Basic information
- Standard SMILES
CCCCOCCOCCOCCCC- InChIKey
KZVBBTZJMSWGTK-UHFFFAOYSA-N- Molecular formula
- C12H26O3
- Average molar mass
- 218.33 g/mol
- Monoisotopic mass
- 218.18819469
Names & identifiers
- Preferred name
- Diethylene glycol dibutyl ether
- IUPAC
- 1-[2-(2-butoxyethoxy)ethoxy]butane
- English name
- Diethylene Glycol Dibutyl Ether
- Molecular formula
- C12H26O3
- Molecular weight
- 218.33
Names & synonyms
Show more names
Database identifiers
- CAS
112-73-2- PubChem CID
- 8210
- DTXSID
DTXSID8025046- ChEMBL
CHEMBL1485392- UNII
- F8P3DHG73Z
- EC Number
- 204-001-9
- Nikkaji
- J36.822I
Properties
Computed structural properties
- XLogP
- 1.9
- Topological polar surface area
- 27.7 Ų
- Hydrogen bond donors
- 0
- Hydrogen bond acceptors
- 3
- Rotatable bonds
- 12
- Heavy atoms
- 15
- Formal charge
- 0
- Complexity
- 95
Experimental & physicochemical properties
Density
0.885 (USCG, 1999) - Less dense than water; will float
0.8853 @ 20°C
Flash Point
245 °F (NTP, 1992)
245.0 °F [CAMEO] VP from ChemIDplus
Boiling Point
493 °F at 760 mmHg (NTP, 1992)
256 °C @760 [mm Hg]
Vapor Pressure
0.02 mmHg at 68 °F (NTP, 1992)
0.02 [mmHg]
Physical Description
Diethylene glycol dibutyl ether is a colorless liquid. Floats on water. (USCG, 1999)
Liquid; Wet Solid; Liquid
Colorless liquid that floats on water; [CAMEO]
Physicochemical properties
- Melting point
- -60 °C · -60 °C (lit.)
- Boiling point
- 256 °C · 256 °C (lit.)
- Density
- 0.885 g/mL · 0.885 g/mL at 25 °C (lit.)
- vapor density
- 1 · >1 (vs air)
- vapor pressure
- 0.01 mm · <0.01 mm Hg ( 20 °C)
- refractive index
- 20 · n20/D 1.423(lit.)
- Flash point
- 243 °F · 243 °F
- storage temp.
- 30 °C · Store below +30°C.
- solubility
- 3 g/l · 3g/l
- form
- Liquid
- color
- Colorless
- Viscosity
- 2.692 mm2/s · 2.692mm2/s
- Water Solubility
- 0.3 g/100 · 0.3 g/100 mL (20 ºC)
- Thermal Conductivity
- 0.146 W/ · 0.146 W/(m·K) at 25 ℃
- Specific Heat Capacity
- 2.07 J/ · Cp(liquid): 2.07 J/(g·K), at 25℃
- BRN
- 1750713 · 1750713
- Henry's Law Constant
- 2.5 · 2.5×100 mol/(m3Pa) at 25℃, Brockbank (2013)
- InChI
- 1S/C12H26O3/c1-3-5-7-13-9-11-15-12-10-14-8-6-4-2/h3-12H2,1-2H3
- InChIKey
- KZVBBTZJMSWGTK-UHFFFAOYSA-N
- SMILES
- CCCCOCCOCCOCCCC
- LogP
- 1.92 at · 1.92 at 25℃
- CAS DataBase Reference
- 112 · 112-73-2(CAS DataBase Reference)
- FDA UNII
- 8 P3DHG73Z · F8P3DHG73Z
- NIST Chemistry Reference
- 1 · Butane, 1,1'-[oxybis(2,1-ethanediyloxy)]bis-(112-73-2)
- EPA Substance Registry System
- Diethylene glycol dibutyl ether (112-73-2)
- UNSPSC Code
- 12352112 · 12352112
- NACRES
- 22 · NA.22
- Symbol(GHS)
- 7 · GHS07
- Signal word
- Warning
- Hazard statements
- 319 · H319-H303-H313-H315-H335
- Precautionary statements
- 264 · P264-P280-P305+P351+P338+P337+P313-P261-P280a-P304+P340-P305+P351+P338-P405-P501a
- PPE
- Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)
- Safety Statements
- 23 · 23-24/25
- WGK Germany
- 1 · 1
- RTECS
- 350000 · KN0350000
- Autoignition Temperature
- 268 °C · 268 °C
- TSCA
- TSCA listed
- HS Code
- 29091900 · 29091900
- Storage Class
- 10 · 10 - Combustible liquids
- Toxicity
- 50 orally · LD50 orally in Rabbit: 3900 mg/kg LD50 dermal Rabbit 3555 mg/kg
- REACH Registrations
- Active
Safety & regulation
GHS classification
GHS Classification
This chemical does not meet GHS hazard criteria for 94.6% (192 of 203) of all reports.
