Ethanedioyl dibromide (HCID 84841)

Names & identifiers

Preferred name: Ethanedioyl dibromide
IUPAC: oxalyl dibromide
English name: OXALYL BROMIDE
Molecular formula: C2Br2O2
Molecular weight: 215.83

Names & synonyms

Oxalyl bromideEthanedioyl dibromide15219-34-8oxalyl dibromideEthanedioyl bromideoxalylbromideMFCD00000113YZQ2D2RT2QNSC-96957NSC 96957C2Br2O2BrCOCOBr

Show more names

OBLEPDCAD11CDHOBOXALYL BROMOOxaly bromideOxayl Bromide

EINECS 239-271-7Oxalyl bromide, 97%UNII-YZQ2D2RT2QSCHEMBL186868DTXSID9065869NSC96957AKOS015901745AS-85803

Database identifiers

CAS: 15219-34-8
PubChem CID: 84841
DTXSID: DTXSID9065869
UNII: YZQ2D2RT2Q
EC Number: 239-271-7
Nikkaji: J218.380C

Properties

Computed structural properties

XLogP: 1.8
Topological polar surface area: 34.1 Å²
Hydrogen bond donors: 0
Hydrogen bond acceptors: 2
Rotatable bonds: 1
Heavy atoms: 6
Formal charge: 0
Complexity: 75.5

Experimental & physicochemical properties

Chemical ClassesOther Classes -> Halogenated Ketones

SpringerMaterials PropertiesSchoenflies notation

Physical DescriptionClear dark yellow liquid; [Sigma-Aldrich MSDS]

Physicochemical properties

Melting point: -19 °C · -19 °C (lit.)
Boiling point: 16 · 16-17 °C/10 mmHg (lit.)
Density: 1.517 g/mL · 1.517 g/mL at 25 °C
refractive index: 20 · n20/D 1.522(lit.)
Flash point: -19 °C · -19°C
storage temp.: 2 · 2-8°C
solubility: Benzene (Slightly), Chloroform
form: Liquid
color: Clear
biological source: goat
BRN: 1744437 · 1744437
Stability: Moisture Sensitive
InChI: InChI=1S/C2Br2O2/c3-1(5)2(4)6
InChIKey: JAZLVNXWYDFQFE-UHFFFAOYSA-N
SMILES: C(Br)(=O)C(Br)=O
CAS DataBase Reference: 15219 · 15219-34-8
FDA UNII: 2 D2RT2Q · YZQ2D2RT2Q
EPA Substance Registry System: Ethanedioyl dibromide (15219-34-8)
UNSPSC Code: 51111800 · 51111800
NACRES: 41 · NA.41
Symbol(GHS): 5 · GHS05,GHS07
Signal word: Danger
Hazard statements: 314 · H314-H332
Precautionary statements: 261 · P261-P271-P280-P303+P361+P353-P304+P340+P310-P305+P351+P338
PPE: Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter
Hazard Codes: C,T
Risk Statements: 23 · 23/24/25-34-40-29-20-14-37
Safety Statements: 26 · 26-36/37/39-45-28-27
RIDADR: 3265 · UN 3265 8/PG 2
WGK Germany: 3 · 3
F: 8 · 8-9
TSCA: TSCA listed
HazardClass: 8 · 8
PackingGroup: II
HS Code: 29171990 · 29171990
Storage Class: 6.1 A · 6.1A - Combustible acute toxic Cat. 1 and 2very toxic hazardous materials
Hazard Classifications: 4 InhalationEye · Acute Tox. 4 InhalationEye Dam. 1Skin Corr. 1B

Safety & regulation

GHS classification

GHS Classification · 4 items

Danger

H314 (100%): Causes severe skin burns and eye damage [Danger Skin corrosion/irritation]

P260, P261, P264, P264+P265, P271, P280, P301+P330+P331, P302+P361+P354, P304+P340, P305+P354+P338, P316, P317, P321, P363, P405, and P501 (click each P-code to see the statement)

Aggregated GHS information provided per 40 reports by companies from 2 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

Hazard information

Hazards SummaryReacts violently with water; Causes burns; Inhalation may cause corrosive injuries to upper respiratory tract and lungs; Harmful by inhalation; [Sigma-Aldrich MSDS]

Hazard Classes and CategoriesSkin Corr. 1B (100%)

Toxicology

Adverse EffectsDermatotoxin - Skin burns.

Safety data

F: 8-9
PPE: Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter
wgk: 3
tsca: TSCA listed
ridadr: UN 3265 8/PG 2
hs_code: 29171990
risk_code: 23/24/25-34-40-29-20-14-37
Signal word: Danger
Symbol(GHS): GHS05,GHS07
hazard_code: C,T
safety_code: 26-36/37/39-45-28-27
hazard_class: 8
Storage Class: 6.1A - Combustible acute toxic Cat. 1 and 2very toxic hazardous materials
packing_group: II
Hazard statements: H314-H332
Hazard Classifications: Acute Tox. 4 InhalationEye Dam. 1Skin Corr. 1B
Precautionary statements: P261-P271-P280-P303+P361+P353-P304+P340+P310-P305+P351+P338

Chemistry & industry

Uses & manufacturing

General Manufacturing InformationEthanedioyl dibromide: ACTIVE

Applications · 2 items

UsesUsed in synthetic applications of carbon-substituted iminium saltsReactant for:Synthesis of mutasynthons added to cultures of A. pretiosum for mutasynthetic generation of ansamitocin derivativesOxalic acid formation from hydroxyl radical substitutionsCyclization to produce CRF1 receptor antagonistsPreparation, optical and electrochemical studies of thiophene end capped olig(2,3-alkylthieno[3,4-b]pyrazine)Asymmetrical synthesis of glycosyl chlorides and bromides

UsesLeptin from rat has been used:to check the effect of intranasal nerve growth factor (NGF) on NGF activity in the spinal cord of Sprague-Dawley ratsfor validation of labelling for leptin-bearing cells of Sprague-Dawley ratsto study the effect of leptin on STAT3 (signal transducer and activator of transcription 3) phosphorylation in neural population of Sprague-Dawley ratsto study leptin response towards chemoreflex in nucleus of the solitary tractin rats, to check the effect of association between leptin and neuronal nitric oxide pathway on penicillin-induced epileptiform activity