o-Chlorophenyl dichlorophosphate
Basic information
- CAS
15074-54-1- Standard SMILES
O=P(Cl)(Cl)Oc1ccccc1Cl- InChIKey
VLDPXPPHXDGHEW-UHFFFAOYSA-N- Molecular formula
- C6H4Cl3O2P
- Average molar mass
- 245.4 g/mol
- Monoisotopic mass
- 243.901449
Names & identifiers
- Preferred name
- o-Chlorophenyl dichlorophosphate
- IUPAC
- 1-chloro-2-dichlorophosphoryloxybenzene
- English name
- 2-Chlorophenyl phosphorodichloridate
- Molecular formula
- C6H4Cl3O2P
- Molecular weight
- 245.43
Names & synonyms
15074-54-1Phosphorodichloridic acid, 2-chlorophenyl estero-Chlorophenyl dichlorophosphateDTXSID90164600EINECS 239-129-4RefChem:855220DTXCID3087091239-129-42-Chlorophenyl phosphorodichloridate2-Chlorophenyl dichlorophosphate1-chloro-2-dichlorophosphoryloxybenzeneMFCD00009704
Show more names
2-CHLOROPHENYL DICHLOROPHOSPATEChlorophenylphosphoryl Dichloride2-Chlorophenyl dichloridophosphateo-Chlorophenylphosphonyl dichloride2-CHLOROPHENYL PHOSPHO DICHLORIDATE2-Chlorophenyl dichlorophosphate,99%
YH4YQB3GEF2-Chlorophenylphosphoryl Dichloride(2-Chlorophenyl)phosphoric acid dichlorideAKOS015888982C0976o-chlorophenyl phosphorodichloridateUNII-YH4YQB3GEFA884139
Database identifiers
- CAS
15074-54-1- PubChem CID
- 84775
- DTXSID
DTXSID90164600- UNII
- YH4YQB3GEF
- EC Number
- 239-129-4
- Nikkaji
- J150.102J
Properties
Computed structural properties
- XLogP
- 3.6
- Topological polar surface area
- 26.3 Ų
- Hydrogen bond donors
- 0
- Hydrogen bond acceptors
- 2
- Rotatable bonds
- 2
- Heavy atoms
- 12
- Formal charge
- 0
- Complexity
- 193
Experimental & physicochemical properties
SpringerMaterials PropertiesNuclear quadrupole resonance spectroscopy
Physicochemical properties
- Boiling point
- 135 · 135-137 °C12 mm Hg(lit.)
- Density
- 1.491 g/mL · 1.491 g/mL at 25 °C(lit.)
- refractive index
- 20 · n20/D 1.538(lit.)
- Flash point
- 221 °F · 221 °F
- storage temp.
- Inert atmosphere,Room Temperature
- form
- clear liquid
- color
- Colorless to Light yellow to Light orange
- Sensitive
- Moisture Sensitive
- BRN
- 911009 · 911009
- InChI
- InChI=1S/C6H4Cl3O2P/c7-5-3-1-2-4-6(5)11-12(8,9)10/h1-4H
- InChIKey
- VLDPXPPHXDGHEW-UHFFFAOYSA-N
- SMILES
- P(Cl)(Cl)(OC1=CC=CC=C1Cl)=O
Safety & regulation
Safety information is for reference only and does not replace the supplier’s Safety Data Sheet (SDS), applicable regulations, or professional assessment.
GHS classification
GHS Classification
Danger
H314 (100%): Causes severe skin burns and eye damage [Danger Skin corrosion/irritation]
P260, P264, P280, P301+P330+P331, P302+P361+P354, P304+P340, P305+P354+P338, P316, P321, P363, P405, and P501 (click each P-code to see the statement)
Aggregated GHS information provided per 44 reports by companies from 3 notifications to the ECHA C&L Inventory.
Hazard information
Hazard Classes and CategoriesSkin Corr. 1C (100%)
Safety data
- F
- 9
- PPE
- Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter
- wgk
- 3
- ridadr
- UN 3265 8/PG 2
- hs_code
- 29199000
- risk_code
- 34
- Signal word
- Danger
- Symbol(GHS)
- GHS05
- hazard_code
- C
- safety_code
- 26-36/37/39-45
- hazard_class
- 8
- Storage Class
- 8A - Combustible corrosive hazardous materials
- packing_group
- II
- Hazard statements
- H314
- Hazard Classifications
- Skin Corr. 1B
- Precautionary statements
Chemistry & industry
Applications
UsesPhosphorylating reagent for oligonucleotide synthesis via the triester method.1
Uses2-Chlorophenyl phosphorodichloridate has been used in the preparation of:mononucleotide building blocksoligonucleotides and oligonucleotide phosphorothioates in solution
Upstream & downstream products
Upstream raw materials
Downstream products
Suppliers
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Related reactions
1 records
Compound notes
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