Not Classified;Reported as not meeting GHS hazard criteria by 192 of 203 companies (only 5.4% companies provided GHS information). For more detailed information, please visit ECHA C&L website.
Aggregated GHS information provided per 203 reports by companies from 7 notifications to the ECHA C&L Inventory.;Reported as not meeting GHS hazard criteria per 192 of 203 reports by companies.;There are 5 notifications provided by 11 of 203 reports by companies with hazard statement code(s).;Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website.
Hazard information
Regulatory Information
Chemical: Butane, 1,1'-[oxybis(2,1-ethanediyloxy)]bis-
Butane, 1,1'-[oxybis(2,1-ethanediyloxy)]bis- is listed on the EPA's Chemical Data Reporting (CDR) system. Manufacturers and importers of Butane, 1,1'-[oxybis(2,1-ethanediyloxy)]bis- are required to report information about their production and use of this chemical to the EPA under the Toxic Substances Control Act (TSCA). (40 eCFR Part 711)
S - indicates a substance that is identified in a final Significant New Use Rule.
Status: Active Update: 10-07-2019 https://echa.europa.eu/registration-dossier/-/registered-dossier/5839
Butane, 1,1'-[oxybis(2,1-ethanediyloxy)]bis-: Does not have an individual approval but may be used under an appropriate group standard
Reactivity Profile
DIETHYLENE GLYCOL DIBUTYL ETHER may react violently with strong oxidizing agents. Incompatible with nitric acid. May form salts with strong acids and addition complexes with Lewis acids. In other reactions, which typically involve the breaking of the carbon-oxygen bond, relatively inert.
Safety & protection
First Aid
EYES: First check the victim for contact lenses and remove if present. Flush victim's eyes with water or normal saline solution for 20 to 30 minutes while simultaneously calling a hospital or poison control center. Do not put any ointments, oils, or medication in the victim's eyes without specific instructions from a physician. IMMEDIATELY transport the victim after flushing eyes to a hospital even if no symptoms (such as redness or irritation) develop.;SKIN: IMMEDIATELY flood affected skin with water while removing and isolating all contaminated clothing. Gently wash all affected skin areas thoroughly with soap and water. If symptoms such as redness or irritation develop, IMMEDIATELY call a physician and be prepared to transport the victim to a hospital for treatment.;INHALATION: IMMEDIATELY leave the contaminated area; take deep breaths of fresh air. If symptoms (such as wheezing, coughing, shortness of breath, or burning in the mouth, throat, or chest) develop, call a physician and be prepared to transport the victim to a hospital. Provide proper respiratory protection to rescuers entering an unknown atmosphere. Whenever possible, Self-Contained Breathing Apparatus (SCBA) should be used; if not available, use a level of protection greater than or equal to that advised under Protective Clothing.;INGESTION: DO NOT INDUCE VOMITING. If the victim is conscious and not convulsing, give 1 or 2 glasses of water to dilute the chemical and IMMEDIATELY call a hospital or poison control center. Be prepared to transport the victim to a hospital if advised by a physician. If the victim is convulsing or unconscious, do not give anything by mouth, ensure that the victim's airway is open and lay the victim on his/her side with the head lower than the body. DO NOT INDUCE VOMITING. IMMEDIATELY transport the victim to a hospital. (NTP, 1992)
