Erythromycin dihydrate
Basic information
- CAS
59319-72-1- Standard SMILES
CC[C@H]1OC(=O)[C@H](C)[C@@H](O[C@H]2C[C@@](C)(OC)[C@@H](O)[C@H](C)O2)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)C[C@H](N(C)C)[C@H]2O)[C@](C)(O)C[C@@H](C)C(=O)[C@H](C)[C@@H](O)[C@]1(C)O.O.O- InChIKey
IWGQNYZQLVGGCS-INORWZNNSA-N- Molecular formula
- C37H71NO15
- Average molar mass
- 770 g/mol
- Monoisotopic mass
- 769.48237056
Names & identifiers
- Preferred name
- Erythromycin dihydrate
- IUPAC
- (3R,4S,5S,6R,7R,9R,11R,12R,13S,14R)-6-[(2S,3R,4S,6R)-4-(dimethylamino)-3-hydroxy-6-methyloxan-2-yl]oxy-14-ethyl-7,12,13-trihydroxy-4-[(2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyloxan-2-yl]oxy-3,5,7,9,11,13-hexamethyl-oxacyclotetradecane-2,10-dione;dihydrate
- English name
- ERYTHROMYCIN A DIHYDRATE
- Molecular formula
- C37H67NO13.H2O
- Molecular weight
- 751.945
Names & synonyms
Erythromycin dihydrateErythromycin, dihydrateUNII-T0O317A6OWT0O317A6OW59319-72-1DTXSID601016197RefChem:137786DTXCID701474334Erythromycin A (dihydrate)Erythromycin A dihydrate(3R,4S,5S,6R,7R,9R,11R,12R,13S,14R)-6-[(2S,3R,4S,6R)-4-(dimethylamino)-3-hydroxy-6-methyloxan-2-yl]oxy-14-ethyl-7,12,13-trihydroxy-4-[(2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyloxan-2-yl]oxy-3,5,7,9,11,13-hexamethyl-oxacyclotetradecane-2,10-dione;dihydrateSCHEMBL10381573
Show more names
Erythromycin A, EvoPureRoxithromycin Impurity AERYTHROMYCIN A, DIHYDRATE VETRANALErythromycin A dihydrateQ: What is Erythromycin A dihydrate Q: What is the CAS Number of Erythromycin A dihydrate Q: What is the storage condition of Erythromycin A dihydrate
HY-B0220EDA-52996CS-0129423Q27289514(3R,4S,5S,6R,7R,9R,11R,12R,13S,14R)-6-{[(2S,3R,4S,6R)-4-(Dimethylamino)-3-hydroxy-6-methyloxan-2-yl]oxy}-14-ethyl-7,12,13-trihydroxy-4-{[(2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyloxan-2-yl]oxy}-3,5,7,9,11,13-hexamethyl-1-oxacyclotetradecane-2,10-dione--water (1/2)
Properties
Computed structural properties
- Topological polar surface area
- 196 Ų
- Hydrogen bond donors
- 7
- Hydrogen bond acceptors
- 16
- Rotatable bonds
- 7
- Heavy atoms
- 53
- Formal charge
- 0
- Complexity
- 1,180
Physicochemical properties
- Melting point
- 197.6 °C · 197.6 °C
- FDA UNII
- 0 O317A6OW · T0O317A6OW
- WGK Germany
- 2 · 2
- RTECS
- 4375000 · KF4375000
Safety & regulation
Safety information is for reference only and does not replace the supplier’s Safety Data Sheet (SDS), applicable regulations, or professional assessment.
Safety data
- wgk
- 2
- rtecs
- KF4375000
Chemistry & industry
Applications
UsesErythromycin A dihydrate is a macrolide antibiotic produced by actinomyceteStreptomyces erythreuswith a broad spectrum of antimicrobial activity. Erythromycin A dihydrate binds to bacterial 50S ribosomal subunits and inhibitsRNA-dependent protein synthesisby blockage of transpeptidation and/or translocation reactions, without affecting synthesis of nucleic acid[1][2]. Erythromycin A dihydrate also exhibits antitumor and neuroprotective effect in different fields of research[3][4].
Suppliers
Loading…
Open inquiries
Loading…
Related reactions
0 records
No reaction records under the current filter.
Compound notes
Loading…