CAS 112-75-4 N,N-Dimethyltetradecylamine (HCID 8211)

Overview

See also: Dimethyltetradecanamine (annotation moved to).

Names & identifiers

Preferred name: N,N-Dimethyltetradecylamine
IUPAC: N,N-dimethyltetradecan-1-amine
English name: 1-(Dimethylamino)tetradecane
Molecular formula: C16H35N
Molecular weight: 241.46

Names & synonyms

N,N-Dimethyltetradecylamine112-75-4N,N-dimethyltetradecan-1-amine1-(Dimethylamino)tetradecaneN,N-DimethylmyristylamineDIMETHYL MYRISTAMINEDimethyltetradecylamineTetradecyldimethylamineDimethyl(tetradecyl)amine1-Tetradecanamine, N,N-dimethyl-Armeen DM 14DDimethylmyristamine

Show more names

MYRISTYL DIMETHYLAMINEDMA14

N,N-Dimethyl-N-tetradecylamineN,N-Dimethyl-1-tetradecanamineDimethylmyristylamineMyristyldimethylamineN,N-DimethyltetradecanamineDimethyl-n-tetradecylamineTetradecylamine, N,N-dimethyl-Myristyl dimethyl amine

Database identifiers

CAS: 112-75-4
PubChem CID: 8211
DTXSID: DTXSID4026927
ChEMBL: CHEMBL1886777
UNII: 5E4O85D8T2
EC Number: 204-002-4
Nikkaji: J121.780A

Properties

Computed structural properties

XLogP: 6.9
Topological polar surface area: 3.2 Å²
Hydrogen bond donors: 0
Hydrogen bond acceptors: 1
Rotatable bonds: 13
Heavy atoms: 17
Formal charge: 0
Complexity: 131

Experimental & physicochemical properties

Chemical ClassesNitrogen Compounds -> Amines, Aliphatic

Cosmetics · 3 items

Cosmetic ingredients (Dimethyl Myristamine) -> CIR (Cosmetic Ingredient Review)

Personal care product -> emollient -> DIMLA: dimethyl lauryl amine

Hair conditioning; Antistatic

SpringerMaterials PropertiesBoiling point

Color/FormLIQUID

Vapor Pressure0.0015 [mmHg]

Physical Description · 2 items

CBI; Liquid

Light yellow liquid with a fishy odor; [CAMEO] Colorless to yellow liquid; Clear or slightly cloudy with a fishy odor; [MSDSonline]

Physicochemical properties

Melting point: -3 °C · -3°C
Boiling point: 148 °C · 148 °C / 2mmHg
Density: 0.795 g/mL · 0.795 g/mL at 20 °C (lit.)
vapor pressure: 0.02 · 0.02-9.4Pa at 20-50℃
refractive index: 20 · n20/D 1.441
Flash point: 131 °C · 131 °C
storage temp.: Room Temperature
solubility: Chloroform (Slightly), Hexane (Slightly), Methanol (Slightly)
pka: 9.78 · 9.78±0.28(Predicted)
form: Oil
color: Clear Colourless
BRN: 1748246 · 1748246
Cosmetics Ingredients Functions: ANTISTATICHAIR CONDITIONING
Cosmetic Ingredient Review (CIR): 1 · 1-(Dimethylamino)tetradecane (112-75-4)
InChI: 1S/C16H35N/c1-4-5-6-7-8-9-10-11-12-13-14-15-16-17(2)3/h4-16H2,1-3H3
InChIKey: SFBHPFQSSDCYSL-UHFFFAOYSA-N
SMILES: CCCCCCCCCCCCCCN(C)C
LogP: 1.3 · 1.3-6.91 at 20℃ and pH7.1-8.8
Surface tension: 25.2 · 25.2-26.5mN/m at 1g/L and 25℃
Dissociation constant: 9.78 at · 9.78 at 25℃
CAS DataBase Reference: 112 · 112-75-4(CAS DataBase Reference)
EWG's Food Scores: 1 · 1-2
FDA UNII: 5 E4O85D8T2 · 5E4O85D8T2
NIST Chemistry Reference: 1 · 1-Tetradecanamine, n,n-dimethyl-(112-75-4)
EPA Substance Registry System: -1 · N,N-Dimethyl-1-tetradecanamine (112-75-4)
UNSPSC Code: 12352100 · 12352100
NACRES: 22 · NA.22
Symbol(GHS): 7 · GHS07,GHS09
Signal word: Warning
Hazard statements: 302 · H302-H315-H400
Precautionary statements: 273 · P273-P301+P312+P330-P302+P352
PPE: Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter
Hazard Codes: C
Risk Statements: 22 · 22-34
Safety Statements: 26 · 26-36/37/39-45
RIDADR: 2735 · UN 2735 8/PG 3
WGK Germany: 3 · 3
F: 10 · 10-34
TSCA: TSCA listed
HS Code: 2921.19 · 2921.19.6190
HazardClass: 8 · 8
PackingGroup: III
Storage Class: 10 · 10 - Combustible liquids
Hazard Classifications: 4 OralAquatic · Acute Tox. 4 OralAquatic Acute 1Skin Irrit. 2
Hazardous Substances Data: 112 · 112-75-4(Hazardous Substances Data)
REACH Registrations: Active
Limited Quantities: 5 L · 5.0 L (1.3 gallons) (liquid) or 5.0 kg (11 lbs) (solid)
Excepted Quantities: Max Inner Pack (30g or 30ml) and Max Outer Pack (1Kg or 1L)

Safety & regulation

GHS classification

GHS Classification · 6 items

This chemical does not meet GHS hazard criteria for 2% (12 of 591) of reports.