Nonfire Spill Response
SMALL SPILLS AND LEAKAGE: If you spill this chemical, FIRST REMOVE ALL SOURCES OF IGNITION. Then, use absorbent paper to pick up all liquid spill material. Your contaminated clothing and absorbent paper should be sealed in a vapor-tight plastic bag for eventual disposal. Solvent wash all contaminated surfaces with 60-70% ethanol followed by washing with a soap and water solution. Do not reenter the contaminated area until the Safety Officer (or other responsible person) has verified that the area has been properly cleaned.;STORAGE PRECAUTIONS: You should keep this material in a tightly closed container under an inert atmosphere, and store it at refrigerated temperatures. (NTP, 1992)
Protective Action Criteria (PAC)
12 [ppm]
130 [ppm]
770 [ppm]
Toxicology
Regulatory information
Regulatory Information
Chemical: Butane, 1,1'-[oxybis(2,1-ethanediyloxy)]bis-
Butane, 1,1'-[oxybis(2,1-ethanediyloxy)]bis- is listed on the EPA's Chemical Data Reporting (CDR) system. Manufacturers and importers of Butane, 1,1'-[oxybis(2,1-ethanediyloxy)]bis- are required to report information about their production and use of this chemical to the EPA under the Toxic Substances Control Act (TSCA). (40 eCFR Part 711)
S - indicates a substance that is identified in a final Significant New Use Rule.
Status: Active Update: 10-07-2019 https://echa.europa.eu/registration-dossier/-/registered-dossier/5839
Butane, 1,1'-[oxybis(2,1-ethanediyloxy)]bis-: Does not have an individual approval but may be used under an appropriate group standard
Safety data
- PPE
- Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)
- wgk
- 1
- tsca
- TSCA listed
- rtecs
- KN0350000
- hs_code
- 29091900
- Toxicity
- LD50 orally in Rabbit: 3900 mg/kg LD50 dermal Rabbit 3555 mg/kg
- Signal word
- Warning
- Symbol(GHS)
- GHS07
- safety_code
- 23-24/25
- Storage Class
- 10 - Combustible liquids
- Hazard statements
- H319-H303-H313-H315-H335
- REACH Registrations
- Active
- Autoignition Temperature
- 268 °C
- Precautionary statements
- P264-P280-P305+P351+P338+P337+P313-P261-P280a-P304+P340-P305+P351+P338-P405-P501a
Chemistry & industry
Uses & manufacturing
Uses
Used as a solvent with applications in coatings and inks, vinyl chloride dispersion, and uranium extraction; [Hawley]
Painting (Solvents) [Category: Paint]
General Manufacturing Information
Not Known or Reasonably Ascertainable;All Other Chemical Product and Preparation Manufacturing;Primary Metal Manufacturing
Butane, 1,1'-[oxybis(2,1-ethanediyloxy)]bis-: ACTIVE
Applications
UsesButyl diglyme is used to extract gold from hydrochloric acid solutions containing other metals. Treatment of the diglyme extract with hydrogen or oxalic acid precipitates the ionic gold as gold powder.
UsesExtraction of precious metalsDiethylene glycol dibutyl ether is used as a solvent in Grignard reactions. It is also used as solvents in gold refining, decorative inks for ceramics and digital inks. It finds application in electrochemistry, gas absorption, extractant and high boiling reaction medium. It is also used in fuel, lubricant, textile and medicine.
General DescriptionColorless liquid. Floats on water.
Upstream & downstream products
Upstream raw materials
Suppliers50 total
Related reactions
Linked notes
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