Diethylene glycol dibutyl ether

HCID 8210CAS 112-73-2

Basic information

Standard SMILES
CCCCOCCOCCOCCCC
InChIKey
KZVBBTZJMSWGTK-UHFFFAOYSA-N
Molecular formula
C12H26O3
Average molar mass
218.33 g/mol
Monoisotopic mass
218.18819469

Names & identifiers

Preferred name
Diethylene glycol dibutyl ether
IUPAC
1-[2-(2-butoxyethoxy)ethoxy]butane
English name
Diethylene Glycol Dibutyl Ether
Molecular formula
C12H26O3
Molecular weight
218.33

Names & synonyms

112-73-2DIETHYLENE GLYCOL DIBUTYL ETHERBis(2-butoxyethyl) etherDibutyl carbitolButyl diglyme5,8,11-TrioxapentadecaneEther, bis(butoxyethyl)2-Butoxyethyl etherDiethylene glycol di-n-butyl ether2,2'-Dibutoxyethyl etherButexEther, bis(2-butoxyethyl)
Show more names
Diethylene Glycol Di-n-butylDiethylene glycol diBIS(BUTOXYETHYL)ETHER
Dibutylether diethylenglykoluButane, 1,1'-[oxybis(2,1-ethanediyloxy)]bis-Diethyleneglycoldibutyl etherDTXSID8025046EINECS 204-001-9Dibutylether diethylenglykolu [Czech]F8P3DHG73ZBRN 1750713

Database identifiers

CAS
112-73-2
PubChem CID
8210
DTXSID
DTXSID8025046
ChEMBL
CHEMBL1485392
UNII
F8P3DHG73Z
EC Number
204-001-9
Nikkaji
J36.822I

Properties

Computed structural properties

XLogP
1.9
Topological polar surface area
27.7 Ų
Hydrogen bond donors
0
Hydrogen bond acceptors
3
Rotatable bonds
12
Heavy atoms
15

Experimental & physicochemical properties

Density · 2 items

0.885 (USCG, 1999) - Less dense than water; will float

0.8853 @ 20°C

Solubilityless than 1 mg/mL at 72 °F (NTP, 1992)
Flash Point · 2 items

245 °F (NTP, 1992)

245.0 °F [CAMEO] VP from ChemIDplus

Boiling Point · 2 items

493 °F at 760 mmHg (NTP, 1992)

256 °C @760 [mm Hg]

Melting Point-76 °F (NTP, 1992)
Vapor Densitygreater than 1 (NTP, 1992) (Relative to Air)

Physicochemical properties

Melting point
-60 °C · -60 °C (lit.)
Boiling point
256 °C · 256 °C (lit.)
Density
0.885 g/mL · 0.885 g/mL at 25 °C (lit.)
vapor density
1 · >1 (vs air)
vapor pressure
0.01 mm · <0.01 mm Hg ( 20 °C)
refractive index
20 · n20/D 1.423(lit.)

Safety & regulation

GHS classification

GHS Classification · 3 items

This chemical does not meet GHS hazard criteria for 94.6% (192 of 203) of all reports.

Not Classified;Reported as not meeting GHS hazard criteria by 192 of 203 companies (only 5.4% companies provided GHS information). For more detailed information, please visit ECHA C&L website.

Aggregated GHS information provided per 203 reports by companies from 7 notifications to the ECHA C&L Inventory.;Reported as not meeting GHS hazard criteria per 192 of 203 reports by companies.;There are 5 notifications provided by 11 of 203 reports by companies with hazard statement code(s).;Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website.

Hazard information

Regulatory Information · 5 items

Chemical: Butane, 1,1'-[oxybis(2,1-ethanediyloxy)]bis-

Butane, 1,1'-[oxybis(2,1-ethanediyloxy)]bis- is listed on the EPA's Chemical Data Reporting (CDR) system. Manufacturers and importers of Butane, 1,1'-[oxybis(2,1-ethanediyloxy)]bis- are required to report information about their production and use of this chemical to the EPA under the Toxic Substances Control Act (TSCA). (40 eCFR Part 711)

S - indicates a substance that is identified in a final Significant New Use Rule.

Status: Active Update: 10-07-2019 https://echa.europa.eu/registration-dossier/-/registered-dossier/5839

Butane, 1,1'-[oxybis(2,1-ethanediyloxy)]bis-: Does not have an individual approval but may be used under an appropriate group standard

Fire HazardsSpecial Hazards of Combustion Products: Vapor may travel considerable distance to a source of ignition and flash back. (USCG, 1999)
Health HazardsMay be harmful by inhalation, ingestion and skin absorption. Causes eye and skin irritation. Material is irritating to mucous membrane and upper respiratory tract. (USCG, 1999)
Hazards SummaryOxidizes in air and may cause explosive peroxides; A skin and eye irritant; [CAMEO] See Monoglyme.
Reactive GroupEthers
Reactivity AlertsPeroxidizable Compound

Safety & protection

Fire FightingFire Extinguishing Agents: Water spray, dry chemical, alcohol foam. (USCG, 1999)
First Aid · 1 item