Danger

H302 (97.6%): Harmful if swallowed [Warning Acute toxicity, oral]

P260, P264, P264+P265, P270, P273, P280, P301+P317, P301+P330+P331, P302+P361+P354, P304+P340, P305+P354+P338, P316, P317, P321, P330, P363, P391, P405, and P501 (click each P-code to see the statement)

Aggregated GHS information provided per 591 reports by companies from 18 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

Danger

Hazard information

Regulatory Information · 4 items

Chemical: 1-Tetradecanamine, N,N-dimethyl-

1-Tetradecanamine, N,N-dimethyl- is listed on the EPA's Chemical Data Reporting (CDR) system. Manufacturers and importers of 1-Tetradecanamine, N,N-dimethyl- are required to report information about their production and use of this chemical to the EPA under the Toxic Substances Control Act (TSCA). (40 eCFR Part 711)

Status: Active Update: 25-09-2021 https://echa.europa.eu/registration-dossier/-/registered-dossier/14714

1-Tetradecanamine, N,N-dimethyl-: Does not have an individual approval but may be used as a component in a product covered by a group standard. It is not approved for use as a chemical in its own right.

Other Safety InformationIMAP assessments - Tertiary aliphatic (C12-22) and fatty amines: Human health tier II assessment

Hazards Summary · 1 item

Emergency treatment: Detergents-cationic; [HSDB] Negative for mutagenicity in two strains of Salmonella typhimurium; [EPA HPVIS] A corrosive substance that can cause injury to the skin, eyes, and respiratory tract; Inhalation may cause pulmonary edema; [Aldrich MSDS]

Hazard Classes and Categories · 3 items

Acute Tox. 4 (97.6%)

Acute toxicity - category 4

Acute toxicity (Oral) - Category 4

Toxicology

Adverse EffectsDermatotoxin - Skin burns.

Toxicity SummarySafe in the present practices of use and concentration. Ingredient, concentration, and use information are available in documents discoverable at https://cir-reports.cir-safety.org

Safety data

F: 10-34
PPE: Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter
wgk: 3
tsca: TSCA listed
ridadr: UN 2735 8/PG 3
hs_code: 2921.19.6190
risk_code: 22-34
Signal word: Warning
Symbol(GHS): GHS07,GHS09
hazard_code: C
safety_code: 26-36/37/39-45
hazard_class: 8
Storage Class: 10 - Combustible liquids
packing_group: III
Hazard statements: H302-H315-H400
Limited Quantities: 5.0 L (1.3 gallons) (liquid) or 5.0 kg (11 lbs) (solid)
Excepted Quantities: Max Inner Pack (30g or 30ml) and Max Outer Pack (1Kg or 1L)
REACH Registrations: Active
Hazard Classifications: Acute Tox. 4 OralAquatic Acute 1Skin Irrit. 2
Precautionary statements: P273-P301+P312+P330-P302+P352
Hazardous Substances Data: 112-75-4(Hazardous Substances Data)

Chemistry & industry

Uses & manufacturing

Uses · 3 items

CIR ingredient: Dimethyl Myristamine

Used as cationic detergent and corrosion inhibitor; [HSDB] Used to make other chemicals; [CAMEO]

CATIONIC DETERGENT; CORROSION INHIBITOR

U.S. Production2023: 40,000,000 - <55,000,000 lb

Consumer UsesSurfactant (surface active agent)

Industry UsesSurfactant (surface active agent)

Use ClassificationCosmetics -> Hair conditioning; Antistatic

General Manufacturing Information · 2 items

Oil and Gas Drilling, Extraction, and Support activities

1-Tetradecanamine, N,N-dimethyl-: ACTIVE

Applications · 4 items

UsesBarlene(R) tertiary amines are used as chemical intermediates for the manufacture of quaternary ammonium compounds, amine oxide and betaine surfactants

UsesN,N-Dimethyltetradecylamine (cas# 112-75-4) is a compound useful in organic synthesis.

UsesN,N-Dimethyltetradecylamine has been used for the synthesis of 1,6-bis(N,N-tetradecyl dimethylammonium adipate), a counterion coupled gemini (cocogem) surfactant. It may also be used in the following studies:For the isolation of recombinant botulinum neurotoxin fragments in the yeast Pichia pastoris by cell permeabilization method.Synthesis of gemini surfactants belonging to the series of alkanediyl-α,ω-bis-(dimethylalkyl ammonium bromide, which were evaluated as corrosion inhibitors of iron in hydrochloric acid medium.Preparation of cationic gemini surfactant of the type N-alkanediyl 1,2-ethane bis(dimethyl ammonium bromide).

General DescriptionA light yellow liquid with a fishlike odor. Insoluble in water and less dense than water. Hence floats on water. Contact may irritate skin, eyes and mucous membranes. May be toxic by ingestion, inhalation or skin absorption. Used to make other chemicals.