt and metal salt solutions yields water-soluble carbon dots in the supernatant and carbon-coated metal particles in the precipitate. The resulting carbon dots exhibit dual nitrogen and phosphorus doping, enhancing their luminescent properties, while the metal-loaded carbon particles hold significant potential for catalytic applications.

Related reactions

0 records
New reaction record

No reaction records under the current filter.

Compound notes

Loading…

On this pageBasic informationNames & identifiersPropertiesSafety & regulationChemistry & industryRelated reactionsCompound notes
More actions
New noteNew reactionRequest quotes
Major Application
pharmaceutical (small molecule)
Cosmetics Ingredients Functions
SKIN CONDITIONING
InChIKey
OHSHFZJLPYLRIP-BMZHGHOISA-M
SMILES
[Na+].Cc1cc2N=C3C(=O)NC(=O)N=C3N(C[C@H](O)[C@H](O)[C@H](O)COP(O)([O-])=O)c2cc1C
LogP
-2.193 · -2.193 (est)
CAS DataBase Reference
130 · 130-40-5(CAS DataBase Reference)
Substances Added to Food (formerly EAFUS)
5 · RIBOFLAVIN 5'-PHOSPHATE, SODIUM
FDA 21 CFR
184.1697 · 184.1697
EWG's Food Scores
1 · 1
FDA UNII
957 E53WV42 · 957E53WV42
EPA Substance Registry System
5 · Riboflavin 5'-(dihydrogen phosphate), monosodium salt (130-40-5)
UNSPSC Code
41116107 · 41116107
NACRES
51 · NA.51
Symbol(GHS)
7 · GHS07
Signal word
Warning
Hazard statements
315 · H315-H319-H335
Precautionary statements
261 · P261-P271-P280
Hazard Codes
Xi
Risk Statements
36 · 36/38
Safety Statements
22 · 22-24/25-37/39-26
WGK Germany
3 · 3
F
3 · 3-8-10
TSCA
TSCA listed
HS Code
29362300 · 29362300
Storage Class
11 · 11 - Combustible Solids

Upstream & downstream products

Upstream raw materials

Riboflavin

Additional notes

DefinitionChEBI: Riboflavin sodium phosphate is a ribitol phosphate and a vitamin B2. It is functionally related to a riboflavin.