EYES: First check the victim for contact lenses and remove if present. Flush victim's eyes with water or normal saline solution for 20 to 30 minutes while simultaneously calling a hospital or poison control center. Do not put any ointments, oils, or medication in the victim's eyes without specific instructions from a physician. IMMEDIATELY transport the victim after flushing eyes to a hospital even if no symptoms (such as redness or irritation) develop.;SKIN: IMMEDIATELY flood affected skin with water while removing and isolating all contaminated clothing. Gently wash all affected skin areas thoroughly with soap and water. If symptoms such as redness or irritation develop, IMMEDIATELY call a physician and be prepared to transport the victim to a hospital for treatment.;INHALATION: IMMEDIATELY leave the contaminated area; take deep breaths of fresh air. If symptoms (such as wheezing, coughing, shortness of breath, or burning in the mouth, throat, or chest) develop, call a physician and be prepared to transport the victim to a hospital. Provide proper respiratory protection to rescuers entering an unknown atmosphere. Whenever possible, Self-Contained Breathing Apparatus (SCBA) should be used; if not available, use a level of protection greater than or equal to that advised under Protective Clothing.;INGESTION: DO NOT INDUCE VOMITING. If the victim is conscious and not convulsing, give 1 or 2 glasses of water to dilute the chemical and IMMEDIATELY call a hospital or poison control center. Be prepared to transport the victim to a hospital if advised by a physician. If the victim is convulsing or unconscious, do not give anything by mouth, ensure that the victim's airway is open and lay the victim on his/her side with the head lower than the body. DO NOT INDUCE VOMITING. IMMEDIATELY transport the victim to a hospital. (NTP, 1992)

Nonfire Spill Response · 1 item

SMALL SPILLS AND LEAKAGE: If you spill this chemical, FIRST REMOVE ALL SOURCES OF IGNITION. Then, use absorbent paper to pick up all liquid spill material. Your contaminated clothing and absorbent paper should be sealed in a vapor-tight plastic bag for eventual disposal. Solvent wash all contaminated surfaces with 60-70% ethanol followed by washing with a soap and water solution. Do not reenter the contaminated area until the Safety Officer (or other responsible person) has verified that the area has been properly cleaned.;STORAGE PRECAUTIONS: You should keep this material in a tightly closed container under an inert atmosphere, and store it at refrigerated temperatures. (NTP, 1992)

Protective Action Criteria (PAC) · 3 items

12 [ppm]

130 [ppm]

770 [ppm]

Personal Protective Equipment (PPE)Wear self-contained breathing apparatus, rubber boots and heavy rubber gloves. (USCG, 1999)

Toxicology

Adverse EffectsNeurotoxin - Acute solvent syndrome

Regulatory information

Regulatory Information · 5 items

Chemical: Butane, 1,1'-[oxybis(2,1-ethanediyloxy)]bis-

Butane, 1,1'-[oxybis(2,1-ethanediyloxy)]bis- is listed on the EPA's Chemical Data Reporting (CDR) system. Manufacturers and importers of Butane, 1,1'-[oxybis(2,1-ethanediyloxy)]bis- are required to report information about their production and use of this chemical to the EPA under the Toxic Substances Control Act (TSCA). (40 eCFR Part 711)

S - indicates a substance that is identified in a final Significant New Use Rule.

Status: Active Update: 10-07-2019 https://echa.europa.eu/registration-dossier/-/registered-dossier/5839

Butane, 1,1'-[oxybis(2,1-ethanediyloxy)]bis-: Does not have an individual approval but may be used under an appropriate group standard

Safety data

PPE
Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)
wgk
1
tsca
TSCA listed
rtecs
KN0350000
hs_code
29091900
Toxicity
LD50 orally in Rabbit: 3900 mg/kg LD50 dermal Rabbit 3555 mg/kg

Chemistry & industry

Uses & manufacturing

Uses · 2 items

Used as a solvent with applications in coatings and inks, vinyl chloride dispersion, and uranium extraction; [Hawley]

Painting (Solvents) [Category: Paint]

U.S. Production2023: 131,154 lb;2022: 141,941 lb;2021: 66,002 lb;2020: 609,534 lb
Industry UsesAlloys;Solvent;Not Known or Reasonably Ascertainable;Corrosion inhibitor;Flux agent
General Manufacturing Information · 2 items

Not Known or Reasonably Ascertainable;All Other Chemical Product and Preparation Manufacturing;Primary Metal Manufacturing

Butane, 1,1'-[oxybis(2,1-ethanediyloxy)]bis-: ACTIVE

Applications · 3 items

UsesButyl diglyme is used to extract gold from hydrochloric acid solutions containing other metals. Treatment of the diglyme extract with hydrogen or oxalic acid precipitates the ionic gold as gold powder.

UsesExtraction of precious metalsDiethylene glycol dibutyl ether is used as a solvent in Grignard reactions. It is also used as solvents in gold refining, decorative inks for ceramics and digital inks. It finds application in electrochemistry, gas absorption, extractant and high boiling reaction medium. It is also used in fuel, lubricant, textile and medicine.

General DescriptionColorless liquid. Floats on water.

Upstream & downstream products

Upstream raw materials

Suppliers50 total

国药集团化学试剂有限公司86-21-63210123 · [email protected]
梯希爱(上海)化成工业发展有限公司021-67121386 · [email protected]
上海阿拉丁生化科技股份有限公司400-6206333 13167063860 · [email protected]
温州共赢化学有限公司+86-0086-577-64498589 +86-15355981851 · [email protected]
爱斯特(成都)生物制药股份有限公司+86-28-85122536 85324413 · [email protected]

Related reactions

5 records

Linked notes

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