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Arsenic pentafluoride

HCID 82223
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Basic informationOverviewNames & identifiersPropertiesSafety & regulationChemistry & industryRelated reactionsCompound notes
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Basic information

CAS
7784-36-3
Standard SMILES
F[As](F)(F)(F)F
InChIKey
YBGKQGSCGDNZIB-UHFFFAOYSA-N
Molecular formula
AsF5
Average molar mass
169.9136 g/mol
Monoisotopic mass
169.91361

Overview

Arsenic pentafluoride is a pnictogen halide.

Names & identifiers

Preferred name
Arsenic pentafluoride
IUPAC
pentafluoro-λ5-arsane
English name
ARSENIC PENTAFLUORIDE
Molecular formula
AsF5
Molecular weight
169.91

Names & synonyms

Arsenic pentafluoridePentafluoroarsorane7784-36-3Arsorane, pentafluoro-AsF5pentafluoro-lambda5-arsanepentafluoridoarsenicI54752Q0OJpentafluoro-lambda(5)-arsaneDTXSID4064842CHEBI:30530(AsF5)
Show more names
Arsenicfluoride2Einecs 232-061-6PentafluoroarsineARSENIC (V) FLUORIDEArsenic pentfluorideFive fluoride arsenicArsenic(V)pentafluoride
[AsF5]RefChem:114185DTXCID1048045232-061-6arsenic(V) fluorideArsenic fluoride (AsF5)UNII-I54752Q0OJarsenic(V)fluoride

Database identifiers

CAS
7784-36-3
PubChem CID
82223
DTXSID
DTXSID4064842
ChEBI
CHEBI:30530
UNII
I54752Q0OJ
EC Number
232-061-6
Nikkaji
J95.336I

Properties

Computed structural propertiesFilling in

Topological polar surface area
0 Ų
Hydrogen bond donors
0
Hydrogen bond acceptors
5
Rotatable bonds
0
Heavy atoms
6
Formal charge
0
Complexity
37.1

Experimental & physicochemical properties

Chemical Classes · 2 items

Metals -> Arsenic Compounds, Inorganic

Carcinogens

Physical DescriptionColorless gas; Makes white clouds in moist air; Hydrolyzed instantly by water; [Merck Index]

Physicochemical properties

Melting point
-79 · -79,8°C
Boiling point
-52 · -52,8°C
Density
25.8 · dliq25.8 2.33
solubility
2 O; · reacts with H2O; soluble in ethanol,benzene, ethyl ether
form
colorless gas
color
colorless
Water Solubility
2 O;soluble · hydrolyzed quickly in H2O;soluble alcohol, benzene, ether [MER06]
CAS DataBase Reference
7784 · 7784-36-3
REACH Annex XVII Substances List
Pentafluoroarsorane (7784-36-3)
FDA UNII
54752 Q0OJ · I54752Q0OJ

Safety & regulation

Safety information is for reference only and does not replace the supplier’s Safety Data Sheet (SDS), applicable regulations, or professional assessment.

GHS classification

GHS Classification · 6 items

Danger

H280 (100%): Contains gas under pressure; may explode if heated [Warning Gases under pressure]

P260, P271, P273, P284, P304+P340, P316, P320, P391, P403+P233, P405, P410+P403, and P501 (click each P-code to see the statement)

Aggregated GHS information provided per 111 reports by companies from 1 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

Danger

H280: Contains gas under pressure; may explode if heated [Warning Gases under pressure]

Hazard information

Regulatory Information · 2 items

Restricted substance: Pentafluoroarsorane

The New Jersey Worker and Community Right to Know Act requires public and private employers to provide information about hazardous substances at their workplaces. (N.J.S.A. 34:5A-1 et. seq.)

Hazards SummarySee Arsenic and the linked occupational diseases.
Hazard Classes and Categories · 4 items

Press. Gas (Liq.) (100%)

Gases under pressure - Compressed gas or Liquefied gas

Gases under pressure - Compressed gas or Liquefied gas

Carcinogens, Reactive agents - 1st degree

Safety & protection

Exposure Control and Personal Protection · 2 items

Biological Exposure Indices (BEI) [ACGIH] - Inorganic arsenic plus methylated metabolites in urine = 35 ug As/L; end of workweek; Fluorides in urine = 2 mg/L prior to shift or 3 mg/L at end of shift; (Repeated measurements recommended.)

