Basic information
- CAS
116-45-0- Standard SMILES
Cc1nc(NS(=O)(=O)c2ccc(N)cc2)nc(C)c1Br- InChIKey
KWXCNODTHBHSIQ-UHFFFAOYSA-N- Molecular formula
- C12H13BrN4O2S
- Average molar mass
- 357.23 g/mol
- Monoisotopic mass
- 355.99426
Overview
Sulfabromomethazine is a sulfonamide consisting of 5-bromo-4,6-dimethylpyrimidine with a 4-aminobenzenesulfonamido group at the 2-position. A long-acting derivative of sulfamezathine, it is used in the poultry, swine and cattle industries for the treatment of coccidiosis and various bacterial infections. It has a role as an antibacterial agent. It is functionally related to a sulfamethazine.
Names & identifiers
- Preferred name
- Sulfabromomethazine
- IUPAC
- 4-amino-N-(5-bromo-4,6-dimethylpyrimidin-2-yl)benzenesulfonamide
- English name
- 4-amino-N-(5-bromo-4,6-dimethyl-2-pyrimidinyl)benzenesulphonamide
- Molecular formula
- C12H13BrN4O2S
- Molecular weight
- 357.22622
Names & synonyms
SulfabromSULFABROMOMETHAZINE116-45-05-BromosulfamethazineBromosulfamethazine4-amino-N-(5-bromo-4,6-dimethylpyrimidin-2-yl)benzenesulfonamideDTXSID5046857UNII-PQK2N461KJNSC 5874NSC-5874PQK2N461KJNSC5874
Show more names
N 3517Sulfabrom, 10 mM in DMSOBacterial,Sulfabrom,inhibit,Inhibitor,N-3517,N3517N'-(5-bromo-4,6-dimethylpyrimidin-2-yl)sulfanylamide4-amino-N-(5-bromo-4,6-dimethyl-pyrimidin-2-yl)benzenesulfonamide4-amino-N-(5-bromo-4,6-dimethyl-2-pyrimidinyl)benzenesulphonamide
CHEBI:145405S. N. 3517EINECS 204-142-6SULFABROMOMETHAZINE [MI]DTXCID30268574-Amino-N-(5-bromo-4,6-dimethyl-2-pyrimidinyl)benzenesulfonamide4-amino-N-(5-bromo-4,6-dimethylpyrimidin-2-yl)benzene-1-sulfonamideBenzenesulfonamide, 4-amino-N-(5-bromo-4,6-dimethyl-2-pyrimidinyl)-
Database identifiers
- CAS
116-45-0
Properties
Computed structural properties
- XLogP
- 1
- Topological polar surface area
- 106 Ų
- Hydrogen bond donors
- 2
- Hydrogen bond acceptors
- 6
- Rotatable bonds
- 3
- Heavy atoms
- 20
- Formal charge
- 0
- Complexity
- 408
Experimental & physicochemical properties
DrugsPharmaceuticals -> Antibiotics
Physicochemical properties
- Melting point
- 246 ℃ · approximate 246℃ (dec.)
- Boiling point
- 568.3 · 568.3±60.0 °C(Predicted)
- Density
- 1.653 · 1.653±0.06 g/cm3(Predicted)
- storage temp.
- -20 °C · Store at -20°C
- solubility
- Acetonitrile (Slightly, Heated), DMSO (Slightly)
- form
- Solid
- pka
- 7.16 · 7.16±0.10(Predicted)
- color
- Yellow to Dark Yellow
- FDA UNII
- 2 N461KJ · PQK2N461KJ
Chemistry & industry
Applications
UsesSulfabromomethazine is a veterinary antibacterial drug.
UsesDrug (veterinary); food additive.
Suppliers23 total
上海毕得医药科技股份有限公司400-1647117 13681763483 · [email protected]
上海冬洋生物科技有限公司0512-13601744364 13601744364 · [email protected]
宁波季诺化学品有限公司0574-87314919 057487319282 · [email protected]
Nantong HI-FUTURE Biology Co., Ltd.+86-18051384581 · [email protected]
MedChemexpress LLC021-58955995 · [email protected]
陕西缔都医药化工有限公司029-81024372 17792795018 · [email protected]
上海碧咸医药科技有限公司13816613772 · [email protected]
上海陶术生物科技股份有限公司+1-781-999-5354; +1-00000000000 · [email protected]
艾吉析科技（上海）有限公司17717235263 17717235263 · [email protected]
南通全益生物科技有限公司0513-66337626 18051384581 · [email protected]
上海一飞生物科技有限公司021-65675885 18964387627 · [email protected]
上海立崎生物医学研究中心18014399201 · [email protected]
Related reactions
0 records
No reaction records under the current filter.
Compound notes
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