2-Amino-6-(trifluoromethyl)pyridine (HCID 821024)

Names & identifiers

Preferred name: 2-Amino-6-(trifluoromethyl)pyridine
IUPAC: 6-(trifluoromethyl)pyridin-2-amine
English name: 2-Amino-6-(trifluoromethyl)pyridine
Molecular formula: C6H5F3N2
Molecular weight: 162.11

Names & synonyms

2-Amino-6-(trifluoromethyl)pyridine34486-24-3DTXSID00356271RefChem:464703DTXCID10307330636-458-96-(trifluoromethyl)pyridin-2-amineMFCD030938686-(trifluoromethyl)-2-pyridinylamineEN300-614962-Pyridinamine, 6-(trifluoromethyl)-6-(trifluoromethyl)-2-pyridylamine

Show more names

4-(TRIFLUOROMETHYL)PYRIDIN-2-AMINE2-Amino-6-(trifL6-trifluromethylpyridin-2-amine6-trifluoromethyl-2-pyridinamine2-Amino-6-(trifloromethyl)pyridine6-TrifluoroMethyl-pyridin-2-ylaMine

2-amino-6-trifluoromethylpyridine6-(trifluoromethyl)-2-pyridinamineAQ-776/42801241SCHEMBL181081SCHEMBL21855912SCHEMBL305316876-trifluoromethylpyridin-2-aminePBPDHPGJRZUHJW-UHFFFAOYSA-N

Database identifiers

CAS: 34486-24-3
PubChem CID: 821024
DTXSID: DTXSID00356271
EC Number: 636-458-9
Nikkaji: J2.152.094B

Properties

Computed structural properties

XLogP: 1.4
Topological polar surface area: 38.9 Å²
Hydrogen bond donors: 1
Hydrogen bond acceptors: 5
Rotatable bonds: 0
Heavy atoms: 11
Formal charge: 0
Complexity: 134

Physicochemical properties

Melting point: 85 · 85-89 °C
Boiling point: 192.1 · 192.1±40.0 °C(Predicted)
Density: 1.368 · 1.368±0.06 g/cm3(Predicted)
storage temp.: 2 · under inert gas (nitrogen or Argon) at 2–8 °C
solubility: soluble in Methanol
form: powder to crystal
pka: 3.13 · 3.13±0.24(Predicted)
color: Light yellow to Brown to Dark green
Sensitive: Hygroscopic
BRN: 473259 · 473259
InChI: InChI=1S/C6H5F3N2/c7-6(8,9)4-2-1-3-5(10)11-4/h1-3H,(H2,10,11)
InChIKey: NFYYDQMFURPHCC-UHFFFAOYSA-N
SMILES: C1(N)=NC(C(F)(F)F)=CC=C1
CAS DataBase Reference: 34486 · 34486-24-3(CAS DataBase Reference)
UNSPSC Code: 12352100 · 12352100
NACRES: 22 · NA.22
Symbol(GHS): 6 · GHS06
Signal word: Danger
Hazard statements: 300 · H300-H315-H317-H319-H335
Precautionary statements: 280 · P280-P301+P310+P330-P302+P352-P305+P351+P338
target organs: Respiratory system
PPE: 2 · Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges
Hazard Codes: T,Xi,Xn
Risk Statements: 25 · 25-36/37/38-43-20/21/22
Safety Statements: 26 · 26-36/37-45-36
RIDADR: 2811 · UN 2811 6.1/PG 1
WGK Germany: 3 · 3
Hazard Note: Irritant/Toxic
HazardClass: IRRITANT, TOXIC
PackingGroup: III
HS Code: 29333990 · 29333990
Storage Class: 6.1 B · 6.1B - Non-combustible acute toxic Cat. 1 and 2very toxic hazardous materials
Hazard Classifications: 2 OralEye · Acute Tox. 2 OralEye Irrit. 2Skin Irrit. 2Skin Sens. 1STOT SE 3
Limited Quantities: 5 kg · 5.0 kg (11 lbs) (solid)
Excepted Quantities: Max Inner Pack (30g or 30ml) and Max Outer Pack (1Kg or 1L)

Safety & regulation

GHS classification

GHS Classification · 4 items

Danger

H300 (83.7%): Fatal if swallowed [Danger Acute toxicity, oral]

P261, P264, P264+P265, P270, P271, P272, P280, P301+P316, P302+P352, P304+P340, P305+P351+P338, P317, P319, P321, P330, P332+P317, P333+P317, P337+P317, P362+P364, P403+P233, P405, and P501 (click each P-code to see the statement)

Aggregated GHS information provided per 49 reports by companies from 8 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

Hazard information

Hazard Classes and CategoriesAcute Tox. 2 (83.7%)

Safety data

PPE: Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges
wgk: 3
ridadr: UN 2811 6.1/PG 1
hs_code: 29333990
risk_code: 25-36/37/38-43-20/21/22
Signal word: Danger
Symbol(GHS): GHS06
hazard_code: T,Xi,Xn
hazard_note: Irritant/Toxic
safety_code: 26-36/37-45-36
hazard_class: 6.1
Storage Class: 6.1B - Non-combustible acute toxic Cat. 1 and 2very toxic hazardous materials
packing_group: III
target organs: Respiratory system
Hazard statements: H300-H315-H317-H319-H335
Limited Quantities: 5.0 kg (11 lbs) (solid)
Excepted Quantities: Max Inner Pack (30g or 30ml) and Max Outer Pack (1Kg or 1L)
Hazard Classifications: Acute Tox. 2 OralEye Irrit. 2Skin Irrit. 2Skin Sens. 1STOT SE 3
Precautionary statements: P280-P301+P310+P330-P302+P352-P305+P351+P338