Chemistry & industry

Pharmacology

Metabolism/Metabolites · 1 item

Arsenic is absorbed mainly by inhalation or ingestion, as to a lesser extent, dermal exposure. It is then distributed throughout the body, where it is reduced into arsenite if necessary, then methylated into monomethylarsenic (MMA) and dimethylarsenic acid (DMA) by arsenite methyltransferase. Arsenic and its metabolites are primarily excreted in the urine. Arsenic is known to induce the metal-binding protein metallothionein, which decreases the toxic effects of arsenic and other metals by binding them and making them biologically inactive, as well as acting as an antioxidant. (L20)

Uses & manufacturing

Uses · 2 items

Used in electroconductive polymers as a doping agent; [Hawley]

Semiconductor Manufacturing [Category: Industry]

General Manufacturing InformationArsorane, pentafluoro-: ACTIVE

Applications

UsesDoping agent in electroconductive polymers.

Additional notes

DefinitionReadily hydrolyzed, soluble in alcohol and benzene.

Related reactions

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Compound notes

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EPA Substance Registry System
Arsenic pentafluoride (7784-36-3)
Symbol(GHS)
9 · GHS09,GHS04,GHS06
Signal word
Danger
Hazard statements
280 · H280-H330-H410-H400
Precautionary statements
273 · P273-P391-P501-P273-P391-P501-P260-P271-P284-P304+P340-P310-P320-P403+P233-P405-P501-P410+P403
Hazard Codes
T
Risk Statements
23 · 23/25
Safety Statements
20 · 20/21-28-45
RIDADR
3162 · 3162
Hazard Note
Toxic
TSCA
TSCA listed
HazardClass
2.3 · 2.3

1.0 [mg/m3], inhalable fraction, as F[German Research Foundation (DFG)]

Minimum Risk LevelAcute Oral: 0.005 mg/kg/day (L134) Chronic Oral: 0.0003 mg/kg/day (L134) Chronic Inhalation: 0.01 mg/m3 (L134)
Threshold Limit Values (TLV)0.01 [mg/m3], as As (2.5 mg/m3, as F)
Permissible Exposure Limit (PEL)0.01 [mg/m3], as As (2.5 mg/m3, as F)
Immediately Dangerous to Life or Health (IDLH)5.0 [mg/m3], as As

Toxicology

Treatment · 1 item

Arsenic poisoning can be treated by chelation therapy, using chelating agents such as dimercaprol, EDTA or DMSA. Charcoal tablets may also be used for less severe cases. In addition, maintaining a diet high in sulfur helps eliminate arsenic from the body. (L20)

Health EffectsArsenic poisoning can lead to death from multi-system organ failure, probably from necrotic cell death, not apoptosis. Arsenic is also a known carcinogen, esepcially in skin, liver, bladder and lung cancers. (T1, L20)
Adverse EffectsNeurotoxin - Sensorimotor
Exposure RoutesOral (L2) ; inhalation (L2) ; dermal (L2)
Toxicity Summary · 1 item

Arsenic and its metabolites disrupt ATP production through several mechanisms. At the level of the citric acid cycle, arsenic inhibits pyruvate dehydrogenase and by competing with phosphate it uncouples oxidative phosphorylation, thus inhibiting energy-linked reduction of NAD+, mitochondrial respiration, and ATP synthesis. Hydrogen peroxide production is also increased, which might form reactive oxygen species and oxidative stress. Arsenic's carginogenicity is influenced by the arsenical binding of tubulin, which results in aneuploidy, polyploidy and mitotic arrests. The binding of other arsenic protein targets may also cause altered DNA repair enzyme activity, altered DNA methylation patterns and cell proliferation. (T1, A17)

Signs and SymptomsExposure to lower levels of arsenic can cause nausea and vomiting, decreased production of red and white blood cells, abnormal heart rhythm, damage to blood vessels, and a sensation of
Carcinogen Classification1, carcinogenic to humans. (L135)

Safety data

tsca
TSCA listed
ridadr
3162
risk_code
23/25
Signal word
Danger
Symbol(GHS)
GHS09,GHS04,GHS06
hazard_code
T
hazard_note
Toxic
safety_code
20/21-28-45
hazard_class
2.3
Hazard statements
H280-H330-H410-H400
Precautionary statements
P273-P391-P501-P273-P391-P501-P260-P271-P284-P304+P340-P310-P320-P403+P233-P405-P501-P410+P403